DOMINIC15.21 AMIRTHARAJ15.21 -15.21 BOARD15.21 OF15.21 HEALTH15.21 CHAIR15.21 -15.21 I'd15.21 like15.38 to15.54 call15.7 the15.94 Watertown16.1 Board16.66 of16.82 Health16.98 meeting17.21 to17.54 order.17.7 Our19.21 first,19.45 agenda20.49 item,20.98 is21.7 review21.94 of22.34 draft22.49 minutes.22.82 It25.14 looks25.3 like25.61 the26.94 meeting27.42 from27.74 August28.14 20.32.46 Kim32.94 and33.02 Jessica35.02 were35.66 there.35.82 I36.14 wasn't,36.38 so36.86 I36.98 don't37.1 think37.34 we38.06 can38.22 really38.38 vote38.54 on38.7 it.38.86 39.1 ABBEY39.1 MYERS39.1 -39.1 CITY39.1 OF39.1 WATERTOWN39.1 -39.1 So39.1 we39.18 can39.66 table39.9 those40.3 once40.62 again.40.94 42.59 AMIRTHARAJ42.59 -42.59 Sure.42.59 And43.15 then43.39 the43.7 minutes44.02 from44.43 September44.75 17,45.27 I47.55 would47.7 vote48.02 to48.34 a48.91 motion49.07 to49.39 approve,49.63 with50.59 the50.91 addendum51.23 that,51.79 we52.19 have52.43 not52.59 approved52.83 the53.39 minutes53.7 from54.02 August54.34 2054.79 yet.55.23 57.48 JESSICA57.48 MALENFANT57.48 -57.48 BOARD61.24 OF61.24 HEALTH61.24 MEMBER61.24 -61.24 Second.61.24 61.24 Sorry.62.52 Maureen63.96 is64.6 in64.84 Japan,65 so65.56 it65.88 is66.04 me66.36 doing68.84 minutes.69.24 Jessica71.61 second.72.89 Perfect.73.53 And75.69 doctor76.33 Amithraj?76.73

78.81 Aye.78.81

80.42 Jessica80.42 Malafon?80.9 Aye.82.17

83.47 Perfect.83.47 Then84.27 we're84.59 all84.75 set,84.99 and85.23 those85.39 are85.71 in85.95 regards86.11 to86.75 September87.79 17.88.89 Seventeenth.90.35 Perfect.91.07 93.55 AMIRTHARAJ93.55 -93.55 Okay.93.55 Our93.95 next94.19 agenda94.51 point95.07 is95.63 opening95.87 the96.27 floor96.43 to96.75 public96.83 comment.97.23 If97.63 anyone97.79 from98.42 the98.66 public98.81 is99.06 present99.3 and99.53 would99.69 like99.86 to99.94 participate,100.09 in102.09 something102.33 directly102.73 related103.14 to103.53 health.103.94

111.23 Hi.111.23 I111.55 am111.79 Alberta,113.31 Zoummar.115.15 I115.15 think115.31 I116.91 am117.15 here117.31 fifth117.79 on118.11 the118.27 agenda.118.51 I'm119.55 not119.79 sure120.03 if120.43 I121.23 should121.47 go121.63 ahead121.87 and122.27 make122.43 a122.67 comment122.83 or123.31 I123.47 should123.63 wait.123.87

125.88 Oh,125.88 hey.125.97 Good126.13 evening.126.36 Yeah.127.81 That128.04 will128.21 be128.44 for,128.69 further130.13 down130.44 in130.69 the130.84 meeting.130.93

132.28 Okay.132.28

133.16 Thank133.16 you.133.41 Alright.136.44 If136.76 there136.93 are137.08 no137.25 other,137.41 members138.21 of138.6 the138.76 public,138.84 we'd140.69 move140.93 on.141.09 141.89 AMIRTHARAJ141.89 -141.89 The141.89 next141.97 agenda142.29 point142.61 is143.17 review143.49 of143.73 the143.81 permit144.05 application,144.37 for145.65 let147.09 me147.41 see147.49 if147.57 I147.65 pronounce147.73 this148.13 correctly,148.21 Psivant148.69 Therapeutics.149.17 149.97 CAMIL149.97 SAYEGH149.97 -149.97 PSIVANT149.97 THERAPEUTICS149.97 -149.97 Excellent.149.97 152.45 AMIRTHARAJ152.45 -152.45 Hi.152.45 Good152.69 evening.152.93 153.57 SAYEGH153.57 -153.57 Hi.153.57 156.06 AMIRTHARAJ156.06 -156.06 So156.06 my157.26 understanding157.5 is158.22 that,158.38 we160.63 were160.94 the162.94 biosafety163.1 committee163.75 was164.15 missing164.38 the164.71 emergency164.86 response165.43 info166.38 which166.78 they167.03 received,167.26 and168.54 then168.86 we170.31 want170.55 to170.71 review170.87 initiating172.79 lab173.43 work.173.59 Is173.91 that173.99 correct?174.15 175.19 SAYEGH175.19 -175.19 Correct.175.19 177.19 AMIRTHARAJ177.19 -177.19 Alright.177.19 Would177.75 you177.91 be177.99 able178.15 to178.39 give178.47 us178.63 a178.87 brief179.19 review179.43 of179.83 what180.39 you're180.55 doing?180.79 181.83 SAYEGH181.83 -181.83 Sure.181.83 I'm182.71 going182.87 to183.19 share183.19 my183.43 desktop.183.59 We184.47 have184.63 prepared184.95 some185.35 slides.185.59 Happy187.06 to187.38 walk187.53 you187.69 through.187.85

188.66 Sure.188.66

196.81 Can196.81 you197.06 see?197.29 Can198.89 you199.05 see199.13 the199.37 slides?199.53 Awesome.200.25

200.97 Yes.200.97

202.01 SAYEGH202.01 -202.01 So,202.01 yeah,202.41 just202.65 building202.89 on,203.29 a205.13 few,205.45 slides206.25 that206.65 speak206.73 to206.97 who207.29 we207.53 are207.69 and208.41 the208.81 type209.53 of209.77 work209.85 that210.09 we210.33 do210.49 and211.7 the211.91 biosafety212.1 protocols213.54 that214.1 we214.26 follow.214.98 So216.03 just216.26 very216.42 briefly,216.75 we217.94 are218.26 a218.5 company218.66 that219.22 leverages220.19 computational220.82 methods221.47 to222.5 accelerate222.66 the223.22 discovery223.31 of223.78 novel223.94 medications224.42 for225.14 patients225.38 that225.78 suffer225.94 from226.34 inflammatory227.28 and227.6 autoimmune227.92 disease.228.32 Our229.52 scientific229.76 founder230.24 has230.64 a230.8 long230.88 history231.2 in232.32 this232.48 field,232.72 dating233.44 back233.76 to234.08 2017.234.24 We236.64 are236.8 now237.04 a237.36 privately237.44 owned238 venture238.32 backed238.64 company238.96 that240.94 is241.25 engaged241.57 in241.9 that242.29 type242.46 of242.62 research242.78 activities.243.25 So,245.25 this245.9 is246.14 just246.22 a246.46 view246.53 of246.86 the247.01 overall247.25 leadership247.57 team248.06 just248.29 to248.46 highlight248.62 that249.97 this250.22 is250.38 a250.53 team250.62 that250.86 brings251.66 tremendous251.9 experience253.01 and253.5 expertise253.74 in254.38 the254.53 area254.69 of255.01 drug255.09 discovery.255.52 256.8 I'm257.2 the257.44 chief257.68 scientific258 officer258.64 of259.04 the259.2 company.259.36 I260.48 have260.64 20260.88 plus261.2 years261.52 of261.76 experience,261.92 in262.64 the262.8 industry,262.96 and263.92 rose263.92 through264.24 the264.4 labs.264.56 I've266 been266.16 indulged266.4 by266.8 training,267.04 so267.44 very267.6 familiar268 with268.64 the268.8 various269.28 biosafety,269.76 requirements,271.14 and,272.35 the272.82 part273.46 of273.63 the273.79 permitting273.87 and274.26 the274.43 activities274.58 that275.06 that275.23 happen275.46 in275.7 the275.87 lab.275.94 So277.79 maybe278.02 I278.26 thought278.43 it278.5 was278.58 just278.75 a278.9 very278.9 high279.14 level,279.38 and279.94 I280.1 think280.19 I280.43 alluded280.66 to280.99 that.281.22 What282.1 we282.26 specialize282.43 in282.99 is283.22 integrating283.46 computational284.96 methods285.6 to286.16 enable286.32 scientists286.64 to287.04 make287.2 better287.36 decisions287.6 as288.64 to288.72 the288.96 molecules289.12 that289.6 they're289.76 going289.92 to290.24 become,290.24 drugs.290.8 So291.12 that291.28 allows291.52 us291.84 to292 bring292.16 new292.64 medicines292.88 to293.36 patients293.52 faster.294 And296.48 so,296.72 we298.47 have298.88 been299.19 headquartered299.51 or300.15 incubated300.95 in,301.6 in302 the302.24 Seaport302.47 area302.95 at303.68 451303.75 D304.56 Street,304.63 and305.91 we306.07 are306.24 in306.95 the307.12 process307.19 of308 relocating,308.24 to309.75 the310 current310.15 facility310.39 in312.15 Watertown.312.31 So312.95 this313.12 is313.27 66313.35 Gallon314.58 Street314.9 on315.22 the315.38 Second315.54 Floor.315.78 316.34 This316.34 is316.58 where316.66 I'm316.82 taking316.98 the317.3 call317.38 today,317.7 actually.318.02 It's319.46 a319.78 total319.94 space320.26 of320.58 about320.82 18,000321.22 square322.02 feet322.26 that322.5 comprises322.74 both323.38 offices323.7 as324.18 well324.34 as324.58 labs.325.14 And326.82 as327.06 I327.22 highlighted,327.38 we327.86 just328.02 walked328.26 into328.5 the328.82 space.328.98 And329.3 to330.14 your330.19 point,330.23 we330.7 are330.94 looking331.19 for331.5 the331.75 final331.99 approval333.19 so333.67 that333.82 we333.9 can333.99 initiate334.31 our334.79 lab335.26 work.335.5 I337.67 just337.9 wanted337.9 to338.14 highlight338.31 some338.63 of338.87 the338.94 key339.1 features339.9 of340.31 the340.38 building340.54 first.340.94 This341.58 is341.92 a342.24 brand342.4 new342.72 building.342.8 It's343.12 a343.36 spec343.44 suite.343.68 As343.92 I344.08 mentioned,344.16 we344.48 did344.64 no344.8 construction345.44 or345.92 renovations.346.08 The347.52 building348.4 is349.04 state349.04 of349.28 the349.44 art.349.6 There349.84 is350.08 a350.24 key350.24 card350.4 restricted350.8 out,351.84 access.352.24 Also353.76 within355.84 business356.16 hours,356.48 actually.356.88 Our359.29 company359.37 space359.76 is360.08 also360.25 keycard360.49 restricted360.96 24/7.362 And363.37 the363.52 access363.69 is364 provided364.32 only364.96 to365.2 train365.29 and365.6 authorize365.69 individuals366.16 particularly366.64 when367.13 it367.29 comes367.37 to367.6 accessing367.85 the368.16 labs.368.4 And369.6 all369.76 visitors370 must370.56 sign370.81 in371.04 at371.13 the371.29 entry.371.44 371.76 There371.76 is372 a372.08 security372.43 guard372.75 outside,372.91 and374.03 there374.19 are374.43 no374.59 visitors374.83 that375.23 are375.39 allowed375.55 in376.03 the376.19 laboratory376.35 unless377.15 they're377.55 escorted377.79 by378.43 our379.15 staff,379.39 and379.63 that379.79 includes,380.03 staff,381.31 technical381.95 staff382.43 that382.67 is382.83 responsible,383.07 for383.55 example,383.71 for384.03 installing384.19 or384.67 maintaining384.83 equipment.385.23 So387.63 this387.88 is388.12 the388.19 view388.51 of388.92 the389.39 overall389.56 footprint.390.44 You're392.12 seeing392.44 some392.75 of393 the393.07 various393.24 RFI393.8 access394.36 points.394.68 Just395.8 wanted395.95 to396.36 highlight,396.44 again,397.8 this398.04 is398.27 a398.44 new398.6 building,398.83 so399.15 state399.39 of399.63 the399.71 art399.88 HVAC,400.19 and401.07 air401.31 supply.401.56 It's403.37 100%403.69 outside404.41 air,404.89 and405.13 there405.29 is405.53 no405.61 circulation405.77 between406.49 the406.89 lab406.89 and407.13 offices.407.29 All409.45 lab409.85 areas410.09 are410.57 BL2.411.29 We412.65 have412.81 a412.97 dedicated413.13 area413.77 in414.09 the414.17 lab414.33 for414.65 hazardous414.97 waste.415.93 And417.29 all417.69 of417.85 the418.01 fire418.18 extinguishers418.5 and419.06 eye419.29 washes419.54 have420.41 been420.57 installed420.74 as421.21 per421.38 code.421.54 In423.94 terms424.1 of424.41 the424.5 work424.65 that424.89 we425.06 do,425.21 we426.41 are426.57 currently426.74 focusing427.13 on427.62 a427.77 class427.94 of428.33 targets429.88 that430.44 is430.68 at431.4 play431.64 in432.68 the,433.72 for433.88 patients434.12 suffering434.44 from434.84 inflammation435 and435.56 autoimmune435.64 disease.436.12 436.6 These436.6 typically437.24 are437.72 addressed437.96 with438.36 injectable438.6 agents439.56 and439.96 what440.12 we're440.28 trying440.44 to440.68 offer440.84 to441.08 patients441.24 is441.64 already442.9 bioavailable443.3 equivalent.443.94 So444.42 pills444.65 instead444.98 of,445.3 of,445.9 needles446.81 and447.3 injectables.447.69 I449.69 spoke449.94 briefly450.25 about450.81 the451.06 technology451.22 that451.69 we451.86 use,452.01 but452.34 suffice452.65 to452.98 say453.22 that453.38 the454.1 work454.25 that454.5 we454.74 want454.9 to455.22 conduct455.22 in455.54 the455.62 lab455.78 and456.01 that456.18 we456.25 actually456.5 perform,457.06 is458.49 predominantly459.05 about459.61 building459.93 the460.25 tool460.41 systems460.73 so461.29 that461.53 we461.69 can461.77 test462.01 our462.25 small462.49 molecules,462.81 purify464.25 the464.73 proteins,464.89 and465.53 so465.77 forth.466.01 So466.33 this466.49 is466.73 very,466.89 I467.53 would467.69 say,467.93 a468.41 basic468.41 type468.81 of469.05 work469.21 that469.45 we469.69 do469.85 at470.01 the470.17 biochemistry470.33 level.471.05 And472.65 it's472.88 all473.13 pretty473.44 much473.69 part476.73 of476.81 the476.88 state477.05 of477.21 the477.29 art477.37 that477.69 is477.76 used478 in478.25 labs478.88 for479.21 the479.44 purposes479.61 of480.08 biochemistry480.25 or481.37 structural481.52 biology.482.08 And484 it's484.17 so484.32 it's484.49 all484.65 bench484.81 scale.485.05 There485.37 is485.52 no485.69 animal485.93 or486.32 plant486.49 work486.81 or487.05 production487.39 type487.55 of487.71 work487.95 that488.27 we488.35 do.488.51 489.63 I489.63 mentioned489.79 the490.19 BSL2490.91 type491.31 of,491.39 biosafety492.19 that492.91 we493.07 are493.31 conducting,493.71 and496.27 this496.43 pertains496.75 mainly497.39 to,497.79 working498.75 with499.15 primary499.31 cells,499.79 human500.03 cells,500.43 some501.94 work502.1 with502.42 the,502.57 non-replicating,503.86 lentiviral504.81 vectors,505.54 and,506.25 of506.5 course,506.57 a506.81 lot506.89 of507.06 BSL1507.62 type507.86 of508.01 work,508.18 that509.13 could509.3 also509.45 occur.509.86 The511.77 controls512.01 are,512.82 again,513.13 as514.1 per514.25 code.514.5 So514.74 we514.98 have515.05 class515.29 Two515.53 biosafety516.01 covenants,516.65 mentioned517.61 about517.85 the518.41 access518.81 restriction,519.13 the520.57 PPEs520.73 in521.29 place,521.45 the521.85 various522.09 decontamination522.33 protocols523.21 are523.85 in524.17 place,524.41 and524.65 we524.81 have524.97 waste526.01 disposal526.41 by526.89 professional527.05 companies527.53 that528.01 we've528.17 retained,528.65 and529.05 we'll529.13 touch529.37 on529.53 that529.69 later530.09 in530.41 the530.57 slides.530.65 And532.13 we've532.37 also532.61 put533 in533.25 place533.4 the533.73 various533.8 hazard534.13 and534.37 mitigation534.52 approaches,535.17 whether535.8 it's536.13 biological,536.37 for538.29 the538.45 primary540.21 human540.68 cells,540.92 blood,541.4 and541.88 recombinant542.21 cell543.57 lines.544.13 544.37 Whether544.37 it's544.37 chemical,544.52 and546.23 that546.47 includes546.71 strict547.19 PPE,547.67 fume548.31 hoods,548.63 autoclave,549.51 the550.87 various551.03 decontamination551.35 protocols,552.23 and,553.19 again,553.51 the553.91 regulated554.07 waste554.63 pickup,555.27 whether555.67 it's555.83 for555.99 chemical556.23 or556.63 biohazardous556.87 waste.557.67 So560.88 coming561.04 back561.45 to561.61 the561.76 overall561.85 biosafety562.25 summary,562.97 I563.92 touched564.09 on564.4 human564.88 cell565.29 lines,565.52 the567.04 third567.29 generation567.52 lentiviral568 vectors.568.73 So569.13 these569.37 are569.61 replication569.76 competent,570.33 again,570.88 tools571.21 that571.52 we571.68 use571.85 in572 the572.17 labs.572.33 Human573.58 blood573.9 but574.22 this574.38 is574.62 all574.86 obtained575.1 from575.42 commercial575.66 sources576.06 so576.54 that's576.7 from576.86 patients.577.02 And578.46 this,578.78 from579.26 commercial579.5 sources579.9 we're580.3 relying580.54 on,581.02 on,581.94 at583.02 least583.26 what583.5 we583.74 purchase583.9 are584.46 from584.7 healthy584.94 volunteers585.26 and585.98 these586.22 are586.46 already586.62 screened586.94 and587.26 tested587.42 for587.82 pathogens.588.06 A590.27 lot590.36 of590.6 the590.75 vectors590.92 that591.24 we591.39 use591.56 are,591.88 you592.44 know,592.6 ATCC,592.84 immortalized593.63 type594.12 of594.36 cell594.51 lines,594.75 as595.15 well595.24 as595.48 E.595.63 Coli595.8 for596.2 our596.36 recombinant597.08 DNA597.63 work.598.04 We599.72 have599.88 the600.04 biosafety600.27 manuals600.92 and601.39 exposure602.11 control602.43 plans603.15 that603.47 are603.63 already603.79 in604.03 place.604.19 604.91 These604.91 are605.15 available605.31 both605.79 as606.03 electronic606.35 as606.83 well606.99 as607.23 hard607.39 copies607.55 of608.03 the608.11 disposal608.27 of608.75 all608.83 of608.99 the609.07 employees.609.23 And611.55 we611.79 have611.87 a612.67 quality612.83 status613.15 safety613.63 committee.613.95 This614.51 is614.75 meeting614.91 now615.39 with615.55 a615.79 regular615.87 cadence.616.35 We617.21 have617.37 a617.45 biosafety617.68 officer.618.4 His618.81 name619.05 is619.21 Vishal619.29 Sinaba,619.68 who's620.17 one620.57 of620.88 our621.13 lead621.76 scientists.622.09 And623.37 all624 of624.09 the624.17 work624.33 practices624.57 are625.13 consistent625.29 with625.85 the625.93 virus626.09 requirements,626.49 the627.29 disinfection627.68 protocols628.4 approved629.82 by630.14 the630.3 EPA,630.54 and631.5 the631.74 biological631.9 waste632.46 disposal632.78 is,633.34 I634.14 mentioned634.22 commercial634.62 source,635.1 and635.26 that's635.42 Veolia.635.9 All637.5 of637.74 the637.82 employees638.06 undergo638.86 a639.34 comprehensive639.42 employee640.14 training640.46 as641.02 well641.18 as641.42 refreshers,641.66 And643.25 the643.49 recombinant643.8 DNA644.29 projects,644.76 again,645.33 are,645.64 subject646.37 to646.68 registration,646.85 part648.61 of648.85 the649 virus649.09 safety649.4 program,649.73 and650.21 the650.45 waste650.61 management650.92 is651.57 all651.8 reviewed651.88 and652.29 approved652.45 by652.85 the653 IPC.653.16 656.4 So656.4 in656.72 turn,656.8 this657.04 is657.2 just657.28 summarizing657.44 where658 we658.16 stand658.24 currently658.64 in659.12 the659.28 process.659.84 So660.32 the660.56 recombinant660.72 didn't661.28 work.661.52 That's661.92 still662.08 in662.32 progress,662.48 and662.88 this663.36 is663.6 why663.68 we're663.92 having664.08 that664.4 conversation.665.2 When667.88 it668.03 comes668.12 to668.27 the668.36 flammable668.6 permit669.08 and669.55 the669.72 lab669.96 registration670.12 per670.84 se,671 we671.63 finally672.43 completed672.84 the673.39 inspection673.63 by674.2 the674.36 Watertown674.51 fire675.63 department.675.96 The678.84 MWRA679.15 is,680.75 to681.48 the681.63 landlord.681.79 We682.8 have682.96 our683.52 MA684.72 DAP685.68 numbers,685.68 so686.24 it's686.32 all686.56 registered.686.8 I688.16 mentioned688.24 the688.56 manuals688.72 are689.12 in689.2 place.689.36 In690.64 terms690.8 of691.04 medical691.2 surveillance,691.68 that's692.24 going692.56 to692.8 be,692.8 we're693.68 retaining694.08 Mount694.48 Auburn694.56 for694.96 that.695.12 Occupational696.48 health,697.2 I698.21 mentioned698.37 and698.85 I699 touched699.17 on699.4 the699.49 training,699.64 and700.52 this700.76 will701 be701.17 again,701.4 conducted702.21 once702.68 the702.93 facility703.09 is703.57 occupied703.73 in704.29 terms704.45 of704.61 adapting705.4 to705.81 the705.97 new706.05 space.706.29 We707.73 have707.88 pest708.29 control,708.61 also,709.64 a710.61 vendor710.76 that's711.17 Buono711.49 Pest.711.88 And,713.14 again,713.86 we714.18 mentioned714.5 Ola715.06 in715.3 several716.1 instances.716.1 And717.14 so717.3 that's717.54 the717.78 overview718.02 of718.5 the718.98 company719.22 and719.62 where719.78 we720.02 stand720.18 and720.98 the721.14 various721.3 activities721.62 that722.02 we722.18 have722.26 put722.42 in722.66 place.722.74 And,726.34 yeah,726.65 I'm726.89 happy727.05 to727.38 take727.46 questions727.86 or728.25 to,728.5 yeah,728.82 to729.05 fill729.22 any729.46 questions729.62 or730.1 any730.25 discussions730.58 that730.98 you731.22 may731.38 have.732.5 734.25 AMIRTHARAJ734.25 -734.25 Thank734.25 you734.58 for734.65 the734.82 presentation.734.98 Jessica,736.89 do737.46 you737.62 have737.77 any737.93 questions?738.25 740.49 MALENFANT740.49 -740.49 No.740.49 I740.61 don't740.73 think740.97 so,741.21 actually.741.29 It741.53 was741.69 pretty741.85 thorough742.09 and742.33 covered742.49 things742.89 I743.05 would743.21 have743.37 asked,744.09 so744.49 nothing745.29 for745.61 me.745.85 Something746.25 a746.57 pretty746.73 straightforward,746.97 well748.57 organized748.81 group.749.21 750.09 SAYEGH750.09 -750.09 Thank750.09 you.750.41 751.69 AMIRTHARAJ751.69 -751.69 That's751.69 my752.01 only752.17 question752.33 would752.73 be752.89 with754.99 the755.14 initial755.31 permit755.79 request,756.19 were756.75 there756.99 plans757.14 for757.47 a757.71 Vibarium?757.87 759.23 SAYEGH759.23 -759.23 No.759.23 We759.63 have759.95 not761.31 had761.47 any761.79 plans762.02 or762.43 ambitions763.14 to763.63 have763.79 a763.87 Vibarium764.02 on-site.764.59 765.47 AMIRTHARAJ765.47 -765.47 Okay.765.47 So,767.43 Ms.767.67 Myers,768.07 I768.39 guess768.47 we768.63 wouldn't770.07 be770.31 doing770.47 a770.71 conditional770.87 approval771.35 regarding772.23 the772.79 application.772.95 Regarding774.07 the774.31 application.774.31 774.31 MYERS774.31 -774.31 Correct.774.31 774.31 AMIRTHARAJ774.31 -774.31 Okay.774.31 Alright.775.43 Motion775.99 to776.39 approve776.55 the777.19 permit,777.35 for778.07 Psivant778.87 Therapeutics780.15 780.15 MALENFANT780.15 -780.15 Second.780.15 780.15 Citing.781.28

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implement,2700.41 I2701.3 guess,2701.38 if2701.53 they're2701.69 only2701.93 allowed2702.41 to2702.73 sell2702.89 certain2703.3 packages.2704.17 Like,2704.65 are2704.73 they2704.89 blue2705.05 or2705.38 green?2705.53 Or.2705.86 2706.71 ELLIS2706.71 -2706.71 It's2706.71 not2706.95 super2707.11 challenging.2707.59 They2707.99 actually2708.15 have2708.39 the2708.55 milligrams2708.71 in,2709.19 like,2709.35 a2709.51 giant2709.67 letter2710.07 on2710.47 the2710.63 front.2710.79 Okay.2711.27 So2711.59 it's2711.75 really2711.91 easy2712.23 to2712.71 kind2712.95 of2713.11 see2713.35 how2714.07 many2714.31 milligrams2714.63 are,2715.11 like,2715.27 at2715.51 a2715.67 glance.2715.83 When2716.71 I2716.87 go2717.03 into2717.11 stores,2717.35 it's2717.67 really2717.91 easy2718.07 for2718.31 me2718.55 to2718.71 see.2719.19 2721.31 MALENFANT2721.31 -2721.31 Cool.2721.31 That's2721.63 actually2721.79 helpful2722.03 to2722.43 just2722.74 even2722.91 know2723.22 that.2723.39 Yes.2724.03 But2724.99 I2725.14 agree2725.22 with2725.55 Dominic.2725.63 I2725.95 think2726.03 I2726.27 don't2726.35 really2726.51 have2726.74 strong2726.99 opinions,2727.31 especially2727.7 as2728.18 we've2728.18 got2728.27 the2728.51 age,2728.66 if2729.31 we're2729.47 going2730.51 to2730.91 focus2730.91 on2730.91 the2731.14 next2731.47 gen2731.79 and2732.11 having2732.59 those2732.91 age2733.07 restrictions.2733.31 2734.35 MYERS2734.35 -2734.35 Okay.2737.83 Perfect.2738.47 Yeah.2739.11 And2739.43 I2739.67 can2739.75 put2739.99 notes2740.23 and2740.55 then2740.79 comments,2741.03 and,2741.43 again,2741.75 we'll2742.31 have2742.63 the2742.87 hearing2743.35 for2743.67 discussion.2744.47 Items2746.15 102746.95 through2747.43 14.2750.02 So2752.09 that2752.18 is2752.41 blunt2752.97 wrap,2753.38 banning2754.66 blunt2755.06 wraps,2755.3 banning2756.41 free2757.14 distribution2757.38 of2757.93 tobacco2758.18 products,2758.58 banning2759.61 redemption2760.18 of2760.66 coupons,2760.82 banning2761.45 self-service2762.09 displays,2762.89 and2763.78 banning2764.63 tobacco2765.03 sales2765.67 in2765.99 an2766.23 educational2766.55 institution.2767.35 We2768.23 all2768.71 do2769.11 have2769.43 that2770.47 as2770.79 yes2771.11 already,2771.51 so2772.07 we2772.39 would2772.47 need2773.75 no2773.99 changes.2774.23 And2778.11 then2778.26 it2778.59 goes2778.82 into2779.3 number2780.59 15,2781.7 which2782.34 is2782.59 the2782.91 fining2783.14 structure2783.63 system.2784.18 So,2785.22 we2787.63 could2787.86 do2788.11 the2790.11 fining2790.18 structure2790.66 that2792.61 we2792.77 have2792.93 in2793.01 the2793.09 regulations2793.41 already2794.05 for2795.01 the2795.17 local2795.33 ones.2796.77 And2797.17 then2797.33 any2797.73 state2798.13 regulations2798.69 that's2799.25 violating2799.57 would2801.89 be2802.13 the2802.69 state2802.93 fine,2803.33 or2803.81 we2804.05 can2804.21 combine2804.53 them2805.01 just2805.17 to2805.41 one2805.57 set2805.81 of2806.05 fines.2806.21 2809.66 ELLIS2809.66 -2809.66 Not2809.66 exactly.2809.99 I'm2810.47 sorry.2810.63 2811.11 MYERS2811.11 -2811.11 Oh,2811.11 sorry.2811.27 2812.14 ELLIS2812.14 -2812.14 No.2812.14 You're2812.63 okay.2812.79 So2813.43 the2813.91 state2814.14 fines,2814.47 no2814.95 matter2815.18 what2815.43 you2815.59 do,2815.74 it's2815.91 going2816.14 to2816.39 be2816.55 a2816.63 thousand2816.79 dollars2817.11 for2817.43 the2817.59 first2817.74 violation,2817.99 $2,0002818.7 for2819.51 the2819.66 second,2819.83 and2820.14 then2820.31 $5,0002820.55 for2821.59 the2821.83 third2822.07 and2822.31 fourth,2822.55 and2822.87 so2822.87 on.2823.11 So2824.28 for2824.6 your2824.76 local2824.92 violations,2825.24 you2825.8 can2825.88 adjust2826.12 those2826.52 to2826.84 make2827 them2827.24 either2827.72 hold2828.12 the2828.44 $100,2829.64 $200,2830.68 $3002830.68 or2830.68 make2831 them2831.24 a2831.48 blanket2831.48 $1,0002832.12 so2834.12 it's2834.36 a2834.68 little2834.84 bit2835.08 closer2835.32 to2835.72 those2835.88 the2836.36 state2836.51 level2836.76 fines.2837.23 You2838.19 are2838.51 also,2838.84 if2839.23 you2839.39 would2839.55 think2839.8 $1,0002840.11 across2841.07 the2841.39 board2841.55 might2842.03 be2842.28 a2842.36 little2842.43 bit2842.67 too2842.91 extreme,2843.07 you2843.88 can2844.11 increase2844.43 each2845.15 of2845.55 the2845.8 fines2846.84 incrementally.2847.47 I2848.28 know2848.36 that's2848.43 what2848.67 Stoughton2848.91 is2849.32 looking2849.47 at.2849.71 So2850.03 they're2850.28 increasing2850.51 from2851.6 $1002851.84 to,2852.32 I2852.56 think,2852.64 like2852.8 $2502853.36 for2854.08 the2854.24 first2854.4 fine2854.64 and2854.96 then2855.04 like2855.28 $5002855.44 and2855.92 then2856.08 for2856.24 the2856.4 third,2856.48 it's2856.72 $1,0002857.04 and2857.44 like2857.6 so2857.76 on,2857.92 after2858.08 the2858.32 third,2858.48 it's2858.72 $1,000.2859.04 You2859.92 just2860.08 can't2860.24 go2860.56 above2860.8 $1,000.2861.36 That's2861.76 the2862 cap2862.16 for2863.12 local2863.36 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so2900.61 selling2900.84 under2901.33 to2902.36 someone2902.45 under2902.84 212903.16 would2903.72 be2903.89 a2904.2 state2904.53 violation2904.84 where2906.05 if2907.27 they2907.51 sold2908.07 blunt2909.11 wraps,2909.51 that2910.07 would2910.39 be2910.63 a2911.03 city2911.27 violation.2911.51 2912.87 MALENFANT2912.87 -2912.87 Got2912.87 it.2913.11 2914.87 MYERS2914.87 -2914.87 So2914.87 the2915.11 more2915.27 severe2915.59 ones2915.91 will2916.23 always2916.47 hold2916.79 the2917.27 higher2917.59 fines,2917.99 but2918.47 it2920.11 depends2920.66 if2920.66 we2920.83 want2921.07 to2921.55 raise2923.7 the2924.11 local2924.66 fines.2925.07 2927.47 AMIRTHARAJ2927.47 -2927.47 What2927.47 is2927.7 it2927.95 right2928.11 now?2928.34 2931.22 ELLIS2931.22 -2931.22 $100,2931.22 $200,2932.43 and2932.43 $300.2932.66 2933.86 AMIRTHARAJ2933.86 -2933.86 Okay.2933.86 2935.97 MYERS2935.97 -2935.97 Reilly,2935.97 you're2936.37 the2936.61 best.2936.77 2937.81 ELLIS2937.81 -2937.81 I2937.81 try.2937.97 2941.49 AMIRTHARAJ2941.49 -2941.49 I2941.49 mean2941.57 I'll2941.73 be2941.97 okay2942.13 with2942.45 staying2942.61 as2943.41 is.2943.57 2947.91 MALENFANT2947.91 -2947.91 Yeah.2947.91 I'm2948.15 okay2948.23 with2948.55 that2948.71 too.2948.95 2951.67 MYERS2951.67 -2951.67 Perfect.2951.67 Okay.2951.99 So2952.32 separate.2953.99 And2957.51 then2957.91 there2958.32 are2958.63 tolling2959.59 periods2960.15 for2960.84 local2961.08 violations,2961.4 and2962.28 I'm2962.44 so2962.6 sorry2962.84 I2963.08 keep2963.16 putting2963.4 you2963.64 on2963.8 the2963.96 spot.2964.12 But,2964.44 Reilly,2964.68 can2965 you2965.16 explain2965.4 the2965.8 tolling2966.04 violations?2966.44 2967.4 ELLIS2967.4 -2967.4 Of2967.4 course.2967.48 No.2967.8 I'm2967.96 happy.2968.44 That's2968.76 why2968.92 I'm2969.08 here.2969.24 So2970.2 that's2970.6 just2970.92 the2972.2 amount2972.68 of2973 time2973.16 for,2973.8 like,2974.28 a2974.78 first2974.93 violation2975.09 reset2975.82 of2976.22 sorts.2976.38 So2976.78 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seven3042.82 14,3042.82 and3042.82 third3043.22 is3045.53 seven,3046.34 143046.34 or3046.34 30.3046.57 Reilly,3055.85 is3056.49 this3056.81 for3057.29 the3058.17 suspension3058.41 periods?3059.13 Is3059.93 this3060.17 for3060.17 state3061.93 or3064.05 local?3065.65 3065.65 ELLIS3065.65 -3065.65 So3066.14 that3066.38 would3066.53 be3066.78 for3067.17 state3068.21 violations,3068.61 I3069.17 believe.3069.41 So3070.21 when3070.38 it's3070.53 a3070.78 sale3070.93 to3071.26 a3071.41 minor,3071.57 there's3072.38 like3072.69 a3072.93 slight3073.17 discrepancy.3073.49 When3073.97 it's3074.14 a3074.3 sale3074.38 to3074.61 a3074.78 minor,3074.86 the3075.26 suspension3075.41 can3075.89 be3076.05 anywhere3076.21 from3076.78 one3077.76 to3078 303078.24 days3078.64 for3079.2 a3079.44 sale3079.6 to3079.84 a3080 minor.3080.16 Typically,3080.48 people3080.88 will3081.2 go3081.44 ahead3081.6 and3081.76 pick3081.92 out3082.16 those3082.4 smaller3082.8 amounts.3083.12 So3083.6 like3083.84 the3084.08 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4110.72 Dominic4110.72 Mitraj?4111.52

4112.64 Aye.4112.64

4114.56 Jessica4114.56 Malafont?4115.04

4116.34 Aye.4116.34 Perfect.4117.94