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address.206.47 Okay.214 Seeing214.56 no214.96 public215.19 comment215.59 or216.07 question,216.79 we217.75 will218 get218.16 right218.4 to218.56 it218.72 then.218.88 So220.97 up221.29 next,221.53 number221.85 four,222.09 we222.49 have222.73 a223.05 permanent223.21 application223.77 for.224.49 And225.53 so225.85 my226.49 apologies226.73 if227.13 I227.29 mispronounced227.45 that.228.17 And,228.49 Zane,228.97 I229.45 believe229.53 you230.49 are230.73 the231.05 representative,231.21 the232.01 only232.25 person232.57 employed233.05 there233.45 in234.19 running234.44 the234.92 show.235.07 So235.47 thank235.63 you235.79 for236.03 being236.19 here236.44 this236.59 evening.236.84 237.79 ZANE237.79 JAAFAR237.79 -237.79 FLAGSHIP237.79 PIONEERING237.79 -237.79 Thank237.79 you237.96 all.238.12 And,239.16 yes,239.4 that239.72 is239.96 it.240.12 242.92 PARSONS242.92 -242.92 Yeah.242.92 I243.24 knew243.4 something243.56 was243.88 up244.03 when244.19 I244.35 opened244.51 up244.84 your244.92 biosafety246.91 committee247.63 minutes,248.75 and249.15 everyone249.47 was249.87 a250.03 community250.19 member.250.67 So252.19 I252.35 quickly252.51 went252.91 to253.31 your253.55 which255.47 one255.63 is255.87 it?256.03 The256.27 workers'257.15 affidavit257.63 and258.35 saw258.51 the258.75 big258.91 one259.15 there.259.39 So259.63 you262.73 have262.96 my263.2 admiration.263.44 So,264.49 do264.64 you264.88 have264.96 something265.37 to265.69 present,265.85 like266.32 a266.49 deck,266.64 or266.96 are267.37 you267.52 here267.69 to267.93 speak?268.08 269.6 JAAFAR269.6 -269.6 I269.6 was,270 I270.73 guess,270.81 advised271.04 to271.52 do271.85 some272.08 speaking,272.25 just272.64 generally272.88 about273.29 the273.52 plan274 and274.25 the274.4 work274.49 going274.73 on,274.96 if275.13 that's275.29 okay.275.52 276.37 PARSONS276.37 -276.37 Yeah.276.37 Sometimes277.09 people277.49 also277.97 have278.21 a279.09 slideshow279.33 to279.73 show279.81 as280.05 well,280.13 but280.37 it's280.61 not280.93 required.281.33 Can283.65 you283.73 just283.81 give283.97 us284.13 an284.29 overview284.45 of,284.85 what285.09 what285.25 you're285.41 doing285.65 here285.81 in285.97 Watertown?286.13 286.85 JAAFAR286.85 -286.85 Yeah.286.85 Totally.287.09 No288.81 one288.88 can288.88 see289.05 me.289.2 Right?289.37 There's289.85 this290.32 is290.49 the290.73 setting290.88 of291.2 the291.37 meeting.291.44 Right?291.76 Okay.291.93 Cool.292.25 Correct.293.05 Well,293.85 then294 I294.25 will294.32 just294.49 go294.73 for294.81 it.294.96 So,295.2 let295.61 me295.69 run295.85 through296 this.296.17 If296.32 you296.56 want296.64 me296.81 to296.96 speed297.2 up297.37 or297.52 expand,297.76 please298.17 let298.64 me298.81 know.298.96 But299.13 my299.76 name299.93 is300.08 Zane300.25 Jafar.300.4 Synema301.39 Incorporated301.95 is302.43 a302.59 company302.67 that302.91 I302.99 founded303.15 recently,303.47 and304.19 expect304.59 to305.47 commence305.63 lab306.11 operations,306.35 pretty307.31 soon,307.55 in307.79 Cambridge308.03 Scientific308.51 Lab,308.99 a309.71 private309.71 incubator310.03 suite.310.51 We311.87 intend312.03 to312.35 start312.51 operations312.75 at313.31 the313.39 site313.55 at313.71 200313.79 Dexter314.19 Ave,314.59 with315.07 the315.23 BSL315.39 one315.79 designation316.03 for317.56 all317.64 work,317.94 and318.25 we'll318.54 start318.7 operations318.86 as319.02 soon319.18 as319.33 we319.49 have,319.65 any,319.96 go320.93 with321.32 the,321.4 with321.81 the321.88 permitting.321.96 The323.49 company323.64 is323.96 being324.13 formed,324.37 ultimately325.16 to325.56 develop325.64 advanced326.04 technologies326.69 to327.25 manufacture327.32 large328.13 and328.29 complex328.37 DNA,328.93 and329.32 to329.49 do329.64 so329.81 without330.04 what330.63 is330.87 sort331.03 of331.11 industry331.43 standard331.83 dependence332.15 on332.55 large332.71 volume332.95 bacterial333.35 fermentation.333.91 And335.51 our335.83 technology336.15 has336.55 applicability336.79 to337.59 improvements337.83 for338.39 user339.35 experience,340.15 disease340.39 biology340.71 research,341.75 and342.39 the342.39 development342.55 of343.03 advanced343.19 cell343.8 and344.04 gene344.12 therapies,344.28 which345 have345.71 particularly345.96 high346.44 DNA346.68 demands.347.07 Ultimately,348.75 I348.96 think349.15 what349.4 we349.56 can349.71 do349.88 is350.04 build350.68 a352.19 way352.28 to352.68 decrease352.92 the353.4 need353.56 of353.8 our353.88 community354.04 members354.51 and354.92 customers355.56 to356.51 have356.68 hands-on357.24 time357.57 and357.81 resources357.97 devoted358.53 to358.93 growing359.09 bacteria359.41 in359.97 their360.05 labs,360.21 and360.85 things361.49 of361.81 that361.89 nature.362.05 364.13 And364.13 the364.45 way364.61 we364.77 plan364.93 to365.17 do365.33 this365.41 is365.57 through365.89 some366.21 more366.37 biotechniques,366.53 protein367.73 biochemistry,368.13 the368.93 use369.09 of369.33 laboratory369.57 strain370.21 E.370.53 Coli,370.69 to372.13 purify372.29 proteins,372.76 to373.64 make373.88 molecular374.29 systems,374.93 to375.49 amplify375.64 DNA.376.13 All377.08 this377.32 is377.49 planned377.56 to377.88 be378.29 carried378.37 out378.69 in378.76 accordance378.93 with379.32 local379.49 biosafety379.81 regulations,380.37 and381.81 is382.69 sort382.69 of382.85 represented383.08 by383.56 biosafety384.13 and384.61 chemical384.76 hygiene385.08 plans385.49 generated385.88 with386.37 Cambridge387.46 Scientific387.94 and,388.42 through388.98 Spotlight389.22 Solutions.389.7 With392.26 respect392.5 to392.74 biological392.98 inventory,393.62 the394.26 only394.34 organisms394.58 we395.22 have395.46 on395.78 deck395.94 to396.26 use396.5 are396.9 E.397.46 Coli.397.62 And398.5 there's398.74 largely399.14 k399.62 12399.78 strain400.1 derived400.58 E.400.9 Coli,401.14 but401.54 we401.87 also402.02 plan402.26 to402.35 use402.5 b402.99 strain403.38 derived403.7 b404.1 l404.26 21404.43 lineage404.9 organisms405.54 to406.99 produce407.22 protein.407.54 And407.94 that's408.1 ultimately408.35 why408.9 I'm409.22 here409.46 for409.7 this:409.87 a410.43 higher410.43 risk410.66 designation410.9 is411.38 because411.54 of411.79 the411.87 B412.02 strain412.19 used412.5 for412.66 protein412.82 expression.413.14 In414.56 addition414.8 to414.96 that,415.2 we416.4 plan416.64 to416.96 use,417.12 recombinant418.4 DNA418.96 as419.36 well,419.44 and419.6 this419.84 recombinant420.08 DNA420.56 is420.96 largely421.12 gonna421.44 take421.68 the421.84 form422 of,422.16 you423.6 know,423.84 plasmid424.16 DNA424.64 vectors424.96 for425.44 making425.6 and425.92 purifying426.16 proteins426.64 within427.12 these427.44 these427.76 E.428 Coli428.08 sourced429.16 from,429.4 from430.13 contract430.37 manufacturers,430.85 all,432.04 from433.16 nonpathogenic433.72 sources,434.52 nonviral434.93 sources,435.56 and435.96 all436.6 sequences,436.93 either437.72 wild438.13 type438.37 or438.6 engineered,438.76 ultimately439.49 from440.04 risk441 group441.32 one441.56 or441.81 BSL441.96 one442.52 type,442.76 organisms443.71 and444.27 sequences.444.43 Yeah.447.71 448.27 So448.27 ultimately448.51 and448.83 explicitly,449.39 I449.95 guess,450.11 what450.43 we're450.59 not450.75 doing450.91 is451.15 we're451.23 not451.39 working451.55 with451.79 pathogens.451.87 We're452.35 not452.59 working452.75 with453.07 anything453.55 infectious454.03 to454.51 humans,454.67 or455.63 select455.87 agents,456.19 or456.51 anything456.59 like456.91 that.457.07 And,459.53 related460.5 to460.81 the460.89 work460.97 we're461.21 going461.38 to461.53 be461.62 doing,461.77 as462.5 I462.74 mentioned,462.89 using463.38 recombinant464.33 DNA464.89 to466.97 express467.13 proteins467.53 in468.09 bacteria.468.5 And469.77 these469.94 bacteria470.18 will470.65 then470.89 be471.06 cultured472.16 in472.64 small-scale,473.52 small473.92 volumes,474.16 relatively475.36 small475.92 volumes476.16 under476.56 a476.88 few476.96 liters477.2 to477.68 make478.24 protein,478.48 isolate479.36 the479.76 protein,479.84 and480.32 reconstitute480.48 molecular481.36 sorts482.16 of482.32 systems482.48 to482.88 amplify482.96 DNA,483.36 all484.56 using484.96 or486.49 excuse486.56 me,486.88 biological-based488.81 buffers489.13 or489.52 biologically489.69 compatible490.17 buffers,490.73 non-hazardous491.85 additives492.96 in493.61 the493.76 forms493.85 of494.17 salts494.25 and494.56 things494.73 like494.88 that.495.05 So,496.65 nothing497.05 crazy497.37 is497.76 going497.76 on498 there.498.17 Yeah.500.99 And501.31 so501.55 related501.71 to502.11 all502.27 the502.43 chemicals502.59 and503.07 the504.19 waste504.35 generated504.75 with505.23 this,505.39 the505.71 large506.27 majority506.59 of507.15 the508.27 waste508.43 we508.67 plan508.83 to509.07 generate509.15 is509.55 liquid509.95 waste510.27 in510.51 the510.59 form510.75 of510.99 biological511.07 buffers511.63 through512.03 liquid512.67 chromatography513.07 for513.79 protein513.95 purification,514.27 salts,515.95 Tris516.83 buffers,517.14 things517.54 like517.78 that.517.87 And,519.07 any519.63 biomass520.66 in521.23 the521.38 form521.47 of521.71 bacterial521.87 culture522.42 or,522.83 of,523.95 bacterial524.66 lysates525.14 will525.78 be525.95 disposed526.11 of,526.5 after527.07 bleach527.63 decontamination,528.02 with529.76 appropriate530.56 contact530.96 times531.28 of531.6 20531.84 plus532.08 minutes532.24 in532.56 bleach532.72 before533.04 being533.36 disposed533.76 of534.16 down534.24 the534.4 drain.534.48 535.68 Any535.68 of535.92 the536.08 solid538.32 waste538.64 generated538.88 from539.28 this539.44 is539.76 going540.32 to540.56 be540.64 taken540.8 care541.12 of541.28 through541.92 the543.09 Cambridge543.33 Scientific543.88 contract544.37 with544.92 Veolia546.04 for546.68 waste546.92 disposal.547.16 And,548.52 they549.8 will549.97 also550.13 handle550.37 any550.68 of550.85 our551.09 chemical551.4 disposal551.8 or552.21 chemical552.37 waste552.68 disposal,552.85 which553.33 we553.49 don't553.64 plan553.97 to554.28 or554.61 we554.97 don't555.05 expect555.21 to555.79 be555.98 a556.17 frequent557.37 thing,557.69 as557.85 most558.01 of558.25 what558.33 we'll558.41 be558.65 doing558.73 again558.97 are559.29 non-hazardous560.01 chemicals,560.57 in561.37 protein562.09 solutions.562.49 Veolia564.49 is564.97 also565.13 responsible565.37 for565.85 dealing566.99 with567.3 our567.46 sharps567.54 and567.87 chemical568.02 waste568.35 as568.54 well,568.75 on570.02 as570.26 needed.570.5 Excuse570.9 me.571.14 Yeah.571.54 Sharps571.87 and572.02 glass572.18 waste572.42 are572.75 needed572.9 as573.14 well.573.3 All574.35 this574.5 work574.75 is574.99 going575.23 to575.54 take575.63 place575.78 in576.18 the577.07 Lab577.63 Suite,578.02 Lab578.5 C,578.83 at579.14 Suite579.38 260,579.63 Cameron580.81 Scientific.581.13 It's582.01 all582.17 BSL582.41 one582.81 designated583.37 work584.01 with584.73 the584.97 PPE585.61 recommended,586.33 there586.81 being587.29 lab587.53 coats,587.85 gloves,589.53 and590.01 eyewear,590.25 with591.45 bacterial591.85 work592.41 taking592.57 place592.81 within593.21 the593.53 suite593.61 and593.85 throughout594.01 the594.33 suite,594.41 but594.95 the595.11 suite595.26 itself595.31 is595.35 separate596.07 and596.54 sectioned596.87 off597.26 from597.5 the597.66 rest597.75 of597.99 the598.14 communal598.71 spaces599.11 or599.42 lab599.59 spaces599.83 in600.3 the601.18 rest601.35 of601.5 the601.66 facility.601.83 Yeah.605.11 605.35 And605.35 so,605.5 if606.3 there606.54 are606.71 any606.87 issues,607.18 we607.66 do607.83 have608.07 a608.3 biosafety608.87 manual,609.5 chemical610.22 hygiene610.54 plan,611.02 as611.26 well611.42 as611.66 an611.82 emergency611.82 response612.38 plan612.78 in613.1 place613.26 through,614.06 sort615.02 of615.18 work615.34 with615.66 Cameron615.9 Scientific616.3 Labs616.62 as616.94 well617.02 as617.18 Spotlight617.34 Solutions617.74 to618.7 handle618.86 any619.26 issues619.42 related619.82 to,620.22 you621.42 know,621.5 things621.66 of622.15 the622.32 nature622.48 of622.63 spills622.8 or623.36 exposures623.68 or,624.15 chemical624.72 exposures625.12 and625.68 the625.75 like.625.84 And626.39 any626.56 issues626.8 that627.12 we627.27 have627.36 will627.51 be627.68 handled628.08 by628.48 Mount628.88 Auburn629.12 Occupational629.51 Health,630.08 with630.32 which630.32 we630.56 already630.63 have630.88 our631.04 relationship631.51 set632.63 up.636.86 Ultimately,636.86 I'm637.34 the637.9 army638.38 of638.7 one638.86 as639.34 of639.5 right639.66 now.639.82 So640.06 the641.66 biosafety641.9 officer642.46 is643.1 me,643.26 and643.5 I'll643.58 be643.74 responsible643.9 for644.54 taking645.18 and646.46 tracking647.66 all648.06 the648.22 training648.3 and648.7 otherwise,649.02 but649.5 that's649.74 already650.32 set650.63 up650.71 to650.88 be650.95 recorded651.27 appropriately,651.83 according652.79 to653.27 the653.43 systems653.75 that654.15 we've654.32 put654.55 in654.79 with654.95 contract656.95 work657.36 from657.6 Spotlight657.75 Solutions.658.15 And659.6 that's660 sort660.48 of660.71 the660.79 gist.660.95 If661.2 there661.27 are661.43 any661.51 questions,661.67 I'm662 happy662.15 to662.39 answer.662.48 664.5 PARSONS664.5 -664.5 Great,664.5 Zane.664.82 Thank665.06 you665.22 very665.38 much.665.54 I668.26 will668.5 go668.74 left669.86 to670.1 right670.26 here.670.42 So,670.74 Mia,671.06 any671.38 questions671.54 for671.94 Zane?672.18 674.34 LIEBERMAN674.34 -674.34 Nope.674.34 This674.58 is674.82 very674.98 straightforward.675.3 Thank675.86 you.676.02 677.01 JAAFAR677.01 -677.01 Thank677.01 you.677.17 678.29 PARSONS678.29 -678.29 Ralph.678.29 679.5 RALPH679.5 MELE679.5 -679.5 BIOSAFETY679.5 COMMITTEE679.5 MEMBER679.5 -679.5 No679.5 questions.679.82 681.58 PARSONS681.58 -681.58 Deb.681.58 683.74 DEBORAH683.74 MCEWAN683.74 -683.74 BIOSAFETY683.74 COMMITTEE683.74 MEMBER683.74 -683.74 Well,683.74 thank684.05 you684.22 for684.38 the684.53 walk-through.684.93 It685.25 was685.34 very686.29 thorough.686.7 I686.86 don't687.01 have687.1 any687.25 questions687.41 about687.89 the688.29 science688.46 part,688.93 but689.17 if689.41 you689.58 are689.82 a690.05 company690.13 of690.53 one,691.34 is691.55 there691.63 ever691.79 a691.87 time691.95 you692.27 would692.43 be692.59 working692.75 alone693.23 in693.87 the694.11 area,694.19 or695.71 are695.95 there695.95 any695.95 concerns?696.11 696.35 JAAFAR696.35 -696.35 You696.35 mean696.67 throughout697.07 the697.31 building697.39 or697.63 just697.79 within697.95 the698.19 lab698.35 suite?698.59 699.47 MCEWAN699.47 -699.47 Right.699.47 Like,699.63 well,699.79 either,701.15 I701.71 guess.701.87 Yes.702.27 703.47 JAFAAR703.47 -703.47 There704.99 is705.3 a705.47 likelihood705.54 of705.95 that706.02 certainly706.18 within706.5 the706.75 lab706.83 suite.707.07 I707.47 think707.63 it's707.79 probably708.35 pretty708.75 rare708.9 that709.14 it709.3 would709.38 be709.54 without709.63 throughout710.18 the710.42 building,710.59 but,710.99 yeah,711.3 that's711.54 what712.42 will712.5 be712.75 happening.712.83 713.54 MCEWAN713.54 -713.54 Okay.713.54 No717.33 particular717.49 concerns.717.89 I718.29 mean,718.37 it's718.45 written718.77 out719.01 by719.17 safety.719.33 I719.73 just719.81 wanted719.97 to720.85 call721.01 that721.25 out.721.41 722.05 JAAFAR722.05 -722.05 Yeah.722.05 I'm722.37 happy722.61 to722.93 take723.09 any723.25 recommendations723.57 on,724.13 if724.53 there's724.69 anything725.01 I725.25 should725.41 be725.57 doing725.81 with726.13 respect726.29 to726.61 that,726.77 but726.93 that's,727.17 unfortunately,727.89 the728.37 nature728.45 of728.69 the728.85 beast728.93 right729.09 now.729.33 732.88 PARSONS732.88 -732.88 Thank732.88 you,733.13 Deb.733.37 Tim,733.92 any734.25 questions734.49 for734.88 Zane?735.13 736.88 MAGUIRE736.88 -736.88 No.736.88 None737.21 for737.45 me.737.61 Thanks.737.76 739.21 JAAFAR739.21 -739.21 Thank739.21 you.739.45 740 PARSONS740 -740 Okay.740 Well,740.73 I741.04 can't741.21 make741.45 motions741.61 anymore,742 so742.96 I743.37 still743.52 did743.76 it743.92 for744.16 the744.33 acceptance746.02 of746.34 the746.42 minutes.746.58 I747.06 don't747.22 really747.46 know747.94 what.748.74 So,748.74 someone749.62 else750.02 will750.18 need750.34 to750.5 make750.58 a751.22 motion751.3 that753.22 the753.46 Watertown753.62 Biosafety754.18 Committee754.74 recommends756.1 the756.66 permit756.9 for758.02 approval758.18 to758.74 the759.06 board.759.62 767.12 MCEWAN767.12 -767.12 I767.12 move767.36 that767.6 we767.92 recommend768.15 the769.04 permit769.27 of770.63 sitnum770.88 with773.27 the774.15 submission774.63 as774.63 is,774.88 for775.43 BordaPal.775.75 775.75 LIEBERMAN775.75 -775.75 Seconds.777.94 780.74 PARSONS780.74 -780.74 Any780.74 further780.98 discussion?781.46 Alright.782.82 Seeing783.3 none.783.62 Maureen,784.1 can784.42 we784.58 please784.74 take784.98 a785.14 vote?785.22

788.5 SPEAKER7788.5 -788.5 Yes.788.5 Mia790.78 Lieberman?791.18

792.07 SPEAKER5792.07 -792.07 Yes.792.07

793.11 SPEAKER7793.11 -793.11 Brad793.11 Parsons?793.58 Yes.794.63 Deb795.18 McEwen?795.58

796.46 SPEAKER4796.46 -796.46 Yes.796.46

797.35 SPEAKER7797.35 -797.35 Tim797.35 McGuire?797.66 Yes.799.35 Ralph800.54 Mele?801.02

801.82 SPEAKER8801.82 -801.82 Yes.801.82

804.28 PARSONS804.28 -804.28 Great.804.28 Thank804.68 you.804.92 Alright.805.16 So,805.48 Zane,805.8 the806.12 next806.2 step806.44 for806.76 you806.92 is807.32 to807.72 present807.8 to808.12 the808.28 board808.44 of808.68 health808.76 because808.92 we809.08 don't809.24 actually809.48 give813.64 out813.8 the814.04 permits.814.28 So816.36 I'm817.24 pulling817.48 up817.72 my817.88 calendar818.04 here.818.52 819.77 MAUREEN819.77 FOLEY819.77 -819.77 CITY819.77 OF819.77 WATERTOWN819.77 -819.77 I819.77 think819.86 it's820.1 the820.34 eighteenth.820.5 821.54 PARSONS821.54 -821.54 Yeah.821.54 So,823.62 february824.23 18.824.23 That's826.01 the826.25 board826.42 of826.65 health826.74 meeting,826.89 and827.13 so827.38 that's827.62 gonna827.86 be828.18 the828.34 same828.5 kind828.82 of829.05 thing.829.13 They829.93 may830.1 ask830.25 you830.5 what's830.65 going830.89 on,831.13 you831.13 know,831.3 kind832.01 of,832.34 a833.76 little834.36 more834.6 on834.76 the834.84 science835 side,835.32 a835.64 little835.72 less835.96 on836.2 the,836.36 you836.68 know,836.84 have837 to837.16 get837.24 into837.32 the837.72 VOA837.88 details838.28 and838.76 stuff838.84 like839.16 that839.24 with839.48 the839.64 board839.8 of840.04 health840.12 that840.52 more840.76 about843.64 the843.64 E.843.8 Coli843.96 and844.36 stuff844.52 like844.76 that,844.92 if845.16 they,845.32 you845.56 know?845.72 So,846.35 nonetheless,846.75 thank847.87 you848.11 for848.26 being848.42 here.848.66 Best848.99 of849.23 luck849.38 with849.54 your849.7 research.849.95 You850.42 are850.58 free850.82 to851.07 go.851.14 We851.38 will852.18 not852.5 be852.66 insulted852.9 if853.54 you853.7 drop854.82 off.855.14 855.95 JAAFAR855.95 -855.95 Alright.855.95 Perfect.856.26 Thank856.5 you856.66 all856.82 for856.99 your857.14 time.857.23 Appreciate857.46 it.857.87 858.5 PARSONS858.5 -858.5 Take858.5 care.858.75 Okay.864.45 Next865.09 up,865.57 we865.97 have866.45 amendments.867.89 So869.01 I870.93 have871.09 Parallel872.05 Biosystems,872.69 and874.68 I875.49 believe875.73 let876.13 me876.21 pull876.45 up876.61 my876.76 notes.876.92 This877.33 one877.57 is877.88 due879 to880.76 an880.85 expansion.881.08 So884.85 for885.4 the885.64 committee,885.96 this886.52 is886.68 BTP886.92 282888.56 if889.68 you're890 on890.48 OpenGov.890.88 Alright.895.76 So899.6 sorry.900 I900.48 don't900.64 have900.88 my901.12 normal901.28 setup901.84 this902.5 evening,902.74 so903.13 I'm903.38 minimizing903.62 screens904.33 and904.65 trying904.89 there905.13 we905.29 go.905.38 Back905.62 to905.86 Zoom.906.1 Alright.906.98 So,907.21 is909.45 someone909.7 here910.01 from910.17 Parallel?910.33 918.75 LIEBERMAN918.75 -918.75 Are918.75 we918.91 having919.15 two919.39 meetings919.39 in919.71 a919.87 row?919.95 924.11 JAYNES924.11 -924.11 Hi.924.11 Sorry.924.51 Can925.15 I925.15 talk?925.95 I926.19 thought926.27 there's926.51 gonna927.23 be927.55 someone927.79 else928.11 who's928.96 gonna929.12 be929.36 doing929.6 the929.84 talking.930.88 933.91 PARSONS933.91 -933.91 Surprise.933.91 Okay.935.43 So,942.38 I'm942.38 sorry.942.62 I'm942.86 just943.02 like943.34 I943.58 said,943.66 I'm943.82 not943.98 I944.22 don't944.3 have944.46 my944.62 normal944.78 setup945.1 here.945.42 So,945.74 alright.948.06 So,948.3 for948.54 an948.7 amendment,948.86 so949.26 I949.42 don't949.58 wanna949.74 put949.98 you950.14 on950.3 the950.38 spot.950.54 Are951.02 you951.18 prepared,951.34 like,951.9 with952.14 the954.08 discussion,954.48 or954.48 should954.71 we954.79 just954.96 jump955.43 to955.75 questions?955.91 958.63 JAYNES958.63 -958.63 Yeah.958.63 I959.03 mean,959.12 I959.36 don't959.43 know959.67 if960.96 I962 can962.24 discuss962.39 a962.79 little;962.88 there's963.51 not963.83 too964.15 much964.32 to966.93 go967.17 over967.33 just967.65 with967.97 the968.21 expansion.968.37 I968.85 think968.93 it's969.09 a969.41 continuation969.41 of970.13 all970.29 our970.53 regular971.57 work972.05 that972.37 had972.53 already972.77 been973.17 previously973.41 described.973.97 So974.37 if974.53 there974.69 are974.77 any974.85 questions,975.09 happy975.65 to975.97 answer.976.13 979.3 PARSONS979.3 -979.3 Okay.979.3 I'll979.54 start.979.87 I980.18 want.980.26 I980.5 only980.75 really980.99 have981.23 one,981.63 and982.02 it's982.18 about984.9 the985.14 floor985.23 plan,985.47 just985.78 so985.95 I986.11 can986.18 understand986.42 the990.18 expansion,990.42 and990.9 how991.14 are991.78 all992.42 of992.66 these992.83 suites993.14 not994.83 connected995.07 by995.55 doors?995.87 Like,997.07 you997.39 can't,997.55 can997.87 you998.03 go998.11 from998.27 Suite998.51 120998.75 directly1000.03 to1000.59 140?1000.67 1002.03 JAYNES1002.03 -1002.03 No.1002.03 They're1002.27 separate.1002.83 1003.79 PARSONS1003.79 -1003.79 Okay.1003.79 And1004.11 then,1004.27 so1004.51 what1004.75 about1004.83 so1005.71 and1007.51 then1007.75 Lab1008.63 3,1009.03 Lab1009.43 2,1009.83 and1010.07 Lab1010.32 1,1010.79 while1012 called1012.32 Suite1012.63 120,1013.03 are1013.67 they1013.83 also1014.07 separate1015.51 labs?1016 1018.71 JAYNES1018.71 -1018.71 So1018.71 yeah.1019.2 So1019.67 there1020.32 are1020.63 three1020.63 separate1020.63 lab1021.03 spaces.1021.36 1022.58 PARSONS1022.58 -1022.58 In1022.58 the1022.74 same1022.82 suite.1023.22 Okay.1023.46 Gotcha.1023.86 So1029.46 my1029.54 question1029.94 is1030.42 more1030.74 of1030.9 a1031.06 process1031.22 flow.1031.7 So,1032.5 like,1032.74 would1032.98 people1033.22 be1033.54 bringing1033.7 material1034.18 from,1034.66 say,1034.98 Lab1035.54 31036.18 to1038.52 Lab1039.72 21040.13 in1041.09 the1041.24 hallways?1041.57 1043.48 JAYNES1043.48 -1043.48 No.1043.48 There's1043.72 no1044.28 transfer1044.52 of1045 materials1045.09 between1045.57 the1045.88 lab1046.04 spaces1046.28 other1046.76 than,1046.92 like,1047.16 clean1047.88 autoclave1048.61 glassware.1049.24 But,1049.8 otherwise,1050.04 all1050.44 the1050.61 work1050.76 remains1051.44 in1051.76 the1051.92 lab1052.08 where1052.32 it1052.56 was1052.8 started.1053.28 1054.48 PARSONS1054.48 -1054.48 Okay.1054.48 Yeah.1055.12 I1055.76 could.1056 Yeah.1056.72 That1057.04 was1057.2 my1057.36 only1057.52 real1057.76 concern,1058.72 and1059.84 that's1059.84 okay.1059.84 We're1060.16 gonna1060.24 do1060.56 this1060.8 process1061.04 here1061.44 in1061.68 Lab1061.92 31062.24 and1063.36 then1063.52 pack1063.92 it1064.16 up1064.32 and1064.81 then1065.05 run1065.77 over1066.01 to1066.33 Lab1066.4 21066.64 to1066.88 continue1067.05 it,1067.53 you1067.92 know,1068.01 steps1068.33 four,1069.05 five,1069.21 and1069.21 six,1069.37 and1070.01 then1070.24 pack1070.33 it1070.49 up1070.64 and1070.81 then1070.88 bring1071.05 it1071.29 over1071.37 to1071.61 Lab1071.68 11072.09 for1072.4 the1072.73 last1072.88 three1073.21 or1073.53 whatever.1073.85 So1074.33 each1074.81 lab1075.45 has1075.68 its1075.92 own1076.16 distinct1076.49 processes1077.29 and1077.92 procedures.1078.88 1080.24 JAYNES1080.24 -1080.24 Yes.1080.24 1081.04 PARSONS1081.04 -1081.04 Okay.1081.04 And1085.28 so1085.6 why1087.28 the1087.6 move1087.76 or1088.16 the1088.32 expansion?1088.56 Just1089.52 more1089.84 work?1090.08 1091.84 JAYNES1091.84 -1091.84 Yep.1091.84 Exactly.1092.24 We1093.18 were1093.42 already1093.66 limited1094.14 in1094.55 our1095.11 original1095.35 lab1095.83 space,1096.07 and1096.31 we1096.47 hired1097.27 a1097.66 couple1097.75 more1097.99 scientists.1098.47 So1098.87 we1099.03 need1099.18 to1099.42 expand1099.59 and1099.99 get1100.07 more1100.31 space1101.35 for1101.75 biosafety1102.14 cabinets1102.87 and1103.75 other1103.9 things.1104.23 1105.87 PARSONS1105.87 -1105.87 Gotcha.1105.87 Okay.1106.59 Alright.1108.75 So,1119.15 in1119.15 which1119.39 lab1119.8 is1123.88 its1124.12 lentivirus1124.12 being1124.84 produced1126.28 in-house,1126.84 or1127.08 is1127.23 it1127.39 still1127.55 possible?1128.19 1129.23 JAYNES1129.23 -1129.23 Yeah.1129.23 Still,1129.55 it1129.8 might.1129.88 Haven't1130.19 done1130.84 that1131.08 yet.1131.32 1132.2 PARSONS1132.2 -1132.2 Okay.1132.2 Alright.1132.36 And1133.64 if1133.88 you1134.04 were,1134.2 which1135.8 lab1136.04 would1136.44 that1136.6 be1136.76 done1136.92 in?1137.16 1140.12 JAYNES1140.12 -1140.12 I1140.12 believe1140.36 that1140.92 would1141.16 be1141.32 Suite1142.76 120.1144.44 Okay.1146.11 1152.74 PARSONS1152.74 -1152.74 Alright.1152.74 Those1153.22 are1153.38 my1153.55 only1153.7 questions.1153.94 I'll1154.74 go1154.9 the1155.22 other1155.38 way1155.55 around.1155.7 Tim,1156.27 do1156.59 you1156.74 have1156.83 any1156.98 questions1157.22 for1157.55 Aaron?1157.7 1158.51 MAGUIRE1158.51 -1158.51 No.1158.51 I'm1158.74 good.1158.83 Thanks.1159.07 1161.66 PARSONS1161.66 -1161.66 Deb,1161.66 any1161.98 questions1162.22 for1162.54 Aaron?1162.7 We1166.54 didn't1166.78 hear1167.1 that.1167.34 You1167.58 definitely1167.82 unmuted,1168.22 but1168.62 it1168.86 didn't1168.94 come1169.26 through.1169.42 No1169.74 questions,1169.98 though.1170.38 Okay.1170.62 Ralph,1172.7 any1173.02 questions1173.26 for1173.66 Aaron?1173.9 1174.7 MELE1174.7 -1174.7 No1174.7 questions.1174.94 1176.88 PARSONS1176.88 -1176.88 Mia,1176.88 any1177.21 questions1177.37 for1177.68 Aaron?1177.92 1178.49 LIEBERMAN1178.49 -1178.49 Nope.1178.49 1180.09 PARSONS1180.09 -1180.09 Okay.1180.09 So,1180.73 Aaron,1180.97 thank1181.37 you1181.53 very1181.61 much1181.77 for1181.92 being1182.09 here1182.24 this1182.49 evening.1182.73 1183.61 JAAFAR1183.61 -1183.61 Thank1183.61 you.1183.85 1186.4 PARSONS1186.4 -1186.4 We,1186.4 you1186.97 know,1187.13 we1187.29 don't1187.45 like1187.68 I1188.11 don't1188.19 want1188.43 you1188.51 to1188.67 think1188.75 we're1188.99 wasting1189.23 your1189.55 time1189.71 or1189.87 anything1189.95 like1190.11 that.1190.27 But1190.43 when1190.59 the1191.07 expansion,1191.15 like,1191.63 of1191.87 this1191.95 size,1192.19 we1192.43 do1192.59 like1192.75 to1192.99 have1193.07 the1193.23 groups1193.39 come1193.71 in,1193.95 or1194.43 the1194.51 companies1195.15 come1195.55 in,1195.71 so1195.87 we1196.03 can1196.19 just1196.35 talk,1196.51 you1196.83 know,1196.91 through1197.23 a1197.47 couple1197.55 of1197.79 things.1197.95 This1199.87 does1200.11 not1200.27 mean1200.59 you1200.59 do1200.75 not1200.91 need1201.15 to1201.31 go1201.39 to1201.63 the1201.71 board1201.87 of1202.11 health1202.19 for1202.99 this.1203.15 But1205.44 we1205.68 do1205.85 appreciate1206.09 your1206.88 time,1207.05 and1207.44 just1207.68 so1207.85 we1208.01 can,1208.16 you1208.88 know,1209.13 still1209.68 get1210.33 a1210.57 sense1210.72 of1210.96 how1212.09 our1212.24 companies1212.48 are1212.88 doing1212.96 how1213.29 the1213.37 companies1213.53 are1213.85 doing1214.01 here1214.24 in1214.4 Watertown.1214.57 So,1215.13 best1216.16 of1216.4 luck1216.57 with1216.81 the1216.96 expansion,1217.13 with1218.48 your1218.72 research.1218.96 And1219.74 like1220.38 Zane,1220.62 you1220.94 are1221.1 free1221.26 to1221.42 go1221.5 if1221.74 you1221.9 wish.1222.06 1222.94 JAAFAR1222.94 -1222.94 Okay.1222.94 Thank1223.26 you1223.5 very1223.58 much.1223.74 1225.34 PARSONS1225.34 -1225.34 Have1225.34 a1225.46 good1225.58 evening.1225.82 Alright.1226.94 Right.1231.58 So1231.9 Dino.1232.22 Dino1232.7 is1233.18 up1233.34 next.1233.58 My1237.48 god.1237.72 I1237.88 need1238.04 another1238.28 monitor.1238.68 Okay.1241.09 So1241.48 this1241.64 is1241.8 our1241.96 prime1242.37 discussion1242.77 with1243.24 Luke.1243.48 So,1243.96 Luke,1244.13 I1244.44 do1244.61 see1244.77 you're1245.01 here.1245.24 1246.61 LUKE1246.61 AMIRAULT1246.61 -1246.61 DYNO1246.61 THERAPEAUTICS1246.61 -1246.61 Yes.1246.61 How's1246.85 it1247.09 going?1247.16 1248.17 PARSONS1248.17 -1248.17 I'm1248.17 well.1248.57 Thank1248.97 you.1249.13 Welcome1249.29 back.1249.69 Thank1250.01 you1250.17 for1250.41 you're1250.81 kinda1251.13 turning1251.45 into1251.77 a1252.01 regular1252.17 here.1252.65 1255.05 AMIRAULT1255.05 -1255.05 Yeah.1255.05 It's1255.05 good1255.37 to1255.61 be1255.69 here.1255.85 1256.57 PARSONS1256.57 -1256.57 Well,1256.57 and1256.81 we1256.97 do1257.21 appreciate1257.37 you1258.09 coming1258.73 back1259.05 because1259.21 we1259.53 do1259.69 the1260.09 whole1260.57 Prion1260.81 thing,1261.29 you1262.7 know,1262.87 it's1263.03 a1263.27 little1263.51 different.1263.74 So1268.7 what's1269.11 the1269.35 plan?1269.51 1270.07 AMIRAULT1270.07 -1270.07 Yeah.1270.07 So1270.22 I'm1270.38 gonna1270.46 go1270.7 ahead1270.79 and1271.03 share1271.18 my1271.42 screen.1271.59 1272.38 PARSONS1272.38 -1272.38 Oh,1272.38 great.1272.63 1273.03 AMIRAULT1273.03 -1273.03 We1273.03 have1273.27 two1273.59 slides.1273.83 I'm1274.14 actually1274.31 joined1274.63 tonight1274.94 by1275.35 my1276.52 colleague,1276.68 Jason,1277.16 who's1277.56 the1277.8 senior1278.04 scientist1278.36 and1278.76 the1279 PI1279.16 of1279.56 this1279.72 project.1281.64 So1282.36 he1282.6 can1282.68 help1282.92 give1284.04 some1284.28 more1284.44 context1284.6 from1285 the1285.16 scientific1285.32 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any1981.96 questions1982.36 for1982.84 either1983.08 Luke1983.32 or1983.64 Jason?1983.88 1985.08 MELE1985.08 -1985.08 No1985.08 questions.1985.4 1987.16 PARSONS1987.16 -1987.16 Deb,1987.16 any1987.56 questions1987.8 for1988.28 Luke1988.52 or1988.76 Jason?1988.92 1990.36 MCEWAN1990.36 -1990.36 No1990.36 questions,1990.68 but1991.24 can1991.64 you1991.8 hear1991.88 me1992.12 better?1992.2 1993.39 PARSONS1993.39 -1993.39 Perfectly,1993.39 actually.1995.08 Are1995.88 you1996.12 in1996.12 the1996.2 woods1996.28 now?1997.8 MCEWAN1997.8 -1997.8 Yep.1997.8 Switch1998.36 to1998.67 the1998.76 phone.1998.91 A1999.23 whole1999.32 new1999.47 place.1999.63 2004.28 PARSONS2004.28 -2004.28 Tim,2004.28 any2004.91 questions2005.15 for2005.56 either2006.28 Luke2006.6 or2006.99 Jason?2007.15 2007.89 MAGUIRE2007.89 -2007.89 Oh,2007.89 no.2008.05 I'm2008.13 good.2008.21 Thank2008.45 you.2008.77 We're2009.01 really2009.17 efficient.2009.41 Appreciate2009.73 it.2010.45 2012.21 PARSONS2012.21 -2012.21 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suffering.2951.55 2951.55 FOLEY2951.55 -2951.55 Did2951.55 you2951.8 have2951.88 a2952.2 fire?2952.36 2953.32 LIEBERMAN2953.32 -2953.32 No.2953.32 Flood.2953.32 2955.63 PARSONS2955.63 -2955.63 A2955.63 flood.2955.87 And,2956.35 like,2956.67 when2956.99 I2957.23 say2957.31 these2957.55 labs2957.71 were2958.03 newly2958.19 renovated,2958.59 they2959.07 were2959.15 reconstructed.2959.47 And2960.67 the2960.99 day2961.15 before2961.55 the2961.95 flood,2962.11 everything2962.99 was2963.47 certified.2963.63 Boston2965.07 fire,2965.55 we2966.03 got2966.19 all2966.43 the2966.59 permits.2966.75 The2967.15 air2967.31 was2967.55 balanced.2967.71 They2969.68 were2969.76 gonna2969.99 come2970.07 in2970.32 on2970.55 Monday2970.72 and2971.11 start2971.43 putting2973.11 stuff2973.51 in2973.84 there2973.99 to2974.32 do2974.72 their2974.95 thing,2975.51 and2975.84 the2976.16 pipe2976.39 froze2977.59 and2978.64 then2978.8 unfroze.2979.11 And2981.51 when2981.68 an2981.91 unfrozen2982.07 pipe2982.72 is2983.11 unfrozen,2983.28 and2984.07 it's2984.23 a,2984.47 oh,2984.84 I2985 don't2985.16 know,2985.24 a2985.96 four-inch2986.36 line2986.68 for2986.92 the2987.08 sprinkler2987.64 system,2988.2 Ralph.2988.6 There's2989.8 a2990.2 lot2990.28 of2990.44 water,2990.6 and2990.84 there's2991 not2991.16 an2991.4 automatic,2991.56 for2992.04 obvious2992.28 reasons,2992.68 an2994.2 automatic2994.44 shutoff2994.84 valve2995.24 on2995.64 the2996.04 sprinkler2996.36 system2996.76 because2997.16 you2997.4 don't2997.56 want2997.8 the2998.04 water2998.2 to2998.44 stop2998.6 if2998.84 there's2999.08 a2999.32 fire.2999.4 But3000.09 there3000.32 wasn't3000.41 a3000.89 fire.3001.05 3003.2 FOLEY3003.2 -3003.2 It3003.2 was,3003.36 like,3003.68 they3004.49 put3004.64 in3004.8 a3005.05 sprinkler3005.2 system3005.77 over3006.24 at3006.49 1243006.64 Watertown3009.13 Street3009.68 in3010.01 our3010.09 new3010.32 building,3010.49 and3010.97 our3011.13 well,3011.29 it's3011.53 an3011.68 old3011.77 building.3012.01 But3012.72 I3012.97 didn't3013.13 realize3013.53 those3014.6 pipes3014.84 are,3015.24 like,3015.4 this3015.64 big.3016.04 3016.84 PARSONS3016.84 -3016.84 Yeah.3016.84 3018.2 FOLEY3018.2 -3018.2 It3018.2 holds3018.44 a3018.76 lot3018.84 of3019.08 water.3019.24 3020.6 PARSONS3020.6 -3020.6 Oh,3020.6 yeah.3020.84 And3021 there's3021.16 plenty3021.32 behind3021.72 it,3021.96 too.3022.2 3022.84 FOLEY3022.84 -3022.84 I3022.84 had3023 no3023.32 idea.3023.64 3025.08 PARSONS3025.08 -3025.08 Yeah.3025.08 So3025.08 when3025.24 one3025.4 of3025.56 those3025.64 goes,3029.58 and3029.58 like3029.82 I3029.97 said,3030.14 by3030.38 design,3030.7 like,3031.02 there3031.26 are3031.49 some3031.58 lines3031.74 you3032.06 can3032.14 do,3032.3 like,3032.54 a3032.7 flow3032.86 meter3033.1 on3033.41 it,3033.49 and3034.22 it's3034.45 like,3034.61 oh,3034.78 this3034.93 water3035.1 is3035.34 flowing3035.49 too3035.89 fast3036.06 for3036.38 too3036.54 long.3036.7 Shut3037.02 it3037.26 off.3037.41 Not3038.38 on3038.61 a3038.86 fire3039.1 suppression3039.49 system.3040.06 It3040.61 is3040.78 the3040.93 opposite3041.1 of3041.66 what3041.82 you3041.82 want.3042.52 So3042.6 it3042.92 just3043.08 kept3043.24 going3043.48 and3043.72 going;3043.8 it3044.04 took3044.2 quite3044.36 a3044.52 while3044.68 for3044.84 someone3045 to3045.32 realize,3045.48 because3045.8 it3046.04 was3046.12 not3046.28 occupied3046.6 yet,3049.4 that3050.52 there3050.68 were3050.92 a3051.16 couple3051.32 of3051.56 feet3051.56 of3051.8 water3051.96 in3052.2 there.3052.36 But3057.64 I3057.64 didn't3057.8 have3058.2 to3058.36 go,3058.44 but3058.68 Mia3059.24 did.3059.32 3060.2 LIEBERMAN3060.2 -3060.2 Well,3060.2 I3060.44 haven't3060.61 been3060.92 in3061.16 there,3061.24 but3061.64 my3061.96 colleagues3062.13 have3062.61 been.3064.2 I've3064.36 been3064.44 having3064.61 the3064.92 problem3065.09 solved3065.41 around3065.96 the3066.2 building3066.36 closures.3066.84 3068.51 PARSONS3068.51 -3068.51 Well,3068.51 so3068.67 then3068.72 Boston3068.78 Fire3068.83 came3069.55 in3069.79 and3069.95 said,3070.03 alright.3070.27 These3070.51 two3070.67 buildings,3070.91 which3071.23 happen3071.47 to3071.71 be3071.87 33%3075.95 of3076.99 the3077.15 quad.3077.71 And3078.35 I3078.59 know3078.67 the3078.91 quad3079.07 sounds3079.31 like3079.55 it3079.71 should3079.79 be3079.95 four,3080.19 but3080.43 it's3080.59 not.3080.75 So3082.3 in3082.61 that3082.78 much3082.93 of3083.17 and3083.41 it3083.57 wasn't3083.65 just3083.97 the3084.21 floors3084.3 that3084.61 were3084.86 affected.3085.01 So3086.21 it3086.61 was3086.78 the3087.09 medical3087.26 school3087.57 that3088.13 got3088.13 punched3089.09 in3089.73 the3090.13 gut3090.38 big3092.78 time,3093.01 which3093.59 I'm3093.75 not3093.91 blaming3093.99 Boston3094.47 Fire3094.79 for3095.03 shutting3095.11 the3095.35 building3095.51 down.3095.75 I3095.75 mean,3095.91 it3096.07 was3096.23 not3096.63 good.3096.79 Alright.3099.51 So3101.75 future3102.63 meetings.3103.03 Next3106.4 up3106.72 would3106.96 be3107.2 March3107.44 5.3108.26 Does3110.09 anyone3110.32 have3110.8 any3111.2 scheduling3111.44 conflicts3112.09 with3112.57 March3112.8 5?3113.21 No?3116.4 Tim,3119.23 would3119.79 you3120.03 be3120.11 able3120.19 to3120.43 make3120.51 the3121.07 March3121.23 5?3121.68 3122.59 MAGUIRE3122.59 -3122.59 You3122.59 bet.3122.75 Works3122.99 perfectly.3123.23 Yep.3123.63 3124.43 PARSONS3124.43 -3124.43 Okay.3124.43 Ralph,3125.15 I3125.47 see3125.55 you3125.79 shaking3125.87 your3126.19 head.3126.43 So3126.75 alright.3127.23 We'll3127.55 stick3127.71 to3127.95 our3128.19 first3128.43 Thursday3128.75 of3129.23 the3129.39 month,3129.55 cadence.3130.59 And3133.82 I3135.26 can't3135.49 end3136.38 this3136.78 meeting.3137.01 I3138.93 can't3139.09 do3139.26 it,3139.41 Maureen.3139.66 You3140.14 and3140.45 I3140.61 were3140.7 both3140.93 there.3141.18 3142.78 FOLEY3142.78 -3142.78 We3142.78 were.3143.01 3144.14 LIEBERMAN3144.14 -3144.14 I3144.14 motion3144.38 to3144.86 adjourn3145.09 the3145.49 meeting.3145.57 3147.02 PARSONS3147.02 -3147.02 I3147.02 can't3147.18 even3147.34 second.3147.66 3148.54 FOLEY3148.54 -3148.54 You3148.54 again,3148.54 Mia.3148.54 Ralph.3150.54 3151.1 MELE3151.1 -3151.1 Second.3151.1 3155.1 FOLEY3155.1 -3155.1 Thank3155.1 you,3155.42 Ralph.3155.74 Okay.3159.26 Roll3159.82 call.3160.14 Brad3162.39 Parsons.3162.8

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3169.91 SPEAKER53169.91 -3169.91 Yes.3169.91

3172.16 SPEAKER73172.16 -3172.16 Deb3172.16 McGowan.3172.47

3173.36 SPEAKER43173.36 -3173.36 Yes.3173.36

3174.48 SPEAKER73174.48 -3174.48 Tim3174.48 McGuire?3175.12

3176 SPEAKER83176 -3176 Yes.3176

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