Watertown Biosafety Committee
Thursday September 5, 2024
The order of items in transcripts appear in the chronological order in which they were taken up. Some Agenda items may have been skipped.
BRADFORD14.82 PARSONS14.82 -14.82 BIOSAFETY14.82 COMMITTEE14.82 CHAIR14.82 -14.82 Alright.14.82 We're15.29 gonna15.46 call15.7 this15.86 meeting16.1 to16.34 order.16.89 Calling17.54 the17.54 September17.94 202421.54 Watertown24.6 Biosafety25 Committee25.64 meeting26.2 to26.52 order.26.76 Thank27 you27.24 everyone27.48 for27.8 being27.96 here28.2 this28.44 evening.28.6 Following30.28 the30.6 agenda,30.84 the31.8 second32.28 item33.08 is33.56 the33.8 acceptance33.88 of34.52 minutes35 as35.4 approved35.8 by36.36 Maureen.36.84 So38.34 does38.66 anyone38.83 from39.15 the39.38 biosafety39.55 committee40.1 have40.51 any40.66 suggestions,40.98 or42.19 corrections42.51 or43.3 edits43.63 for44.27 the44.42 minutes?44.59 Okay49.7 seeing50.02 none,50.02 we'll50.27 just50.42 do50.59 a50.74 quick50.91 vote.51.15 All53.05 those53.29 in53.37 favor53.61 of53.93 accepting54.17 the54.57 minutes54.73 as55.13 submitted56.49 by56.89 Maureen,57.05 please57.45 either57.77 raise58.09 your58.25 hand58.41 or58.57 say58.73 aye.59.05 Okay.60.41 For60.73 those60.97 who61.21 don't61.85 have62.17 cameras,62.33 everyone62.73 raised63.13 their63.37 hands.63.61 So63.93 thank64.17 you,64.33 Maureen,64.57 again,64.97 for66.17 your66.33 great66.57 work.66.81 We67.05 really67.29 appreciate67.61 it.68.01 And68.94 the69.19 minutes69.34 are69.83 accepted.70.06
SHOW NON-ESSENTIAL DIALOGUE
85.21 PARSONS85.21 -85.21 Okay.85.21 At85.61 this85.85 point86.01 of86.73 the86.73 agenda86.97 is87.29 the87.53 time87.69 for87.93 public88.09 comment.88.49 So88.81 I88.97 do89.13 wanna89.21 make89.53 it89.69 clear89.85 that90.09 when91.37 it91.61 comes91.77 time92.09 for92.57 the92.89 review93.05 of93.45 the93.53 permit93.61 applications94.09 and94.65 the94.81 amendments,94.97 questions95.53 are95.93 reserved96.17 for97.03 the97.2 members97.28 of97.52 the97.67 committee.97.92 So98.64 the99.12 public99.28 comment99.76 time100.48 is100.88 now102 and102.56 the102.8 opportunity102.95 for103.52 anyone103.67 from104 the104.16 public104.23 to104.95 make106.16 any106.4 comments106.8 to107.36 the107.67 committee107.76 or108.31 the108.56 city.108.72 But109.52 we109.67 also109.84 like110.16 to110.4 accept111.76 generic113.07 or113.31 holistic113.79 questions114.27 about114.67 biosafety115.07 in115.71 general.115.87 So117.23 if117.55 there's118.35 any118.75 public118.99 comment,119.31 please,119.71 raise120.59 your120.83 hand121.07 using122.43 the122.75 raise123.63 hand123.95 function,124.19 and124.83 then125.07 state125.39 your125.71 name125.95 and126.19 your126.35 address.126.59 Okay.135.4 So135.79 seeing136.28 no136.59 public137.31 comment,137.72 we138.12 will138.28 now138.51 go138.75 on139 to139.24 number139.4 4,139.72 the140.12 permit140.28 application140.75 for141.4 Jana142.2 Care.143.72 So143.72 if,144.12 excuse145.72 me,146.28 sorry.147.96 I147.96 invite148.2 a148.44 representative148.68 from149.56 Jana149.8 Care150.52 to150.52 give150.76 us150.92 a151.24 brief151.96 introduction.152.36 I'm154.12 assuming154.44 that's154.92 gonna155.08 be155.32 Richard155.48 Williams.155.8 If158 you158.08 have158.25 a158.49 deck,158.56 great.158.88 You159.13 should159.28 be159.44 able159.53 to159.69 share159.84 your160.08 screen.160.25 If160.56 you160.72 don't160.81 have161.04 a161.21 deck,161.36 that's161.6 okay.161.84 But163.04 a163.28 brief163.36 introduction163.92 to164.41 your164.49 company,164.72 and165.21 then165.36 we'll165.6 take165.84 it166 from166.16 there.166.32
SHOW NON-ESSENTIAL DIALOGUE
194.58 RICHARD194.58 WILLIAMS194.58 -194.58 JANA194.58 CARE194.58 -194.58 Okay.194.58 So194.91 I'll195.38 go195.63 ahead.195.71 My196.1 name196.26 is196.43 Richard197.14 Williams.197.54 I198.1 am198.26 the198.43 chief198.58 scientific198.99 officer199.63 of200.26 Jana202.29 Care.202.93 Jana202.93 Care202.93 is202.93 a203.17 small203.33 medical203.89 device204.37 company204.85 that206.05 was206.45 founded206.61 in206.93 the207.09 Boston207.25 area207.65 a208.05 few208.13 years208.37 ago,208.61 and209.33 we're209.57 in209.81 the209.97 process210.05 of210.53 moving210.85 into211.25 a211.49 new211.65 facility212.05 in213.25 Watertown213.49 at214.45 313215.01 Pleasant215.97 Street.216.61 So218.41 Jana218.72 Care220.16 develops220.16 and220.81 manufactures221.04 home222.64 blood223.13 tests223.36 for224.49 people224.72 with225.04 chronic225.13 diseases.225.44 It's226.72 a226.97 little227.04 bit227.28 like227.6 the229.21 kind229.44 of229.69 test230.55 that230.79 someone231.03 with231.35 diabetes231.59 would232.23 use232.47 to232.71 check232.87 their233.03 blood233.27 sugar.233.43 We're234.55 developing234.87 tests235.83 like236.15 that236.39 for236.95 other237.91 phonic238.47 diseases238.87 such239.59 as240.07 kidney240.47 failure240.95 and242.63 heart243.67 failure.243.91 So246.35 the246.67 way246.91 our247.16 system247.31 works247.72 is248.11 that248.28 we248.59 have248.75 disposable249.16 test249.96 strips250.28 and250.59 a250.75 reader250.91 device251.24 and251.79 an252.35 app252.59 on252.91 the253 phone.254.28
254.59 And254.59 so254.59 the254.83 patient255.72 pricks256.12 their256.44 finger256.68 with257.07 a257.31 disposable257.79 lancet,258.81 gets259.45 a259.69 little259.85 drop260.17 of260.41 blood,260.57 and261.37 puts261.53 it261.77 onto261.85 the262.09 test262.25 strip.262.57 So264.01 the264.25 reason264.33 we're264.65 before264.89 you265.29 this265.69 evening265.93 is266.49 because,266.89 although268.09 we268.65 do268.89 not269.05 do269.37 any269.61 work269.93 with270.57 DNA272.04 or272.52 any272.84 recombinant273.16 or273.64 synthetic273.88 nucleic274.37 acids,274.84 and275.49 we275.64 do275.81 not276.04 do276.28 any276.6 work276.84 with277.32 microorganisms278.93 or280.2 known281 infectious281.49 disease282.13 agents,282.52 we283.49 do283.72 need284.37 to284.69 use284.93 human285.4 blood285.88 to286.83 develop287.87 and288.35 test288.59 our288.99 products.289.79 And291.39 because291.87 we're292.19 working292.51 with292.91 human293.15 blood,293.55 we293.95 need294.19 to294.35 handle294.59 that294.99 safely296.03 and296.59 in296.83 accordance296.99 with297.47 OSHA298.83 and299.39 CDC299.71 regulations.300.27 And301.28 so301.36 that301.68 involves301.92 the302.4 use302.48 of302.72 a305.12 facility305.36 that306.07 complies306.4 with306.88 the307.04 requirements307.19 of307.75 BSL308.72 2,309.19 biosafety309.44 level310.07 2.310.4 So312.63 I315.06 think315.14 that's315.38 a315.62 general315.7 overview,316.18 and316.58 I316.74 would317.3 be317.54 glad317.7 to317.94 answer318.1 any318.5 questions318.74 about319.22 our320.5 plans321.46 or321.86 anything322.02 else.322.42
SHOW NON-ESSENTIAL DIALOGUE
334.9 MIA334.9 LIEBERMAN334.9 -334.9 BIOSAFETY334.9 COMMITTEE334.9 MEMBER334.9 -334.9 Yeah.334.9 My335.15 only335.31 question335.55 was335.87 just336.02 the336.26 source336.43 of336.75 the336.9 blood.337.06 Is337.38 the337.55 blood337.71 being338.02 collected338.43 at339.15 the339.31 facility339.46 or340.02 are340.26 you340.35 sourcing340.59 blood341.15 from341.46 another342.69 source?343.33
344.61 WILLIAMS344.61 -344.61 We344.61 consider345.65 three346.37 possibilities.347.09 One349.65 is350.13 that350.69 we351.41 do352.53 plan352.85 to353.41 obtain354.05 blood355.54 samples355.79 from356.58 local358.19 companies.358.58 There's358.99 one359.14 in359.38 Watertown359.46 and360.02 other360.19 companies360.5 that361.14 obtain362.66 blood363.14 from363.54 healthy364.99 volunteers366.66 for366.99 research367.23 purposes.367.94 So369.54 that370.02 blood370.34 would370.66 be370.9 kind373.3 of373.54 drawn373.78 like374.1 it374.34 would374.42 in374.66 a374.82 blood376.02 test376.26 at376.5 the376.58 doctor376.74 where377.06 you377.3 have377.38 a377.54 tube377.62 of377.94 blood,378.02 and378.98 so379.22 those379.46 tubes379.7 would380.1 be380.26 provided380.66 to381.14 us.381.3 Possibility383.31 2384.1 is384.75 that,385.06 our386.75 own387.06 employees387.38 would387.94 volunteer388.5 to389.22 prick389.46 their389.79 finger390.02 and391.78 use392.19 the392.5 device.392.75 And394.58 the394.82 third394.99 possibility395.22 would396.26 be396.58 participants398.34 in398.9 a399.06 clinical399.22 study.399.62 In401.06 that401.22 case,401.46 these401.86 would402.1 be402.26 participants403.86 who404.58 would405.22 volunteer405.54 for406.02 the406.26 study,406.42 would407.46 provide407.86 informed408.34 consent,408.82 and409.7 the409.94 study410.1 would410.42 be410.58 conducted410.74 under411.46 the411.94 supervision412.1 of412.74 an412.98 institutional413.92 review414.71 board.415.12 So415.28 that's415.44 an416 organization416.24 that417.04 is417.68 responsible418 for418.56 overseeing419.28 the419.75 ethics420.31 of420.71 human421.51 subject421.92 research.422.31 So424.63 I425.6 think425.81 I425.97 listed426.13 those426.45 in426.69 order426.77 of427.01 likelihood.427.09 Most427.57 of427.89 it428.05 will428.29 be428.45 from428.77 option430.05 1.430.37
431.89 LIEBERMAN431.89 -431.89 And431.89 so432.05 is432.29 it432.53 being432.69 commercially433.01 couriered433.73 to435.09 the435.49 lab,435.65 or436.13 how436.37 are436.61 you436.69 pursuing437.57 it?437.57
437.57 WILLIAMS437.57 -437.57 That's438.61 correct.438.85 So439.17 it439.33 would439.49 be439.65 delivered440 to440.24 the440.35 lab440.48 either440.95 by442.63 a442.79 commercial442.88 courier443.35 or443.92 by444.15 the444.31 courier444.48 of445.04 the445.27 company445.44 that446 collects447.19 the447.6 blood.447.75
448.63 LIEBERMAN448.63 -448.63 Okay.448.63 Perfect.449.04 For450.24 the,450.48 if451.68 employees451.92 choose452.79 to453.44 offer454.15 their454.56 blood455.55 for455.79 testing,456.03 will456.99 there457.23 be457.39 an457.55 IRB457.79 involved458.27 for458.67 that?458.83
460.11 WILLIAMS460.11 -460.11 There460.11 would460.35 not460.51 be460.75 an460.91 IRB461.23 but461.79 there461.95 would462.19 be462.35 informed462.59 consent.463.15 So464.91 we466.11 would466.35 be467.23 very467.39 clear467.71 that467.95 it's468.11 not468.35 a468.51 condition468.59 of468.99 employment469.15 that469.79 you470.03 participate470.19 and471.88 that472.04 you472.28 can472.44 stop473.31 participating473.63 at474.12 any474.28 time.475.8 And477.24 no477.24 adverse477.48 employment478.04 consequences478.6 would479.31 be479.56 related479.8 to480.28 not480.6 participating.481.88 But482.19 it's482.19 not482.6 required485.65 to486.05 have486.13 an486.29 IRB,486.53 and486.85 so487.01 we487.25 would487.41 not488.05 be488.21 doing488.37 that.488.53
490.21 LIEBERMAN490.21 -490.21 Okay.490.21 Thank490.53 you.490.77 Those491.01 are491.17 all491.33 my491.49 questions.491.65
SHOW NON-ESSENTIAL DIALOGUE
502.88 RALPH502.88 MELE502.88 -502.88 BIOSAFETY503.51 COMMITTEE504.07 MEMBER504.07 -504.07 Yep,504.07 just504.07 one.504.07 The504.07 space504.31 looks504.63 like504.8 it's504.96 gonna505.12 be505.36 shared505.51 space.505.75 Who506.63 is506.8 it506.96 being507.36 shared507.75 with?508.31
509.8 WILLIAMS509.8 -509.8 Yes.509.8 So510.04 the510.68 current511.96 plan512.36 is512.92 that513.16 there513.32 would513.48 be513.64 an513.8 incubator513.96 space514.6 that515.56 would515.72 be516.84 organized518.68 by519.24 the519.4 landlord519.64 alongside520.92 another522.82 company523.13 that523.53 would523.7 help523.86 with524.1 the524.25 management524.41 of524.82 that524.98 incubator.525.21 At526.82 present,527.05 we527.46 are527.62 the527.86 only528.01 tenants528.25 and528.89 we529.38 have529.7 a531.05 direct531.29 lease531.77 from532.1 our532.25 landlord532.5 for532.89 exclusive533.13 use533.7 of534.01 our534.5 area.535.05 And535.77 so536.1 we538.36 do538.6 have538.76 a539 room539.16 in539.4 that539.56 space539.8 that540.12 is540.6 exclusively540.92 ours.541.64
543.56 MELE543.56 -543.56 Okay.543.56 Thank543.96 you.544.2
549.77 PARSONS549.77 -549.77 Okay.549.77 I553.13 only553.29 have553.53 one554.58 question555.86 and555.86 it's555.86 about555.86 the555.86 community556.17 representative556.89 on557.62 your557.77 IBC,558.1 Robert558.65 Shivers.559.29 It561.13 states561.38 that561.7 he561.86 works562.01 in562.34 Bedford562.5 but563.6 does564 he564.24 live564.4 in564.64 Watertown?564.8
566.96 WILLIAMS566.96 -566.96 Yes.566.96 He567.2 does.567.36
567.92 PARSONS567.92 -567.92 Okay.567.92 So568.96 for569.2 future569.44 reference,569.76 on572.24 an572.4 application572.56 like573.2 this573.36 to573.6 have573.76 how574.72 they're574.88 affiliated575.12 with575.52 Watertown575.76 is576.32 really577.13 helpful577.38 because578.65 that's578.89 the579.21 part579.29 that579.53 makes579.7 them579.93 qualified,580.89 if581.05 they581.21 work581.45 or581.77 live582.01 in582.25 Watertown,582.58 or584.17 the584.33 immediate584.58 vicinity.585.05
586.01 WILLIAMS586.01 -586.01 That586.41 makes586.58 sense.586.74 So586.98 we'll587.13 make587.53 sure587.7 we587.86 clarify588.01 that.588.5
588.89 PARSONS588.89 -588.89 Oh,588.89 that's588.97 fine.589.21 No.589.45 You589.69 don't589.77 need590.25 to590.41 change590.49 anything.590.73 I591.77 just591.93 wanted592.17 to592.29 make592.41 sure.592.57 And592.81 then592.97 also,593.13 we593.45 have593.61 some593.77 other595.21 people595.45 on595.61 this595.77 call596.01 that596.25 are596.41 consultants596.57 that597.13 also597.29 work597.61 with597.77 other597.93 clients.598.17 So598.49 just598.65 so598.89 that598.97 they599.13 know,599.29 yeah,600.65 the600.97 place601.21 of601.53 employment601.69 is602.25 only602.41 important602.73 if603.13 they're603.29 working603.53 in603.85 Watertown,604.01 which605.17 qualifies606.38 them606.93 to607.17 be607.25 a607.98 member608.13 of608.46 the608.54 IBC.608.77
609.98 WILLIAMS609.98 -609.98 That609.98 makes610.13 sense.610.38 Thank610.7 you.610.86
611.58 PARSONS611.58 -611.58 Alright.611.58 So,612.29 yeah,613.1 Tim's613.34 not613.74 here.613.98 He614.29 didn't614.46 send614.77 me614.93 anything.615.1 So,615.74 would617.34 someone617.5 like617.89 to618.05 make618.22 a618.7 motion618.93 to619.82 approve621.31 Jana622.35 Care's622.75 application623.31 as623.95 submitted?624.19
627.55 LIEBERMAN627.55 -627.55 I627.55 move627.87 to628.19 approve628.35 Jana628.83 Care's629.31 permit630.27 application630.91 as631.71 submitted631.87 or633.2 send633.45 recommendations634.17 for634.88 approval635.04 to635.37 the635.52 board635.61 of635.85 health.635.92 I636.4 think637.04 that's637.04 technically637.04 how637.04 we're637.04 not637.13 supposed637.28 to637.52 phrase637.61 it.637.85
SHOW NON-ESSENTIAL DIALOGUE
DEBORAH643.37 MCEWAN643.37 -643.37 BIOSAFETY643.37 COMMITTEE643.37 MEMBER643.37 -643.37 Second.643.37
643.37
SHOW NON-ESSENTIAL DIALOGUE
PARSONS661.07 -661.07 Okay.661.07 Great.661.39 So,661.71 Richard,661.95 the663.88 next663.95 step664.27 for664.91 you665.15 is665.79 to666.2 present666.51 to666.83 the667 board667.07 of667.32 health.667.48 It's667.71 gonna667.95 be668.2 very,668.36 very668.67 similar668.91 to669.32 this.669.39 So669.63 we671.48 don't671.63 approve671.88 permanent672.6 applications,673.63 we673.79 just,673.79 you674.12 know,674.27 move674.51 it674.67 along674.83 to675.15 the675.24 board675.39 of675.63 health.675.71 So,676.23 Maureen,677.35 do677.91 we678.15 have678.31 a680.63 date680.79 for681.11 that681.35 meeting?681.59
692.96 LIEBERMAN692.96 -692.96 Should692.96 be693.2 the693.43 18th,694.08 right?694.63
694.63 MAUREEN694.63 FOLEY694.63 -694.63 CITY694.63 OF694.63 WATERTOWN694.63 -694.63 18th.694.63 Yes.695.12
697.43 PARSONS697.43 -697.43 Okay.697.43 So,697.75 Richard,698 do698.32 you698.48 anticipate698.55 you699.2 or699.36 someone699.6 from699.92 your700.08 company700.24 being701.12 able701.27 to701.51 attend701.75 that702 meeting?702.24
703.04 WILLIAMS703.04 -703.04 Yes.703.04 I703.28 plan703.44 to703.76 attend703.92 that704.08 meeting.704.24
704.8 PARSONS704.8 -704.8 Okay.704.8 Great.705.12 Yeah.705.6 So705.84 they'll706 probably707.36 ask707.68 you707.84 just707.92 a708.08 couple708.16 of708.4 questions708.48 very708.88 similar709.12 to709.44 this,709.6 and710.32 off710.64 you710.8 go.710.88
712.24 WILLIAMS712.24 -712.24 Thank712.64 you,712.88 and713.04 we713.68 appreciate713.84 the715.68 committee's715.75 time716.48 this716.8 evening716.96 and717.36 look717.92 forward718.15 to718.39 being718.56 part718.96 of719.2 the719.27 community.719.43
720.15 PARSONS720.15 -720.15 Great.720.15 Thank720.39 you720.63 very720.72 much,720.88 Richard,721.12 and721.27 best721.51 of721.68 luck721.75 with722 your722.15 research.722.32
723.12 WILLIAMS723.12 -723.12 Thank723.12 you.723.36 Good723.92 night.724.15
SHOW NON-ESSENTIAL DIALOGUE
741.54 PARSONS741.54 -741.54 Okay.741.54 So741.93 up742.34 next,742.58 we743.05 have743.3 an743.93 amendment744.25 application744.82 for745.46 Cultivarum.750.18 So750.18 I750.74 was750.89 a751.05 little751.22 confused751.54 by752.18 this752.34 so752.58 I'm752.74 not752.82 even753.05 gonna753.3 preface753.7 it754.58 at754.82 all,754.89 but755.72 something756.04 to756.36 do756.52 with756.68 prescreening.756.84 So,758.2 I759.56 invite759.8 someone760.2 from760.6 Cultivarium762.28 to763.16 speak.764.28 If764.92 you765.08 have765.24 a765.4 deck,765.48 that's765.8 fine766.28 if766.44 you766.44 don't,766.52 that's766.84 all767.08 also767.32 fine.767.72 But768.84 explain769.46 to769.78 us,770.06 the770.5 need770.66 for770.83 the770.99 amendment.771.63
SHOW NON-ESSENTIAL DIALOGUE
819.67 ZAIRA819.67 MOLDES819.67 -819.67 CULTIVARIUM819.67 -819.67 Okay.819.67 So820.07 I'm820.31 going820.79 to821.03 start.821.11 So,821.51 well,823.88 thank824.2 you824.43 very824.6 much824.75 for825.08 having826.2 us826.51 today.826.75 I'm827.55 going827.8 to828.04 skip829.24 the829.48 biosafety829.63 at830.68 Cultivarium830.92 and830.92 bio831.08 waste831.32 management831.55 because832.12 we832.68 don't832.84 have833.15 any835.63 changes.835.88 But835.88 there835.88 is836.12 a836.43 project836.75 registration837.24 amendment837.88 that838.27 we838.7 want838.94 to839.22 present839.5 to839.98 the840.14 committee840.38 for841.9 approval842.14 that843.18 involves843.42 expanding844.46 recombinant845.42 DNA846.06 sources846.46 to847.42 risk847.82 group848.06 3,848.38 and849.58 a849.82 new849.98 review850.3 procedure.850.7 And852.85 we853.08 can853.25 review853.4 the853.88 bio854.2 waste854.45 at856.04 any856.28 time856.52 if856.85 you857 want857.08 to.857.33 But858.2 I858.45 want858.52 to858.76 focus859 on859.4 this859.73 because860.04 this860.37 is860.61 the860.68 big860.85 change861.08 that861.57 we861.96 are862.13 pursuing.863.08 It's863.8 the,864.04 for865.26 this865.5 project,865.82 exploration866.7 of867.18 microbial867.34 utility867.9 in868.38 laboratory868.7 culture,870.14 DNA870.7 delivery,871.18 and871.82 genetic872.06 tools.872.54 What875.02 we875.18 do875.42 is,875.66 we876.06 have877.11 a877.23 small877.35 sample877.75 cultures878.14 of878.71 understudied879.02 microbes,879.75 and881.02 we881.18 grow881.59 them881.83 to882.47 explore882.71 their883.02 ability883.26 to883.75 be883.83 cultured884.07 in884.63 lab,884.87 and885.26 also885.59 assess886.63 the886.95 success887.18 of887.59 DNA887.75 delivery.888.23 And889.35 we889.59 generate889.83 libraries890.47 of890.95 genetic891.02 parts891.59 to893.24 be893.4 delivered893.64 to894.12 these894.36 microorganisms894.68 and895.64 screen895.88 for896.12 functionality.896.36
898.04 The898.04 amendment898.28 that898.68 we898.84 are899 pursuing899.16 is900.04 to900.28 broaden900.44 the900.84 scope901 of901.48 work901.8 to902.28 include902.44 additional903.16 organisms903.72 with904.76 group905 1905.88 organisms,906.28 adding908.15 recombinant908.55 DNA909.2 from910 risk910.32 group910.55 3910.8 organisms,911.2 including912.32 nonhazardous913.04 sequences913.84 that914.48 are914.72 sourced914.88 from915.36 these915.75 organisms,916.08 and917.92 a918.32 new918.48 review918.88 procedure919.67 for920.72 screening920.96 hazardous921.43 sequence.926.93 I'm926.93 showing927.25 in927.65 here927.81 the928.05 list928.29 of928.61 additional928.77 organisms929.33 that929.89 we930.37 want930.69 to931.01 include931.25 in931.73 our931.89 list933.73 of934.05 agents.934.37 As935.73 you935.89 can936.05 see,936.21 all936.45 of936.61 them936.69 are936.93 risk938.45 group938.6 1,938.6 a938.6 few938.6 of938.83 them939 have939.31 been939.55 linked939.63 to939.95 disease940.12 in940.51 humans,940.75 but941.24 it's941.48 always941.79 in942.19 immunocompromised,942.6 humans.944.75 And945.71 they946.03 are946.27 still946.43 linked946.83 and947.24 categorized948.6 as949.31 risk949.55 group949.79 1.950.03 But950.75 in951 any951.15 case,951.48 we're952.12 going952.43 to952.75 treat953 them953.31 as953.78 biosafety954.1 level954.66 2955.06 containment955.3 in956.02 our956.26 lab,956.74 we're956.98 going956.98 to957.14 handle957.3 them957.62 in958.1 biosafety958.34 level958.9 2959.22 containment.959.46
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1664.16 MCEWAN1664.16 -1664.16 Risk1665.41 is1665.98 still,1666.3
1668.3 MOLDES1669.34 -1669.34 Yes.1669.34
1669.34 MCEWAN1669.34 -1669.34 And1669.34 then1669.49 I1669.98 guess1670.13 the1670.38 other1670.46 part1670.7 is,1671.02 so1671.82 as1672.3 these1673.63 detection1674.03 methods1674.75 improve,1675.39 is1676.59 it1676.83 generally,1677.87 I1679.79 guess,1679.95 going1680.27 to1680.51 be1680.67 standard1680.91 practice,1681.23 do1681.63 you1681.71 think,1681.79 to1682.03 keep1682.19 rescreening1682.51 them,1683.23 or1684.43 is1685.39 sort1685.63 of1685.79 a1685.95 onetime1686.27 screening1687.07 sufficient?1688.3 I1688.7 mean,1688.86 of1689.1 your1689.74 set,1690.06 you1690.46 know,1690.62 I'm1691.1 sure1691.17 you've1691.34 identified,1691.58 but1692.3 for1692.62 other1692.78 promoters1693.1 that1693.65 you1693.89 create.1694.13
1695.74 MOLDES1695.74 -1695.74 So1695.74 the1696.62 promoters1697.49 that1698.13 we1698.38 are1698.62 going1698.86 to1699.26 use,1699.89 every1701.25 single1701.49 sequence1702.13 is1702.77 going1702.93 to1703.17 be1703.33 now1707.01 run1707.01 through1707.17 the1707.41 program1708.05 so1708.53 that1708.77 we1708.93 can1709.09 identify1709.49 early1710.61 on1710.85 if1711.41 these1711.65 sequences1714.69 are1714.69 sourced1714.93 from1715.33 what1716.89 type1717.06 of1717.38 organism.1718.02
1718.73 MCEWAN1718.73 -1718.73 Yeah.1718.73
1719.21 MOLDES1719.21 -1719.21 Yeah.1719.21
1724.1 MCEWAN1724.49 -1724.49 And1724.49 so,1724.49 did1724.49 you1724.73 inform1724.89 Twist1725.45 Biosciences1726.17 that1727.21 they1727.45 should1729.54 have1729.62 flagged1729.94 this1730.26 and1730.82 they1730.98 missed1731.22 it,1731.46 or1731.7 is1731.94 that1732.18 still,1733.22 like,1733.54 are1733.62 they1733.86 aware?1733.94
1735.38 MOLDES1735.38 -1735.38 We1735.38 have1735.78 not1736.18 communicated1737.06 anything1737.78 to1738.42 Twist.1738.66 We1739.78 just1740.02 wanted1740.34 to1740.66 stop1741.46 distribution1741.78 of1742.5 the1742.74 kit.1742.9 We1745.19 have1745.36 not1745.52 communicated1746.55 that.1746.63
1746.8 MCEWAN1746.8 -1746.8 I'm1746.8 not1746.95 saying1747.04 that1747.28 that's1747.36 on1747.6 your1747.76 company.1747.84 Just1748.23 in1748.39 terms1748.63 of,1749.67 you1749.84 know,1749.84 thinking1750.15 the1750.63 whole1750.88 picture,1751.19 these1752.55 should1752.8 be1752.95 identified1753.19 before1753.76 any1754.15 DNA1755.12 sequences1755.52 are1755.99 made.1756.15
1757.19 MOLDES1757.19 -1757.19 Yeah.1757.19 Yeah.1757.67 No,1759.48 you're1760.28 right1760.28 but1760.28 we1760.28 can1760.52 only1760.68 control1761.08 what1762.6 we1762.76 do.1762.92 And1764.44 because1764.68 of1765 that,1765.16 we1765.88 decided1766.28 to1766.76 implement1766.92 this1767.96 new1768.28 assessment1769.4 for1770.36 the1770.6 sequences,1770.76 and1771.4 every1772.39 single1772.63 sequence1773.12 is1773.52 going1773.67 to1773.99 be1774.63 analyzed1774.88 because1776.23 we1776.47 don't1776.71 want1776.95 this1777.12 to1777.36 happen1778.08 again.1778.39
1779.28 MCEWAN1779.28 -1779.28 Yeah.1779.28 I1779.52 think1779.6 this1780.8 is1780.95 wonderful,1781.84 and,1782.47 you1782.88 know,1782.95 thank1783.43 you1783.67 for1783.84 laying1783.99 it1784.23 out1784.32 and1784.55 being1784.8 proactive.1785.04 I1787.09 don't1787.25 have1787.81 any1788.05 other1788.85 questions.1789.09
SHOW NON-ESSENTIAL DIALOGUE
1794.37 LIEBERMAN1794.37 -1794.37 Yeah.1794.37 I1794.61 have1795.33 some1795.49 questions.1795.73 So1796.69 I1797.65 guess1797.81 my1798.21 question1798.37 is,1799.09 you1800.13 got1800.3 these1800.54 sequences1800.62 from1801.1 a1801.41 paper,1801.89 so1802.06 if1802.06 you'd1802.13 thrown1802.45 them1802.7 in1802.86 the1803.02 blast,1803.26 would1803.82 they1804.06 have1804.38 come1804.45 out1804.7 as,1805.02 you1805.65 know,1805.73 98%1806.45 homology1807.1 to1807.58 Bacillus1807.73 anthracis?1808.13 So1808.7 is1809.17 the1809.34 SecurDNA1809.49 basically1810.21 taking1810.62 stuff1810.93 and1811.17 just1811.34 blasting1811.58 it1811.89 and1812.13 have1812.45 some1812.7 algorithm1812.93 to1813.41 look1813.58 for1813.73 RG1815.89 3s?1816.45
1816.45 MOLDES1816.45 -1816.45 Yes.1816.45 So1817.01 what1817.17 SecurDNA1817.49 does1818.53 is1818.85 it's1819.33 a1819.57 blast,1819.65 and1820.13 they1820.53 look1820.85 for1821.09 301822.13 base1822.53 per1822.77 matching1823.09 to1824.45 organisms.1824.93
1828.02 LIEBERMAN1828.02 -1828.02 And1828.02 then1828.02 what1828.02 genes,1828.35 because1829.22 all1829.63 of1829.87 these1829.94 sequences1830.27 you1830.66 said1830.83 were1830.98 just1831.3 promoters,1831.63 Right?1832.27
1833.07 MOLDES1833.07 -1833.07 Mhmm.1833.07 Yeah.1833.54
1833.54 MOLDES1833.54 -1833.54 Do1834.35 you1834.51 know1834.59 what1834.83 genes1835.14 these1835.46 promoters1835.63 are1836.11 associated1836.35 with1836.9 in1837.07 the1837.14 risk1837.3 group1837.54 31837.87 organisms?1838.02
1839.22 MOLDES1839.22 -1839.22 Yes.1839.63
1840.27 LIEBERMAN1840.27 -1840.27 It1840.27 matters1840.42 if1840.83 it's1840.98 a,1841.3 quote,1841.46 unquote,1841.7 virulence1842.11 factor1842.66 or1843.22 a1843.46 resistance1843.84 gene.1844.72 But1845.04 if1845.28 it's1845.44 not,1845.6 then1846 it's1846.48 still,1846.72 you're1847.12 considering1847.36 it1847.92 okay1848 to1848.24 work1848.32 with?1848.56
1850 MOLDES1850 -1850 So1850 if1850.32 it's1850.56 a1850.88 promoter,1851.28 and1853.04 there's1853.84 no1854.24 link1854.48 to1854.96 the,1855.6 again,1856.32 virulence1858.81 factor,1858.97 we1858.97 are1858.97 considering1859.21 it.1859.68 The1861.21 problem1862.09 was1862.48 the1862.81 second1863.13 variant1863.45 was1864.09 misannotated,1864.81 and1866.09 it's1866.73 not1867.29 just1867.53 the1867.77 UTR,1868.01 and1868.57 it1868.97 encodes1869.13 for1869.68 a1870.9 portion1870.98 of1871.38 the1871.54 initial1873.86 part1874.34 of1874.5 the1874.66 of1875.14 the1875.46 CAB-D,1875.62 gene.1876.9
1878.5 LIEBERMAN1878.5 -1878.5 I'm1878.5 sorry,1879.06 the1879.38 which1879.38 gene?1879.7
1881.14 MOLDES1881.14 -1881.14 The1881.14 encapsulation.1881.3
1883.86 LIEBERMAN1883.86 -1883.86 Okay.1883.86 So1885.67 it's1885.91 not1886.08 like1886.32 lethal1886.56 toxin1886.96 or1887.43 something,1888.32 it's1888.56 just1888.56 the1888.88 capsule1889.04 protein?1889.91
1890.39 MOLDES1890.39 -1890.39 Yes.1890.39 Yes.1890.96
1895.67 LIEBERMAN1895.67 -1895.67 Okay.1895.67 So1896.15 your1896.39 goals1896.72 in1897.2 using1897.52 these1898.93 promoters1899.09 going1899.73 forward,1900.29 I1901.57 guess,1901.73 can1901.97 you1902.13 just1902.29 remind1902.61 us1902.93 you1903.81 have1903.97 these1904.21 promoters,1904.45 and1905.01 they're1905.81 from1906.05 various1906.21 organisms,1906.69 RG1909.09 1s,1909.41 RG1909.41 2s,1909.41 RG1909.41 3s1909.41 now.1909.41 And1909.89 what1910.13 is1910.37 your1910.53 company1910.69 using1911.49 the1911.81 promoters1911.97 for1912.53 your1913.57 context?1913.8
1915.64 MOLDES1915.64 -1915.64 So,1915.64 in1916.92 this1917.16 case,1917.33 the1917.57 promoters1917.8 we1918.44 are1918.68 using1918.85 them1920.13 to1921.57 lead1921.57 the1921.88 expression1922.04 of1922.85 transposase1924.92 and1925.8 antibiotic1925.8 markers1926.52 so1927.48 that1927.72 we1928.2 can1928.36 generate1928.6 TN,1930.68 whole1934.2 genome1934.44 TN1935.08 libraries1937.56 for1939.16 functional1939.4 annotation.1940.36
1942.35 LIEBERMAN1942.35 -1942.35 And1942.35 so1942.51 the1942.66 antibiotic1942.98 markers1943.94 that1945.07 are1945.3 gonna1945.38 be1945.63 associated1945.78 are1946.66 not1947.3 anything1947.63 exotic1948.26 for1948.74 antibiotics,1949.63 right?1949.87 We're1949.87 talking1950.02 about,1950.35 okay.1951.38
1951.38 MOLDES1951.38 -1951.38 We're1951.38 talking1951.63 about1951.94 pannamycin,1952.35 ampicillin,1953.22 chloramphenicol,1955.07 like,1956.11 very1956.89 regular1957.85 antibiotics,1959.45 nothing1959.77 exotic.1959.77
1961.21 LIEBERMAN1961.21 -1961.21 Okay.1961.21 Because,1962.01 obviously1962.41 I1964.49 mean,1964.57 bacillus1964.97 is1965.61 obviously1965.69 very1966.09 susceptible1966.41 to1967.13 penicillin1967.37 or,1968.41 you1968.57 know,1968.73 most1968.97 first1969.29 line1969.61 antibiotics.1969.93 So1970.65 I1970.81 guess1970.89 the1971.29 the1972.59 area1972.66 of1972.98 potential1973.14 concern1973.63 here1974.02 is1974.27 even1974.42 though1974.66 you're1974.74 using1974.9 kind1975.3 of1975.46 run1975.7 of1975.87 the1976.02 mill1976.18 antibiotics1978.27 common1978.9 for1979.38 molecular1979.87 biology1980.27 applications,1980.66 what1981.38 happens1981.63 if1982.83 that1983.07 whole1983.3 sequence1983.54 gets1984.02 out1984.27 and1984.78 gets1985.1 back1985.34 into1985.66 one1986.54 of1986.78 your,1986.94 you1988.14 have1988.3 a1988.54 whole1988.62 long1988.78 list1989.02 of1989.34 things,1989.9 you1990.14 know,1990.14 you1990.3 have1990.38 Burkholderia1990.94 that1991.26 are1991.5 not1991.66 RG1991.9 3s1992.22 or1992.54 bacilli1993.02 that1993.58 are1993.74 not1993.9 RG1994.06 3s,1995.5 is1995.66 there1995.66 potential1996.54 for1997.34 reversion1998.54 there?1999.26
2002.52 MOLDES2002.52 -2002.52 So2002.52 we2003.23 always2003.71 use2004.28 pure2005.15 cultures,2006.67 we2007.39 never2007.39 mix2007.88 the2008.28 cultures.2008.84 But,2009.71 in2010.28 any2010.52 case,2010.76 we2011.15 use2011.32 these2011.63 libraries2011.88 for2012.76 all2013.39 the2013.63 different2013.79 organisms.2014.36 So2020.43 I2020.55 guess2020.67 the2020.91
2021.31 LIEBERMAN2021.31 -2021.31 Theoretically,2021.31 somebody2021.95 drops2022.35 a2022.99 beaker2023.07 in2023.63 the2023.79 biosafety2024.03 cabinet,2024.67 hopefully,2026.11 in2026.59 the2026.67 biosafety2026.91 cabinet,2031.08 and2031.32 somebody2031.32 else2031.71 didn't2031.95 quite2032.36 clean2032.67 up2032.99 something,2033.23 and2033.63 we're2033.79 talking2033.95 about2034.28 a2034.52 bacillus,2034.6 which2034.99 is2035.15 a2035.39 spore2035.55 former,2036.76 and2036.91 it2036.91 decides2037.08 to2037.63 go2038.36 back2038.52 into2038.67 its2038.91 vegetative2039.15 state.2039.79 Like,2040.03 I2040.36 know2040.67 that2040.84 we're,2041.08 you2041.39 know,2041.47 we're2041.71 playing2041.88 out2042.28 the2042.52 minute2042.99 possibilities2043.47 here,2044.12 but,2044.36 right,2044.52 these2044.67 are2044.84 kind2045.08 of2045.23 the2045.39 thought2045.55 exercises2046.15 that2046.31 we2046.77 wanna2047.08 have,2047.69 right?2047.99
2047.99 MOLDES2047.99 -2047.99 Yeah.2047.99
2048.2 LIEBERMAN2048.2 -2048.2 So,2048.2 like2048.42
2049.27 MOLDES2049.27 -2049.27 I2049.27 would2049.27 say2049.48 that2049.7 there's2049.91 a2050.15 chance,2050.23 but2050.55 this2050.79 phenomenon2051.03 is2051.19 really2051.43 not2051.71 special2051.99 to2052.27 just2052.55 us2061.61 and2061.61 it2061.61 has2061.78 not2062.18 been2062.57 seen2063.22 in2063.86 microbiology,2065.38 and2065.7 everyone2065.7 uses2066.26 these2066.97 antibiotics.2067.3 So2068.26 well,2069.3 everyone2069.7 uses2070.18 these2070.57 antibiotic2070.97 resistance2071.93 and2072.66 different2073.61 strains.2074.57 So,2078.35 we2078.67 don't2078.75 see2078.99 that2080.27 that2080.83 is2081.07 going2081.31 to2081.63 affect2082.27 and2082.75 impact2083.07 us,2083.71 like,2084.59 specifically.2086.51 But2087.31 we2087.63 always2087.95 try2088.43 to2088.75 put2088.91 all2089.23 the2089.47 measures2089.71 in2090.19 place2090.43 so2091.07 that2091.31 we2092.81 always2093.2 emphasize2093.45 the2093.93 fact2094.16 that2094.41 we2094.49 need2094.72 to2094.97 clean2095.05 after2095.37 ourselves2095.68 because2096.24 we2096.72 are2096.97 working2097.2 with2097.61 so2097.93 many2098.16 different2098.41 organisms.2098.89 As2099.77 you2100.09 mentioned,2100.24 Bacillus2102.33 spores,2102.97 so2102.97 we2102.97 are2103.2 really,2103.37 really2103.61 careful2103.93 with2104.64 all2106.86 the2107.18 methods2107.5 that2107.82 we2107.98 have2108.22 in2108.46 place2108.54 to2109.58 make2109.98 sure2110.14 that2110.3 they2110.54 disinfect2110.86 properly.2113.82 And,2114.62 also,2114.94 we2116.22 have2116.46 the2116.94 safety2117.66 consultant2118.06 that2118.7 help2120.23 us2120.47 flag2120.8 if2121.19 there2121.36 is2121.51 any2121.67 concern2121.99 with2122.55 our,2123.51 disinfection2125.03 methods.2125.67 And2126.32 that's2126.55 why2126.88 we2127.11 also2127.36 have2127.67 the2128.07 internal2128.39 review,2129.03 agent2130.55 review2130.95 in2131.43 place2131.67 so2131.99 that2132.15 we2132.39 can2132.47 identify2132.71 these2134.26 potential2134.58 issues2135.14 before2135.62 we2136.02 even2136.18 start2136.42 working2136.66 with2136.98 them.2137.22
2140.42 LIEBERMAN2140.42 -2140.42 Okay.2140.42 No.2141.86 I2142.18 mean,2142.26 I2142.42 think2142.74 these2142.9 all2143.14 sound2143.3 like2143.46 really2143.62 good2143.86 precautions.2144.1 The2144.9 only2145.06 other2145.22 thing2145.38 I'll2145.62 just2145.7 add2145.94 is,2146.1 that2146.26 table2146.42 that2146.66 you2146.82 showed2146.98 with2147.14 all2147.38 the2147.46 new2147.62 agents2147.86 that2148.18 you2148.34 are2148.58 adding.2148.74 I2149.45 don't2149.53 think2149.76 we2149.84 got2150.01 a2150.24 copy2150.32 of2150.64 that2150.8 separately.2151.05 So2151.53 if2151.68 you2151.93 can2152.01 please2152.16 get2152.49 that2153.36 uploaded2153.53 to2153.93 OpenGov,2154.09 because2154.64 when2154.97 this2155.13 amendment2155.36 was2155.84 submitted,2156.09 it2156.57 was2156.72 very2157.13 much2157.45 like2157.68 we're2157.84 talking2158.09 about2158.32 RG2158.57 32158.89 promoters2159.05 and2159.61 not2159.76 like2159.93 we're2160.09 adding2160.32 this2160.64 table2160.89 of2161.28 RG1s,2161.93 but2162.32 just2162.8 quickly2163.13 send.2163.53 I2163.76 think2163.84 that2164.01 would2164.16 be2164.32 helpful.2164.49
2165.42 MOLDES2165.42 -2165.42 It2165.42 is2165.58 part2165.74 of2166.06 the2166.46 full2166.78 list.2167.18 It's2168.3 true2168.62 that2168.86 I2169.02 didn't2169.18 separate,2169.5 specifically2170.7 the2171.34 one2171.5 that2171.9 we2172.14 were2172.22 adding.2172.54 I2172.78 just2172.94 submitted2173.5 the2173.98 full2174.14 list,2174.38 but2174.62 it2174.86 is2175.02 part2175.18 of2175.42 the2175.5 full2175.66 list.2175.9 Sorry.2176.14
2177.1 LIEBERMAN2177.1 -2177.1 Yeah.2177.1 No2177.34 problem.2177.5 If2177.74 you2177.82 can2177.9 just2177.98 submit2178.22 it2178.54 separately2178.62 as,2179.02 like,2179.26 you2179.63 know,2179.7 new2179.94 organisms2180.18 for2180.74 the2180.98 October2181.22 242181.63 amendment,2182.03 that's2182.42 fine.2182.66 And2182.82 then2182.98 when2183.22 the2183.39 renewal2183.55 rolls2183.94 around2184.26 in,2184.51 you2184.98 know,2185.14 three2185.39 months,2185.55 you2185.86 can2185.94 submit2186.11 it2186.42 as2186.51 a2186.66 giant2186.74 list2187.07 again,2187.22 and2187.46 that's2187.86 fine.2188.11
2189.14 MOLDES2189.14 -2189.14 Yep.2189.14 Yeah.2189.46 Will2189.86 do.2190.03
2190.26 LIEBERMAN2190.26 -2190.26 Thank2190.26 you.2190.51
2191.3 PARSONS2191.3 -2191.3 Yep.2191.3 Great.2193.27 Thank2193.67 you,2193.83 Mia.2193.99 So2196.79 I2197.03 have2197.19 a2197.59 kind2197.67 of2197.91 a2198.07 question,2198.23 more2198.95 of2199.19 a2200.23 process2200.39 understanding.2206.09 The2207.05 computer2207.05 model,2207.05 right,2207.05 figuring,2207.05 doing2207.05 the2207.53 analysis,2208.24 like,2208.48 is2208.48 this2208.64 coming2209.05 from2209.28 a2209.53 risk2209.68 group2209.92 32210.16 or2210.32 risk2210.57 group2210.88 4?2211.05 What2211.53 I2211.68 didn't2211.76 understand2212.09 in2212.8 the2212.96 amendment,2213.2 so2213.68 not2213.92 your2214.09 presentation,2214.32 but2214.88 in2215.13 the2216.24 documents2216.4 that2216.8 were2216.96 uploaded,2218.24 is2218.48 this2218.48 software2218.8 used2219.68 after2220.66 material2221.38 has2221.86 been2222.18 brought2222.42 on2222.82 onto2223.14 site?2223.54
SHOW NON-ESSENTIAL DIALOGUE
2229.54 PARSONS2229.54 -2229.54 Or2229.54 do2229.78 like,2230.02 you2230.18 already2230.42 know2230.74 the2231.14 sequence2231.38 and2231.86 you're2232.1 gonna2232.26 run2232.58 it2232.74 through2232.98 this2233.97 program2234.68 before2235.33 you2235.64 order2235.97 it2236.29 and2236.45 or2236.77 have2237.24 it2237.49 received2237.64 on-site?2238.13
2240.45 MOLDES2240.45 -2240.45 So,2240.45 what2241.64 we2241.89 did2242.13 is2242.45 we2242.85 analyzed2243.01 every2243.64 single2243.89 sequence2245.64 that2246.13 we2246.36 had2246.53 already2247.41 in2247.81 house.2247.97 But2248.45 the2248.85 point2249.75 is,2250.15 we2250.55 want2250.71 to2251.03 use2251.19 it2251.51 way2251.75 before.2252.07 Like,2252.47 the2252.79 moment2252.95 that2253.27 we,2253.43 at2256.87 the2257.03 inception2257.19 of2257.75 the2257.99 project,2258.07 whenever2258.55 we2258.95 have2259.11 the2259.27 sequence,2259.43 we2260.23 want2260.39 to2260.63 run2260.79 it.2260.95
2261.93 PARSONS2261.93 -2261.93 Gotcha.2261.93 Okay.2262.41 So2262.89 my2263.2 question2263.36 then,2263.61 so2264.01 we've2264.32 been2264.57 talking2264.72 about2265.05 risk2265.36 groups2265.68 12266.01 through2266.24 3,2266.49 which2267.68 makes2268.01 sense,2268.81 but2269.05 in2269.05 the2269.2 amendment,2270.64 risk2271.53 group2271.77 42272.09 is2272.41 mentioned,2272.57 like,2272.97 you2273.2 know,2273.36 because2273.53 you2274.57 are,2274.64 you2274.72 know,2274.97 analyzing2276.24 any2277.74 potential.2277.9 So2278.86 what2279.74 would,2279.98 is2280.54 there2280.7 an2281.58 SOP2282.06 or2283.02 a2283.82 procedure2284.06 in2285.34 place2285.58 where,2286.14 in2287.02 the2287.18 hypothetical,2287.42 that2288.22 you2288.54 ran2288.86 this2289.18 program2289.42 and2290.54 it2291.1 was2292.57 a2292.8 positive2292.97 hit2293.45 for2293.68 the2293.84 lack2294.01 of2294.24 a2294.41 better2294.49 phrase2295.36 coming2296.16 from2296.49 a2296.72 risk2296.8 group2297.05 42297.36 material?2298.64 Like,2299.13 what2299.36 would2299.77 happen?2300.01
2302.57 MOLDES2302.57 -2302.57 We2302.57 don't2302.72 have2303.05 any2303.29 sequence,2303.61 any2304.01 risk2304.32 group2304.57 42304.8 sequence.2305.13 And2305.61 the2305.77 moment2305.93 that,2306.95 because2307.19 we're2307.43 going2307.67 to2307.99 run2308.15 them2308.39 beforehand,2308.63 the2309.59 moment2309.83 that2310.07 we2310.23 identify2310.47 a2311.43 risk2311.67 group2311.91 4,2312.07 we're2312.55 going2312.79 to2313.19 stop2313.91 using2315.35 that.2315.83 Like,2316.55 not2316.95 even2317.19 using2317.43 it,2318.07 like,2319.14 we2319.14 will2319.39 not2319.55 select2319.95 any2320.51 organisms2320.99 that2321.7 are2321.86 risk2322.51 group2322.83 4.2323.47
2324.11 PARSONS2324.11 -2324.11 Gotcha.2324.11 Okay.2324.66 That's2324.99 what2325.22 I2325.39 just2325.47 wanted2325.7 to2326.03 confirm,2326.18 because,2326.91 like2328.27 I2328.51 said,2328.59 everything2328.83 was2329.22 up2330.43 to2330.59 risk2330.83 group2331.07 32331.39 but2331.55 in2331.79 the2331.95 paperwork2332.83 that2333.31 was2333.47 submitted,2333.63 risk2334.74 group2334.9 42335.14 is2335.3 mentioned.2335.54 Okay.2336.02 Alright.2336.58 So2336.82 that's2336.9
2337.7 LIEBERMAN2337.7 -2337.7 Brad,2337.7 which2338.1 document2338.34 was2338.74 that2338.9 mentioned2339.06 on?2339.38
2339.94 PARSONS2339.94 -2339.94 I2339.94 didn't2340.42 note2341.22 that2341.46 in2341.7 my2341.86 notes.2342.1 I2342.66 just2342.82 wrote,2343.7 so2344.26 what2344.5 happens2344.66 if2345.06 the2345.22 software2345.38 identifies2345.78 risk2346.5 group2346.74 42347.06 material,2347.86 is2348.02 the2348.02 stuff2348.18 already2348.5 on-site?2348.9 So2349.8 somewhere2350.03 in2350.76 either2351.8 the2352.19 reason2352.36 for2352.68 the2352.84 amendment2352.99 or2353.95 the2354.36 scope2354.68 of2354.91 work,2355.16 I'm2355.95 guessing2356.19 it's2356.51 one2356.76 of2356.91 those2356.99 two2357.16 documents,2357.39 certainly2357.8 not2358.11 the2358.28 EAP2358.51 or,2358.84 you2359.07 know,2359.16 any2359.39 of2359.55 the2359.71 other2359.8 stuff,2361.79 it's2362.11 where2362.11 it2362.43 mentions2362.67 risk2363.15 group2363.39 4.2363.63 That's2364.27 the2364.51 only2364.59 reason2364.83 why2364.99 it2365.15 caught2365.31 my2365.47 attention,2365.63 because2366.03 it2366.27 was2366.71 like,2367.15 oh,2367.59 0,2368.03 I2368.35 remember2368.51 this2368.91 from2369.15 the2369.31 emails2369.47 in2369.87 early2370.03 August2370.35 when2370.75 we2370.83 were2370.99 talking2371.07 about2371.31 risk2371.55 group2371.79 3,2372.11 which2372.51 you2372.91 know?2373.07 And2373.39 to,2373.63 you2373.79 know,2373.87 to2374.03 echo,2374.19 what2374.99 other2375.15 people2375.56 have2375.72 said,2375.8 we2375.88 really2376.2 do2376.43 appreciate,2376.68 and2377.39 respect,2377.8 and2378.76 thank2379.08 you2379.32 for2379.64 the2381.16 openness2381.39 and2382.28 the2383.24 quick2384.11 action.2384.43 You2386.52 know,2386.76 contacting2388.22 the2388.62 FBI2388.86 is2389.5 never2389.74 a2390.06 comfortable2390.3 thing2390.86 to2391.18 do.2391.26 And2393.1 so2393.42 looking2394.06 at2394.38 that2394.54 timeline,2394.78 you2395.26 know,2395.58 you2395.66 did2395.74 that,2396.54 you're2396.78 doing2397.02 all2397.42 the2397.74 right2397.98 things,2398.22 and2398.54 it's2399.42 not2399.74 always2399.98 easy2400.38 to2400.78 do2400.94 the2401.18 right2401.34 thing.2401.5 So,2402.77 again,2403.24 thank2403.64 you2403.81 very2403.97 much.2404.13
2405.64 MOLDES2405.64 -2405.64 Thanks.2405.64
SHOW NON-ESSENTIAL DIALOGUE
2415.97 MCEWAN2415.97 -2415.97 I2415.97 mean,2416.13 this2416.21 isn't2416.37 a2416.61 question,2416.69 but2417.01 just2417.17 right.2417.33 Like,2417.49 getting2418.53 a2418.85 sequence2419.09 from2419.65 a2419.89 paper2420.05 and2420.45 creating,2420.69 you2421.49 know,2421.65 a2421.89 promoter,2422.13 I2423.89 personally2424.45 have2424.93 done2425.09 countless2425.57 times2426.29 without2426.85 sort2427.57 of2427.73 this2427.97 extra2428.21 layer2428.61 view.2428.93 So,2429.33 you2430.3 know,2430.38 reassuring,2430.61 I2431.18 guess,2431.26 anyone2431.66 who2432.53 might2432.78 be2432.93 watching2433.09 this2433.34 from2433.57 the2433.66 public.2433.82 Like,2434.14 this2434.3 is2434.45 a2434.61 very2434.7 standard2434.93 procedure,2435.41 and2436.3 this2436.53 is2436.7 sort2436.86 of2437.01 an2437.09 extra2437.34 new2437.89 layer2438.14 of2438.86 safety2439.09 that's2439.49 being2439.74 added2440.93 that2441.74 is2441.74 fantastic2441.97 that2442.53 we2442.7 can2442.78 do2442.93 that.2443.09
2445.2 PARSONS2445.2 -2445.2 Yeah.2445.2 So2445.36 which2445.52 leads2445.84 me2446.16 to2446.4 my2446.48 opinion2447.28 that2447.68 this2447.92 doesn't2448.08 really2448.32 need2448.56 to2448.68 go2448.8 to2449.04 the2449.2 board2449.36 of2449.6 health2449.68 because2450 this2450.48 is2450.72 above2450.96 and2451.28 beyond.2451.44 And2452.8 then2452.96 the2453.44 transparency2453.68 has2454.48 been,2454.72 well,2455.36 crystal2456.4 clear2456.88 since2457.36 day2457.76 one,2458.64 and2458.8 there's2458.8 no2459.12 real2459.36 change,2459.68 I2460.08 think.2460.24 If2461.2 you2461.36 were2461.53 looking2463.53 to2463.76 bring2463.84 on2464.09 full2464.41 risk2464.89 group2465.13 32465.45 material,2467.05 then2467.61 obviously,2467.93 that's2468.89 a2469.13 different2469.28 conversation.2469.68 But2470.24 we're2470.41 talking2470.57 about2470.89 sections2471.28 and2471.76 blah2472.8 blah2473.05 blah.2473.28 Things2474.16 that2474.4 Rob2474.72 and2474.88 I2475.04 kind2475.92 of2476.32 understand2476.32 but2476.8 don't2477.04 fully,2477.36 and2478.32 trust2478.72 Mia,2479.2 Deb,2479.84 and2480.16 Tim2480.4 to2480.8 run2480.96 with2481.2 that.2481.44 So,2483.52 yeah,2484.08 thank2484.56 you2484.8 very2485.04 much.2485.28 And2488.27 I2488.43 know2488.59 I2488.74 seem2488.91 like2489.07 I2489.22 asked2489.39 this.2489.55 Mia,2490.43 do2490.74 we2490.91 approve2491.07 amendments,2491.47 or2491.86 we2492.03 just2492.18 accept2492.43 amendments?2492.74
2495.39 LIEBERMAN2495.39 -2495.39 I2495.39 don't2495.47 know2495.7 what2495.86 the2496.03 proper2496.18 term2496.59 is.2496.83 I2497.07 think2497.14 it's2498.27 accept.2498.66
2499.63 PARSONS2499.63 -2499.63 Yeah.2499.63 Okay.2500.41 Do2500.65 we2500.89 need2501.05 to2501.21 vote2501.29
2501.37 LIEBERMAN2501.37 -2501.37 By2502.33 the2502.41 way,2502.57 did2502.73 you2502.89 contact2503.05 the2503.37 author2503.53 of2503.65 the2503.77 paper2503.85 to2504.09 let2504.25 them2504.33 know2504.49 they'd2504.57 misannotated2505.05 the2505.45 gene?2505.53
2506.01 PARSONS2506.01 -2506.01 That2506.01 was2506.33 my2506.65 other2506.81 question.2507.13
2509.53 MOLDES2509.53 -2509.53 No.2509.53 No.2510.81 We2511.05 haven't2511.21 contacted2511.53 anybody.2512.17
2512.81 LIEBERMAN2512.81 -2512.81 Okay.2512.81 That2513.21 might2513.45 just2513.61 be2514.66 something2514.91 worth2515.22 worthwhile2515.7 to2516.18 do2516.26 so2516.59 that2516.74 nobody2516.91 else2517.22 ends2517.46 up2517.63 in2517.78 this2517.95 situation.2518.26
2519.39 MOLDES2519.39 -2519.39 Yeah.2519.39
2520.03 PARSONS2520.03 -2520.03 Well,2520.03 because2520.18 it's2520.43 been2520.66 public2520.98 for2521.39 what,2521.63 five2521.86 years2522.11 now.2522.34 So2522.66 that's2522.91 a2523.46 long2523.7 time,2524.82 especially2525.07 in2525.46 microbiology,2526.43 that's2526.74 forever.2526.74 Alright.2532.55 So2532.79 I2532.95 don't2533.03 think2533.19 there's2533.43 any2533.59 further2533.75 action,2534.07 for2534.87 the2535.03 amendment2535.27 on2535.67 behalf2535.83 of2536.15 the2536.23 Watertown2536.39 Biosafety2536.79 Committee.2537.35 Like2538.07 Mia2538.23 said,2538.55 though,2538.79 when2539.75 it2539.99 comes2540.07 time2540.39 for2540.63 renewal2541.03 in2542.22 the2542.39 winter,2542.94 you2543.51 can2543.66 do2543.91 one2544.14 big2544.46 list,2546.86 you2546.94 know,2547.03 because2547.18 now2547.43 there2548.63 are2548.86 two2548.94 different2549.18 lists2549.51 but2550.78 you2551.03 can2551.18 combine2551.43 them2551.74 for2552.63 the2552.78 renewal.2553.03
2555.68 MOLDES2555.68 -2555.68 Okay.2555.68 Yeah.2556.8 I2557.04 will2557.28 definitely2557.92 send2558.48 you2558.72 the2559.2 shortlist.2559.76
2561.28 LIEBERMAN2561.28 -2561.28 Okay.2561.28 Thanks.2561.6
2563.44 PARSONS2563.44 -2563.44 Yeah.2563.44 And2563.68 you,2563.84 you2564 know2564.08 what,2565.52 yeah.2565.76 OpenGov,2565.76 yeah.2565.76 So2565.76 I2565.84 mean2565.92 yeah,2566.8 you2566.96 can2566.96 go2567.2 that2567.36 route.2567.6
SHOW NON-ESSENTIAL DIALOGUE
2581.86 FOLEY2581.86 -2581.86 Can2581.86 I2582.03 ask2582.26 a2582.51 question,2582.66 to2587.14 clarify?2587.38 Can2587.38 we2587.38 go2587.54 back2587.7 to2587.86 Ralph's2588.1 question2588.58 about2589.22 why2590.82 did2591.06 you2591.3 take2591.46 this2591.7 path?2591.94 And2593.22 she2593.46 said2593.7 we2594.1 weren't2594.26 permitted2595.22 for2595.94 something.2596.34 I2596.98 don't2597.14 know2597.38 what2597.94 that2598.18 something2598.42 is.2598.82
2599.68 LIEBERMAN2599.68 -2599.68 So2599.68 I2600.09 think2600.48 maybe2600.72 the2601.05 best2601.13 way2601.36 to2601.53 describe2601.68 it2602.01 for2602.16 the2602.32 minutes2602.48 is2602.89 that2603.05 they2604.24 hadn't2604.48 previously2604.8 sought2606.48 approval2606.8 to2607.36 use2607.53 gene2608.09 sequences2608.57 from2609.2 risk2609.68 group2609.93 32610.32 organisms.2610.57 Zaira,2612.02 please2612.34 correct2612.9 me2613.22 if2613.46 I'm2613.54 screwing2613.62 with2613.94 that.2614.1 And2615.3 so,2615.78 they2616.9 identified2617.62 that2618.42 they2618.74 had2618.9 inadvertently2622.9 ordered2622.9 some2623.46 promoter2623.78 sequences2624.26 that2624.82 turned2625.06 out2625.3 to2625.54 be2625.62 from2625.78 risk2626.02 group2626.26 32626.66 organisms,2627.59 and2628.07 this2628.32 is2628.47 part2628.72 of2629.11 their2629.51 due2630.64 diligence2630.95 to2631.59 ensure2631.84 that2632.23 there2632.39 is2632.55 a2633.76 procedure2633.99 for2634.55 identifying2634.8 and2635.28 using2635.43 this2635.68 if2635.99 they2636.16 choose2636.32 to2636.55 work2636.64 with2636.88 them.2637.03
2637.84 FOLEY2637.84 -2637.84 Okay.2637.84
2638.64 LIEBERMAN2638.64 -2638.64 That2638.64 sum2638.88 it2639.11 up?2639.28
2655.55 MOLDES2655.55 -2655.55 Yes.2655.55
2655.55 LIEBERMAN2655.55 -2655.55 Did2655.55 I2655.55 miss2655.55 anything?2655.55
2655.55 MOLDES2655.55 -2655.55 No.2655.55
2655.8 MCEWAN2655.8 -2655.8 Can2655.8 we2655.8 put2655.8 in2655.8 the2655.8 minutes2655.8 that2655.8 these2655.8 were2655.8 low2655.8 risk2655.8 ones2655.8 just2655.8 so2655.8 people2655.8 don't2655.8 see2655.8 risk2655.8 group2655.8 32655.8 and2655.8 start2655.8 to2655.8 be2655.95 concerned?2657.07
2658.11 PARSONS2658.11 -2658.11 Right.2658.11
2658.11 LIEBERMAN2658.11 -2658.11 Promoters2658.11 for2658.76 non2658.99 virulence2660.59 factor2661.23 genes2661.64 and2662.51 non2662.68 antibiotic2663.16 resistance2663.88 markers.2664.51 You2665.47 can2665.64 specify2666.11 that.2666.59
2667.23 PARSONS2667.23 -2667.23 And2667.23 not,2667.47 like,2668.11 with2668.43 bold2668.91 upper2669.98 case2670.3 biosafety2671.02 level2671.74 32672.22 work?2672.54
2673.9 MOLDES2673.9 -2673.9 Yes.2673.9 No.2674.38 No2675.82 risk2676.06 group2676.06 32676.3 or2676.54 any2676.7 signs.2677.02
2677.66 PARSONS2677.66 -2677.66 Like,2677.66 not2677.9 even2678.14 close.2678.46 Risk2678.78 group2679.1 3,2679.42 risk2679.98 groups2680.22 are2680.46 different2680.62 than2680.94 biosafety2681.18 levels,2681.82 and,2682.7 yeah,2683.02 we2683.34 don't,2684.03 but,2684.26 Maureen,2684.26 we'll2684.51 make2684.74 sure2684.98 we2685.22 review2685.39 your2687.3 draft2687.63 to2688.11 make2688.26 sure2688.42 that2688.74 BSL2689.55 32690.18 is2690.59 not2690.9 in2692.66 those2692.82 minutes2693.14 because2693.39 this2693.7 is2693.94 not2694.18 what2694.42 we're2694.59 approving.2694.9 We're2695.39 not2695.63 approving2695.78 anything,2696.18 actually,2696.51 but2697.3 this2697.46 is2697.63 not2697.78 what2697.94 we're2698.11 discussing2698.34 at2699.07 all.2699.14
2699.77 FOLEY2699.77 -2699.77 Okay.2699.77 I2700.89 had2701.45 a2702.17 hard2702.33 time2702.57 following2702.81 this.2703.21
2703.93 PARSONS2703.93 -2703.93 Yeah.2703.93 This2704.09 was2704.33 a2704.49 tough2704.65 one.2704.81 Like,2705.05 when2705.29 I2705.45 read,2706.17 I2707.77 was2707.85 like,2708.09 wow.2708.41 I'm2708.65 gonna2708.81 lean2709.13 heavy2709.29 on,2709.69 Mia,2710.25 Deb,2710.57 and2710.81 Tim2710.97 on2711.21 this2711.37 one.2711.53 And2711.69 then2711.85 when2712.01 I2712.09 got2712.25 the2712.33 email2712.49 from2712.81 Tim2712.97 that2713.21 he2713.37 wasn't2713.53 gonna2713.85 be2714.25 here2714.41 tonight,2714.73 I2715.05 was2715.21 like,2715.37 okay.2715.66 We're2716.07 down2716.46 to2716.7 two2716.86 biologists.2717.18 What's,2719.51 I2719.74 hope2719.82 they2720.07 both2720.95 show2721.51 up2721.74 because2723.11 I2723.43 just2723.59 have2723.74 this2723.98 computer2724.22 software2725.03 program2725.66 question.2726.22
2731.87 FOLEY2732.83 -2732.83 I2732.83 didn't2732.99 have2733.31 that,2733.95 so.2736.03
2736.03 PARSONS2736.03 -2736.03 No2736.03 chemistry2736.35 involved2736.83 here,2738.75 well,2739.07 some2739.07 biochem,2739.31 but2739.79 not2739.95 chemistry.2740.19 But,2740.75 alright.2742.11 Great.2742.51 So2743.39 any2744.11 further2744.34 questions,2744.59 Maureen,2744.98 for2745.39 the2745.55 minutes?2745.63 Because,2746.43 yes,2746.74 this2747.07 is2747.22 a2747.7 tough2747.86 one.2748.11
2751.86 FOLES2751.86 -2751.86 No.2751.86 I'll2752.51 use2753.78 Google2754.11 tomorrow.2754.51
2755.75 PARSONS2755.75 -2755.75 But,2755.75 also,2755.83 bounce2756.47 it2756.95 off2756.95 us,2757.11 right,2757.35 we'll2757.83 get2758.07 it2758.23 right.2758.31 As2758.71 a2759.11 as2759.51 a2759.83 committee,2759.99 we'll2760.39 get2760.55 this2760.79 right.2761.03
2761.59 LIEBERMAN2761.59 -2761.59 Yeah.2761.59 But2761.59 let's2761.75 do2762.15 it,2762.39 like,2762.55 this2762.79 week2762.95 and2763.27 not,2763.43 like,2763.59 three2763.83 weeks2763.99 from2764.23 now2764.47 when2764.55 I2764.63 don't2764.79 remember2764.95 what2765.19 we2765.35 talked2765.51 about.2765.75
2766.55 FOLEY2766.55 -2766.55 Exactly.2766.55 I2767.11 tried2767.35 to2767.67 do2767.83 them2767.99 the2768.15 next.2768.31
2770.63 PARSONS2770.63 -2770.63 Alright.2770.63 Perfect.2771.74 Alright.2772.07 Well,2772.39 thank2772.7 you,2772.86 for2774.3 your2774.39 presentation2774.63 and2775.43 your2775.51 time2775.66 and2776.78 your2776.86 transparency2777.43 and2778.3 being2778.46 here2778.7 this2778.86 evening.2779.03 You're2780.22 free2780.55 to2780.7 go.2780.86 Thank2781.66 you2781.91 very2782.07 much.2782.3 Best2782.55 of2782.78 luck2782.86 with2783.03 your2783.18 research.2783.34 You2785.8 know,2785.88 to2786.04 echo2786.28 other2787 people,2787.24 you2787.56 might2787.8 wanna2788.04 just,2788.36 like,2788.68 in2789 a2789.16 professional2790.12 but2790.84 firm2791.96 way,2792.36 email2794.6 Kim2795.08 and2796.28 say,2796.52 hey.2796.84 But2800.41 I2800.64 know2800.8 that's2800.96 tough,2801.53 right?2801.76 There's2801.76 respect2802.09 and2802.48 it's2802.8 the2803.61 world2803.76 of2804.01 academia,2804.16 but2804.8 it's2804.96 kind2805.13 of2805.28 a2805.45 big2805.53 deal,2806.89 so.2807.61
2807.61 MCEWAN2807.61 -2807.61 I2807.61 mean,2807.76 I2808.24 think2808.32 the2808.72 bigger2809.05 deal2809.45 is2809.68 with2810.41 the2810.64 sequencer.2810.89
2811.76 PARSONS2811.76 -2811.76 Right.2811.76 Exactly.2812.09
2813.26 MCEWAN2813.26 -2813.26 I2813.26 mean,2813.42 with2814.3 the2814.54 synthesizer,2815.34 sorry.2815.9
2815.9 PARSONS2815.9 -2815.9 Right,2816.22 because2816.38 it2816.94 trickles2817.18 down.2817.58
2818.46 MOLDES2818.46 -2818.46 Yeah.2818.46
2819.26 PARSONS2819.26 -2819.26 But2821.02 your2821.26 call.2821.58
2822.62 MOLDES2822.62 -2822.62 So2822.62 do2823.74 you2823.98 need2824.14 to2824.38 move2825.26 for2825.66 approval,2826.61 acceptance,2827.41 or?2828.14
2828.61 PARSONS2828.61 -2828.61 No.2828.61 So2829.09 some2829.41 amendments2830.61 we2830.86 do2831.09 wanna2831.34 have2831.66 go2831.89 to2832.05 the2832.14 board2832.3 of2832.53 health2833.74 but,2833.97 usually,2833.97 those2834.38 are,2834.53 like,2834.78 a2835.18 big2835.34 change2835.66 to2835.89 the2836.05 permit.2836.22 So,2837.49 like,2837.66 a2837.82 vivarium,2838.78 right?2839.37
2839.37 MOLDES2839.37 -2839.37 Yeah.2839.37
2839.53 PARSONS2839.53 -2839.53 We2839.53 just2839.69 added2839.77 a2840.17 vivarium.2840.25 That's2840.73 kind2840.89 of2841.05 a2841.13 big,2841.21 that's2841.61 a2841.85 big2842.01 change.2842.25 Something2842.97 like2843.29 this,2843.45 no.2843.77 You've2844.01 been2844.25 transparent2844.41 all2844.97 along.2845.21 You're2845.69 not2845.85 really2846.09 changing2846.33 your2846.73 research,2847.45 you're2847.69 not2847.69 really2847.93 changing2848.17 your2849.05 containment2850.01 level,2850.57 all2851.93 that2852.17 stuff.2852.41 This2853.13 is2853.37 just,2853.53 hey,2854.25 this2854.57 happened.2854.57 Not2855.98 our2856.22 fault.2856.46 This2856.94 is2857.18 what2857.26 we're2857.98 doing2858.22 to2858.46 prevent2858.55 future2858.94 things,2859.26 and2859.51 this2859.66 is2859.74 what2859.82 we're2860.07 gonna2860.14 do2860.46 if2860.86 in2861.26 the2861.42 unlikely2861.59 event2862.07 we2862.46 identify2862.7 a2863.26 risk2863.34 group2863.59 4.2863.9 And2865.9 so2866.22 the2866.63 board2866.78 of2867.03 health,2867.18 you2867.51 know,2867.66 they2867.98 don't,2868.07 they2868.98 trust2869.3 us2869.62 on2869.78 something2869.94 like2870.26 this.2870.42
2871.22 MOLDES2871.22 -2871.22 Okay.2871.22 Sounds2871.62 good.2871.86 So2872.5 do2873.06 we2873.3 need2874.34 written2874.74 approval2875.06 to2875.94 restart2879.06 work,2880.66 or?2881.06
2881.06 PARSONS2881.06 -2881.06 No.2881.61 Yeah.2881.93 You2882.09 can2882.24 restart2882.48 work.2883.13 If2883.45 you2883.68 could2883.76 upload2885.53 the2886.01 document2886.16 that2886.57 Mia2886.72 asked.2886.97 Yeah.2889.13 I2889.53 know,2889.93 and,2890.16 you2891.05 know,2891.28 get2891.53 back2891.76 to2891.93 it.2892.09
2894.01 MOLDES2894.01 -2894.01 Awesome.2894.01 Thank2894.01 you2894.24 very2894.48 much.2894.8
SHOW NON-ESSENTIAL DIALOGUE
2904.24 PARSONS2904.24 -2904.24 Okay.2904.24 Up2905.68 next,2905.92 we2906.32 have2906.48 additional2906.64 business.2907.12 So2907.52 is2908.97 there2909.21 any2909.3 additional2909.69 business2910.09 for2910.89 the2911.05 committee?2911.21
2915.45 MCEWAN2915.45 -2915.45 I2915.45 mean,2915.61 can2916.01 we2916.26 talk2916.57 about2916.89 screening2917.3 DNA2918.34 sequences?2918.82
2920.09 PARSONS2920.09 -2920.09 Sure.2920.09 I2921.38 mean,2921.53 I've2921.86 never2922.49 understood2922.82 the2924.28 difference2924.6 between2925 62925.32 and2925.64 7.2925.72 So2926.28 72926.52 is2926.76 items2927 that2927.24 cannot2927.48 be2927.8 anticipated2927.96 before2928.6 the2928.92 meeting,2930.68 so2930.92 this2930.92 falls2931.96 like,2932.44 maybe2933 this2933.24 is2933.48 6.5,2933.64 Deb.2934.92 Like,2935.4 didn't2937.41 say2937.73 it2937.86 come2937.97 before,2938.14 but2938.69 it's2938.86 come2939.09 since2939.34 the2939.57 meeting.2939.73 But,2940.05 yes,2940.3 by2941.09 all2941.26 means.2941.41
2942.78 MCEWAN2942.78 -2942.78 I2942.78 mean,2942.93 I2943.26 think2944.38 that2944.61 this2944.78 is2945.01 a,2945.17 like,2946.05 a2946.38 perfect2946.53 example2947.17 of2947.82 you2948.21 don't2949.36 anticipate2949.6 any2950.4 issues2950.72 with2951.44 the2951.76 sequences2952 you're2952.48 using2952.72 because2953.12 they're2953.52 from2954.48 a2954.8 paper,2954.96 you2956.08 know,2956.24 etcetera.2957.68 And2957.92 that2957.92 this2958.16 was2958.4 flagged2958.72 by2959.36 a2960.56 third2960.96 party2961.44 is2962.08 sort2962.32 of2962.56 fortuitous2963.28 for2964.26 them.2964.41 You2964.53 know,2964.65 if2964.73 they2964.97 hadn't2965.13 deposited2965.45 into2965.93 Addgene,2966.26 they2967.53 would2967.69 have2967.86 kept2968.01 using2968.26 it.2968.57 And2968.82 so2969.3 I2970.41 think2970.65 that2970.97 this2972.26 meeting,2972.65 you2973.93 know,2974.01 this2974.26 committee,2974.41 and2975.05 when2975.38 reviewing2975.61 permits2976.17 is2976.73 a2976.89 good2977.05 time2977.3 to2977.93 flag2978.49 this2979.69 for2980.57 companies,2981.61 right?2981.93 Like,2981.93 if2982.17 you2982.41 are2982.57 synthesizing2983.05 your2983.69 own2983.77 DNA2984.01 and2984.49 you're2984.65 not2984.89 just2985.05 buying2985.37 kits2985.69 from2986.01 a2986.81 company2986.97 that2987.45 does2987.69 screening,2987.93 you2989.05 should2989.21 insert2989.53 a2991.85 step2992.01 where2992.33 you2992.57 run2992.73 it2992.97 through2993.13 SecurDNA2994.2 or2994.99 another2995.39 software2996.2 program2996.76 as2999.47 a2999.88 confirmation.3000.11 I3001.39 don't3001.56 know3001.88 that3002.11 that3002.28 should3002.43 go3002.68 in3002.84 the3002.91 regulation,3002.99 but,3003.47 like,3003.72 we3003.88 do3004.04 provide3004.52 guidance3005.32 that's3005.88 not3006.11 always3006.68 directly3006.99 in3007.39 the3007.56 regulation.3007.72 And3008.36 this3008.52 seems3008.84 like3009.32 something3010.01 that3010.41 I3011.77 would3011.93 have3012.17 never3012.25 thought3012.49 of.3012.73 I3013.77 can't3013.93 be3014.25 the3014.49 only3014.57 person.3014.89
3016.57 PARSONS3016.57 -3016.57 No.3016.57 I3016.89 mean,3016.97 I3017.21 fully3017.29 agree.3017.61 And3017.85 the3018.01 fact3018.09 that3018.25 this3018.49 paper3018.65 is3018.89 five3019.05 years3019.29 old,3019.61 you3021.45 know,3021.61 says3021.85 a3022.09 lot,3022.73 right?3024.61 I3024.61 mean,3024.78 I3024.93 completely3025.02 agree3025.49 about,3027.26 and3029.34 I3029.57 agree3029.74 with3029.89 your3030.14 confusion3030.3 too3030.7 in3030.93 the3031.09 sense3031.26 of,3031.49 like,3031.57 is3031.74 this3031.97 something3033.57 we3033.89 regulate,3034.05 or3034.45 is3034.7 this3034.86 something,3035.02 like,3035.41 we,3035.66 you3036.3 know,3036.45 advise3036.78 on?3037.26 How3038.53 do3038.7 we3038.86 bring3040.26 this3040.5 into3040.66 Watertown,3040.98 so3041.46 to3041.7 speak?3041.78
3045.78 MCEWAN3045.78 -3045.78 I3045.78 don't3045.94 have3046.18 an3046.34 answer.3046.5 And3047.06 I3047.22 don't3047.38 also3047.62 want3048.02 it3048.26 to3048.34 just3048.5 be3048.82 dependent3049.06 on3049.62 us3050.66 remembering3051.14 to3051.78 bring3051.94 this3052.18 up3052.5 if3052.74 we3052.9 happen3053.06 to3053.38 see3053.54 that3053.7 they're3053.86 synthesizing.3054.18
3056.88 LIEBERMAN3056.88 -3056.88 Sometimes3056.88 we3057.28 don't3057.43 know3057.76 because3058.15 the3058.64 link3058.8 doesn't3060.07 really3060.47 include3060.8 that3061.11 little3061.36 detail3061.67 from3062.15 any3062.39 of3062.55 these3062.71 companies.3062.88 I3063.19 mean,3063.36 that's3063.51 sort3063.67 of3063.91 Cultivarium's,3063.99 like,3064.8 thing.3065.19 You3065.99 know,3066.15 that's,3066.32 like,3066.47 what3066.64 their3066.8 company3067.28 is3067.59 doing3067.76 versus,3068.15 you3069.27 know,3069.43 synthesizing3069.51 DNA3070.23 for,3070.63 you3070.87 know,3070.95 completely3071.19 different3071.83 reason.3074.87 But3075.67 I3075.91 think3075.99 it's3076.31 the3076.63 companies3076.79 with,3077.11 like,3077.27 their3077.43 really3077.59 large3077.91 libraries3078.23 of3078.63 bacterial3078.79 species3079.35 that3079.75 this3079.91 is3080.15 gonna3080.31 apply3080.63 to.3080.95 We3081.75 don't3081.91 have3082.15 that3082.39 many3082.55 here,3085.56 certainly,3085.95 any3085.95 of3087.47 the3087.64 contract3087.88 manufacturing3088.43 places3089.24 or,3089.72 you3091.32 know,3091.47 where3091.72 there's3091.95 potential.3092.28
3094.52 MCEWAN3094.52 -3094.52 I3094.52 don't3094.68 think3094.91 that3095.16 this,3095.56 I3095.88 mean,3095.95 that3096.2 is3096.36 an3097.79 example3098.03 of3098.43 a3098.59 company3098.75 that3098.99 have3099.15 this3099.31 issue,3099.47 but3099.71 you3099.87 could3100.03 just3100.19 work3100.43 with3100.67 one3101.15 strain3101.55 but3101.55 be3101.71 trying3101.87 different3102.19 expression3102.51 vectors3102.99 that3103.31 you're3103.47 making3103.63 and3104.27 have3104.43 the3104.67 same3104.75 issue.3104.91
3106.19 LIEBERMAN3106.19 -3106.19 Yeah.3106.19
3110.97 MCEWAN3110.97 -3110.97 I3110.97 mean,3111.14 what3111.3 we3111.45 need3111.7 is3111.93 a3112.26 more3112.41 comprehensive3112.66 system3113.3 where3113.7 all3113.93 sequencers3114.18 just3114.74 have3114.97 this,3115.22 but3115.93 we're3116.09 not3116.34 at3116.74 that3116.74 point.3117.06
3118.89 PARSONS-3118.89 Right.3118.89 So3119.22 I3119.45 was3119.54 thinking,3119.7 like,3120.18 the3120.34 opposite3120.58 in3121.38 terms3121.61 of,3121.93 like,3125.04 is3125.44 there3125.68 a3125.92 question3126 we3126.4 can3126.56 pose,3129.92 but3130.64 it's3130.8 more3130.96 nebula3131.28 in3131.76 the3131.92 sense3132 of,3132.24 like,3132.4 how3133.52 do3133.68 you3133.84 know3134 you3135.28 will3135.44 not3135.76 be3135.92 expressing3136.08 RG3136.8 33137.68 or3137.92 4,3138.24 you3140.61 know,3140.78 something3141.57 like3141.89 that.3142.21
3143.41 MCEWAN3143.41 -3143.41 Well,3143.41 if3144.05 you're3144.3 using3144.53 I3145.06 mean,3145.18 if3145.34 you're3145.41 just3146.05 purchasing3146.3 all3146.78 your3146.86 plasmids,3147.09 which3147.57 is3147.82 probably3147.97 the3148.45 majority3148.61 of3149.01 companies3149.18 then3150.53 this3150.93 shouldn't3151.26 be3151.66 a3151.89 concern.3151.97
3152.78 PARSONS3152.78 -3152.78 Right.3152.78 But3155.92 this3156.16 is3156.32 where3156.4 I3156.56 get3156.64 confused3156.8 because3157.12 I'm3157.28 not3157.44 a3157.6 microbiologist,3158.64 so3160.32 when3160.32 she3160.64 said3161.12 that3162.08 they3162.56 notified3162.96 the3163.68 distributor,3163.92 what3165.28 were3165.44 they,3165.68 if3166.08 they're3166.32 like,3167.12 what3167.68 did,3167.92 to3168.82 me3169.07 that3169.22 implied3169.46 they3169.78 bought3170.03 a3170.26 product3170.34 that3170.74 wasn't3170.91 what3171.39 they3171.55 expected3172.34 it3172.74 to3172.98 be.3173.07
3174.18 MCEWAN3174.18 -3174.18 I3174.18 thought3174.34 Addgene3174.66 notified3175.07 them.3175.63
3175.95 LIEBERMAN3176.26 -3176.26 Addgene3176.26 notified3176.26 them.3176.82
3177.46 PARSONS3177.46 -3177.46 It3177.78 was3177.86 the3178.11 other3178.18 way3178.34 around?3178.59
3179.39 MCEWAN3179.39 -3179.39 Right.3179.39
3181.3 PARSONS3181.3 -3181.3 Gotcha.3181.3 Okay.3181.95 I3182.91 missed3183.07 that.3183.39 Okay.3187.03 That's3187.27 different.3187.51 Yeah.3187.91 That's3188.23 very3188.47 different.3188.79 And3194.47 so,3194.79 Deb,3195.59 just3195.91 my3196.15 own3196.39 knowledge3196.79 or3197.51 understanding,3197.75 what3198.99 made3199.16 you3199.39 think3199.55 of3199.8 Twist?3199.95
3201.64 MCEWAN3201.64 -3201.64 Because3201.64 I3202.36 took3202.76 a3202.91 little3203.07 screenshot3203.55 of3204.2 their3204.43 sequence3204.68 of3204.99 events,3205.16 and3205.55 it3205.72 said,3205.88 you3206.11 know,3206.2 they3206.68 put3207.16 the3207.32 request3207.47 into3207.95 Twist3208.2 Biosciences,3208.52 and3209.64 Twist3210.11 just3210.59 created3210.84 it3211.24 without3211.39 flagging3211.72 it.3212.11
3212.64 PARSONS3212.64 -3212.64 Okay.3212.64
3212.96 LIEBERMAN3212.96 -3212.96 Oh,3212.96 no.3213.12 They3213.36 said3213.52 that3213.68 they3213.84 informed3214.08 Addgene.3214.64 I3215.12 just3215.2 want3215.36 to3215.52 pull3215.76 that3216.16 back3216.32 up.3216.56
3218.4 PARSONS3218.4 -3218.4 That's3218.4 where3218.64 I'm3219.44 confused3219.6 because3220 I3220.24 think3220.32 they3220.72 were,3221.2 they3221.6 being3221.76 Cultivarum,3224.4 were3224.64 the3224.64 ones3224.72 who3224.96 figured3225.36 out3225.76 something3225.92 was3226.24 up.3226.48
3229.66 MCEWAN3229.66 -3229.66 Oh,3229.66 then3230.86 how3231.09 did3231.26 they3231.41 identify3232.3 the3232.7 sequences?3232.86
3233.57 LIEBERMAN3233.57 -3233.57 I3233.57 think3233.66 they3233.89 ran3234.05 it3234.22 through3234.38 SecureDNA.3234.93 I3235.97 think3236.05 they3236.3 just3236.45 were3236.93 doing3237.18 that3237.41 probably3237.57 for3237.89 something3238.14 else3238.38 and3238.61 it3238.78 came3238.93 up.3239.18
3239.82 PARSONS3239.82 -3239.82 Right.3239.82
3240.84 MCEWAN3240.84 -3240.84 Oh.3240.84
3241.72 PARSONS3241.72 -3241.72 So,3242.68 Deb,3242.92 that's3243.16 where3243.4 I3243.64 was3243.8 going3243.96 with3244.28 the3244.44 question3244.6 of,3245.16 how3245.48 do3245.8 you3245.88 know3246.04 if3246.92 your3247.08 material3247.32 is3247.72 RG,3248.04 not3249.72 source,3249.96 but3250.28 you3250.52 know3250.6 what3250.68 I3250.84 mean,3251.32 like,3252.2 contains3252.2 fragments3252.76 of3253.24 the,3254.04 you3254.6 know?3254.84 Ralph,3257.49 you3257.8 know3257.89 where3258.05 I'm3258.13 going3258.2 with3258.36 this3258.45 because3258.53 I3258.64 don't3258.76 know3258.93 how3259.09 to3259.24 say3259.32 it3259.64 correctly.3259.8
3260.36 MELE3260.36 -3260.36 Yeah.3260.36 That's3260.61 kind3260.84 of3261.09 what3261.09 I3261.32 asked3261.8 for3262.13 my3262.28 follow-up,3262.84 but3263.32 I3263.72 don't3264.05 know3264.28 the3264.45 right3264.61 terms3264.84 to3265.24 ask3265.32 for3265.57 that.3266.13
3266.13 MCEWAN3267.32 -3267.32 Can3267.32 we3267.8 ask3268.13 Addgene?3268.53 I3269.09 mean,3269.24 they're3269.49 a3269.57 Watertown3269.72 company.3270.2
3271.07 PARSONS3271.07 -3271.07 That's3271.07 what3271.23 I3271.39 thought,3271.87 right?3272.11 I3272.11 feel3272.27 like3272.43 this3272.67 is,3272.83 like,3272.91 a3273.15 Watertown3273.31 problem.3274.03
3275.31 MCEWAN3275.31 -3275.31 No.3275.31 I3275.55 mean,3275.71 this3275.87 is3276.11 a3276.23
3276.23 LIEBERMAN3276.23 -3276.23 Twist3276.43 is3276.75 where3276.83 they3277.07 order3277.31 them3277.55 first.3277.79
3278.19 MCEWAN3278.19 -3278.19 And3278.19 they're3278.43 California.3279.23
3280.35 PARSONS3280.35 -3280.35 Oh,3280.35 Twist3280.51 is3280.83 California?3280.99
3282.11 MCEWAN3282.11 -3282.11 At3282.11 least3282.27 my3282.59 googling3282.83 said3283.31 it3283.55 was3283.71 California,3283.87 but3285.04 they3285.43 might3285.59 have,3285.84 I'm3286.16 assuming3286.32 they3286.72 have3286.8 closer3287.04 locations.3287.43
3288.39 PARSONS3288.39 -3288.39 Right.3288.39 Because3288.64 I3288.88 had,3289.28 for3289.52 some3289.76 reason3289.91 Twist3290.24 sparked3291.11 a3291.68 memory3291.91 of3292.39 a3292.72 us3293.43 reviewing3293.99 a3294.56 Twist,3294.72 application.3296.47 No?3297.43 Okay.3298.08
3301.12 LIEBERMAN3301.12 -3301.12 And3301.12 they3301.28 were3301.44 synthesized3301.68 all3302.16 the3302.32 way3302.4 back3302.56 in3302.72 December3302.88 2022.3304.72
3306.4 PARSONS3306.4 -3306.4 Okay.3306.4 But3308.96 Addgene3309.28 is3309.76 Watertown.3310.56
3316.69 LIEBERMAN3316.69 -3316.69 Oh,3316.69 no,3317.18 you're3317.34 right.3317.34 Addgene3317.66 did3318.14 flag3318.61 them.3318.93 They3320.14 deposited3320.53 them,3322.05 sorry,3322.3 I'm3322.3 reading3322.53 the3322.78 more3322.93 detailed3323.18 thing.3323.57 They3325.49 gave3325.82 them3326.05 to3326.21 Addgene.3331.27 And3331.27 then3333.03 when3333.35 they,3333.67 I3334.55 think3334.63 they3335.67 were3335.83 trying3336.07 to3336.31 make3336.39 them3336.55 available3336.71 to3337.19 order3337.35 and3337.67 then3337.75 Addgene3337.99 flagged3339.35 them.3339.83
3340.63 MCEWAN3340.63 -3340.63 Yeah.3340.63
3342.49 PARSONS3342.49 -3342.49 Well,3342.49 it's3342.57 nice3342.8 to3342.89 see3343.05 Watertown3343.36 companies3343.77 working3344.16 with3344.49 Watertown3344.64 companies,3345.13 on3345.93 a3346.16 side3346.24 note3346.49 to3346.72 be3346.89 positive3347.13 and3347.45 optimistic3348.32 about3348.97 this.3349.2 Okay.3354.32
3355.91 LIEBERMAN3355.91 -3355.91 I3355.91 mean,3356.07 I3356.31 think,3356.47 like,3356.79 if3357.11 it's3357.35 partial3357.67 sequences,3363.75 because,3363.75 theoretically,3364.07 it's3364.63 not3364.87 gonna3365.03 replicate,3366.23 you3366.47 know.3366.47
3366.47 PARSONS3366.47 -3366.47 Well,3366.47 so3366.63 that's3366.79 the3366.95 other3367.03 thing.3367.27 I3367.43 didn't3367.59 wanna3367.75 be3368.07 dismissive,3368.23 but3368.71 I3368.87 was3368.95 like,3369.11 this3369.27 is3369.43 was,3370.03 what3370.28 was3370.51 it?3370.67 6%3370.91 of3371.8 the3372.36 sequence,3374.03 right,3374.28 and3374.28 it3374.28 was3374.36 one3374.67 of3374.91 five3375.07 of3375.47 the3375.71 protein.3375.95 So3376.36 I3376.59 was3376.76 just3376.91 kind3377.16 of3377.39 like,3377.39 okay,3379.88 so3380.03 there's3380.03 a3380.43 match3380.67 here,3381.07 but3382.36 what's3382.6 the3382.92 risk?3383.16
3384.12 MCEWAN3384.12 -3384.12 I3384.12 mean,3384.6 I3384.92 don't,3385.08 from3385.48 my3385.72 take,3385.96 it's3386.2 not3386.36 that3386.6 there3386.68 was3386.84 a3387 risk.3387.16 It3387.48 was3387.56 just3387.8 that3388.04 they3388.36 were3388.52 working3388.68 with3389 something3389.16 they3389.4 didn't3389.56 know3390.28 they3390.52 were3390.68 working3390.92 with.3391.24
3391.56 PARSONS3391.56 -3391.56 Okay.3391.56
3391.96 MCEWAN3391.96 -3391.96 And3392.2 that's3392.36 what3392.6 the3392.84 concern3393.64 is.3394.04
3394.6 PARSONS3394.6 -3394.6 Okay.3394.6 Yeah.3395 So3395.32 they're3395.48 just3395.72 being3395.96 upfront3396.7 and3397.11 transparent3398.14 but3398.63 not3399.59 doing3399.83 work3400.14 that's3400.47 concerning3402.22 in3402.79 the3402.95 sense3403.03 of,3403.34 okay.3403.83
3404.22 MCEWAN3404.7 -3404.7 Yeah.3404.7
3408.7 PARSONS3408.7 -3408.7 So3408.7 a3408.87 question3409.03 to3409.43 Mia3409.59 and3409.91 Deb3410.14 is,3410.63 and3412.49 this3412.65 is3412.89 a,3412.97 you3413.53 know,3413.77 your3414.01 personal3414.25 opinion,3414.81 is3416.17 there,3416.41 like,3416.57 a3416.89 percentage3417.13 of3418.01 a3418.17 sequence3418.33 that3418.73 you3418.97 would3419.13 then3419.29 feel3419.61 uncomfortable?3420.01 Like,3420.57 this3420.81 was,3421.85 where3422.25 was3422.41 it,3422.81 like,3423.61 53423.61 out3424.73 of,3426.86 no,3427.11 553427.11 out3427.74 of3427.91 5623428.7 or3429.59 something3429.83 like3430.14 that?3430.95
3431.03 MCEWAN3431.03 -3431.03 I3431.03 mean,3431.03 there's3431.34 not3431.59 a3431.74 blanket3431.91 statement3432.79 you3433.03 can3433.03 make.3433.03
3433.03 LIEBERMAN3433.03 -3433.03 Yeah.3433.03 It3433.03 depends3433.18 what3433.59 it's3433.74 encoding.3434.31
3435.03 MCEWAN3435.03 -3435.03 And3435.03 where3435.43 the3435.66 functional3435.74 domains3436.22 are3437.18 and,3437.83 there's3437.83 a3438.22 lot3438.31 to3438.55 it.3438.79
3439.66 PARSONS3439.66 -3439.66 Right.3439.66 So3439.91 it's3440.14 hyper3440.47 specific.3440.79
3441.86 LIEBERMAN3441.86 -3441.86 I3441.86 mean,3442.02 a3442.26 capsule,3442.62 if3443.14 it3443.3 was,3443.38 you3443.62 know,3444.58 lethal3444.9 toxin3445.46 from3446.02 anthrax,3447.38 I'd3447.94 be3448.18 like,3448.26 no,3448.74 you3448.98 shouldn't3448.98 be3449.22 working3449.38 with3449.7 that.3449.86 The3450.98 capsulin3451.3 antigen,3451.94 like,3452.5 okay.3452.82 Fine,3453.46 whatever.3455.41 But,3455.41 like,3455.66 some3455.97 of3456.3 the3456.38 other3456.54 toxin3456.78 genes,3457.26 it's3457.66 like,3457.74 no.3457.97 You3458.22 you3458.45 have3458.7 no3458.93 reason3459.09 to3459.41 be3459.57 working3459.74 with3460.05 that.3460.22
3460.78 PARSONS3460.78 -3460.78 Gotcha.3460.78 Okay.3461.34 So3461.82 it3461.97 truly3462.14 is3462.45 hyperspecific3462.86 to,3463.89 okay.3464.38 Alright.3465.49
3467.63 MCEWAN3467.63 -3467.63 But3467.63 I3467.79 think3467.95 that's3468.03 where3468.35 the3468.59 screening3468.75 software3469.23 is3469.55 helpful3469.71 because3470.11 it3471.87 doesn't3472.11 just3472.43 flag3472.83 sequence.3473.31 It3473.79 also3474.03 has3474.35 some,3474.59 you3475.47 know,3475.55 algorithms3476.35 behind3476.91 it3477.31 to3477.47 flag3478.35 risk3478.83 level3479.07 of3479.71 that3479.87 sequence.3480.11
3481.23 PARSONS3481.23 -3481.23 Okay.3481.23
3486.89 MCEWAN3486.89 -3486.89 So3487.44 this3488.16 is3488.32 not3488.48 something3488.72 that3489.13 this3489.61 committee3489.93 is3490.32 going3490.64 to3491.13 solve.3491.2 So3493.2 maybe3493.53 it's3493.84 enough3494.16 to3494.72 just3495.2 have3495.44 one3496.47 of3496.71 the3497.03 questions3497.19 be,3498.47 are3498.79 all3499.03 of3499.11 your3499.27 plasmids3499.51 from3500.07 a3500.47 company3500.63 like3501.03 Addgene?3501.27 And3501.75 if3501.99 not,3502.23 we3503.11 would3503.51 advise3503.83 running3504.47 it3504.79 through3505.03 a3505.75 software3505.99 before3507.27 synthesizing.3508.63
3510.55 PARSONS3510.55 -3510.55 Yeah.3510.55 I3510.71 mean,3510.95 that3511.03 seems3511.2 completely3511.51 reasonable3511.99 because3512.71 we're3513.03 saying3513.11 advised3513.51 and3513.84 we're3513.99 not3514.23 saying,3514.39 because3515.68 I3516.07 really3516.23 do3516.47 prefer3516.64 recommendations3517.76 based3518.55 off3518.8 of3519.11 real3519.36 life3519.68 experience3520.39 versus3520.95 hypothetical,3521.43 you3522.23 know,3522.47 things3522.71 could3523.03 go3523.28 wrong3523.43 but3524.22 they3524.46 never3524.62 have.3524.86 But3525.26 just3525.5 because3525.66 there's3525.9 a3526.14 1%3526.3 chance3526.78 that3527.02 it3527.18 could,3527.34 you3527.98 know,3528.06 I3528.22 don't3528.3 like3528.46 that,3528.7 especially3529.58 being3529.98 in3530.22 the3530.3 safety3530.38 profession.3531.74 But3532.46 this3532.62 is3532.78 real.3532.94 This3533.18 is3533.42
3533.82 MCEWAN3533.82 -3533.82 It's3533.82 a3533.82 very3533.82 easy3533.82 step.3534.06
3534.62 PARSONS3534.62 -3534.62 Yeah.3534.62 Exactly.3534.86
3535.9 MCEWAN3535.9 -3535.9 It3535.9 doesn't3536.06 even3536.3 cost3536.62 anything.3536.86
3537.72 PARSONS3537.72 -3537.72 Right.3537.72 It's3538.05 an3538.13 easy3538.36 step3538.68 and3539.09 we3539.49 have3539.72 reason3539.89 to3540.28 say,3540.45 we3541.72 have3541.97 real,3542.13 you3542.45 know,3542.61 experience3542.93 to3543.41 say3543.57 why3543.89 it's3544.36 a3544.61 good3544.68 idea.3544.84 So3545.64
3547.09 FOLEY3547.09 -3547.09 Okay.3547.09 I3547.72 got3547.89 to3548.28 ask3548.28 a3548.45 question3548.53 again.3549.01
3549.57 PARSONS3549.57 -3549.57 Yep.3549.57
3550.45 FOLEY3550.45 -3550.45 You3550.45 said,3550.61 are3551.32 all3551.57 your3551.72 plasmids3552.05 purchased3552.93 in3555.38 the?3555.38
3555.38 MCEWAN3555.38 -3555.38 I3556.58 mean,3556.74 I3556.9 don't3556.98 wanna3557.14 call3557.46 it3557.62 a3557.78 specific3557.94 company.3558.34 But,3558.74 like,3558.9 if3559.14 you3559.38 are3559.54 generating3559.78 your3560.5 own3560.82 plasmids3562.74 or3563.38 DNA3563.62 sequences,3564.1 then3565.88 you3566.51 should3566.76 give3566.99 them3567.16 a3567.39 screen.3567.55 If3567.8 you're3567.95 just3568.51 purchasing3568.76 everything3569.32 from3569.88 a3570.11 place3570.2 that's3570.43 already3570.59 done3570.91 the3571.07 screening,3571.24 then3571.8 it3571.95 wouldn't3572.11 be3572.36 necessary.3572.59
3596.76 FOLEY3596.76 -3596.76 Okay.3596.76 I3597.24 think.3597.39
SHOW NON-ESSENTIAL DIALOGUE
3610.64 FOLEY3610.64 -3610.64 Will3611.28 that3611.52 go3611.52 one3611.52 of3611.52 the3611.68 questions3611.76 on3612.24 the3612.48 new3612.64 application3612.96 for3614.8 renewals?3615.04
3617.28 LIEBERMAN3617.28 -3617.28 No.3617.28 It's3617.68 really3617.92 more3618.24 for3618.4 new3618.64 companies,3618.8 I3619.36 feel3619.52 like.3619.68 Next3621.93 month,3622.18 we3622.57 should3622.74 probably3622.97 talk3623.3 about3623.53 renewals.3626.34
3629.05 PARSONS3629.05 -3629.05 Certainly.3629.05 Yeah.3629.78 October.3630.18 Wow.3630.97
3632.09 FOLEY3632.09 -3632.09 Maybe3632.09 we3632.49 should3632.66 do3632.89 a3633.05 Zoom3633.22 with3633.45 Abby3633.7 because3633.93 she's3634.26 the3634.41 only3634.57 one3634.82 that3634.97 can3635.22 edit.3635.53
3639.51 LIEBERMAN3639.51 -3639.51 Okay.3639.51 If3639.51 we3639.75 can3639.83 have,3640.07 like,3640.23 a3640.39 live3640.63 walk3640.95 through3641.27 of3641.51 the3642.39 questions3642.63 being3643.19 asked3643.43 for3643.67 the3643.83 renewables,3643.99 I3644.47 think3644.55 that3644.79 would3644.95 be3645.11 helpful3645.19 to3645.67 make3645.83 sure3645.99 that3646.31 we3646.47 all3646.63 look3646.87 at3647.03 what's3647.99 being3648.39 asked3648.71 and3649.35 are3649.51 satisfied3651.3 with3651.94 the3652.03 layout3652.18 of3652.42 how3652.59 it3652.74 appears.3652.9
3654.11 FOLEY3654.11 -3654.11 Exactly.3654.11 Yes.3656.98 So3657.46 a3658.11 live3658.26 Zoom3658.66 would3658.9 be,3659.14 like,3660.26 really3660.82 good3661.14 that3661.7 we3661.86 can,3662.03 this3662.82 stuff.3662.98 But3663.39
SHOW NON-ESSENTIAL DIALOGUE
FOLEY3667.29 -3667.29 Oh,3667.29 that's3667.45 just3667.77 my3667.93 suggestion3668.17 is,3668.73 like,3669.05 doing3669.29 it3669.53 in3669.61 a3669.61 live3669.77 Zoom3670.01 so3670.33 she3670.57 can3670.73 edit3670.97 while3671.37
3672.17 LIEBERMAN3672.17 -3672.17 Yep.3672.17
3674.09 FOLEY3674.09 -3674.09 Because3674.09 I3674.57 know3674.65 there's3674.97 plenty3675.37 of3675.69 duplicates3675.85 on3676.41 this3676.57 thing.3676.73 Okay.3678.65
3683.36 PARSONS3683.36 -3683.36 There3683.36 are,3687.84 yes.3687.84 Okay.3687.84 So,3693.43 for3693.43 the3693.67 October3693.91 agenda3694.47 already3694.87 we3695.27 know3695.43 to3695.75 discuss3695.91 renewals.3696.63 See3701.27 if3701.43 we3701.51 can3701.59 get3701.83 this3701.99 live3704.39 Zoom3704.79 with3705.35 Abby3705.59 to3706.15 do3706.31 a3706.47 walk3706.55 through.3706.79 The3708.43 sooner3708.82 the3708.82 better.3709.07 Okay,3713.55 that's3713.86 good.3713.86 That's3714.03 definitely3714.18 additional3714.59 business.3714.99 Anything3717.14 else?3717.47 Any3723.82 items3724.06 that3724.46 cannot3724.62 be3724.86 anticipated3725.18 before3725.9 the3726.22 meeting?3726.38 Okay.3732.14 Future3735.68 meetings,3736.95 okay.3737.52 So3737.52 it3737.84 has3746.07 been3746.24 brought3746.24 to3746.47 my3746.64 attention3746.88 that3747.59 October3748.81 3rd3749.21 is3749.61 not3749.85 a3750.01 good3750.09 day3750.25 to3750.57 have3750.65 a3750.81 meeting,3750.97 so3751.85 that3752.17 means3752.57 October3753.05 10th.3753.53 Ralph,3756.09 are3756.49 you3756.65 available3756.89 on3757.61 October3757.85 10th?3758.41
3761.99 MELE3761.99 -3761.99 I3761.99 will3762.39 not3762.64 be3762.88 available3763.03 October3763.51 10th.3763.84
3764.64 PARSONS3764.64 -3764.64 Okay.3764.64 Deb,3765.51 will3765.84 you3765.99 be3766.16 available3766.32 October3766.8 10th?3767.11
3767.84 MCEWAN3767.84 -3767.84 Yes.3767.84
3769.11 PARSONS3769.11 -3769.11 Mia,3769.11 will3769.51 you3769.76 be3769.91 available3770.24 October3770.72 10th?3771.2
3771.91 LIEBERMAN3771.91 -3771.91 Yep.3771.91
3772.95 PARSONS3772.95 -3772.95 Okay.3772.95 I3774.8 will3774.95 email3775.2 Tim3775.68 right3776.58 now3778.34 to3780.1 confirm3780.26 if3781.46 he's3781.62 available.3781.94 So3782.42 let's3782.58 just3782.74 say3782.98 for3783.22 now,3783.38 we're3783.78 tentatively3784.02 scheduled3786.66 for3787.06 the3787.3 10th.3787.3 The3789.43 third3789.59 is3789.84 definitely3789.91 off3790.47 the3790.64 books,3790.8 so3791.84 we'll3792.07 have3792.32 to3792.47 be3792.64 creative3792.88 if3793.28 Tim3793.59 can't3794.07 make3794.32 the3794.56 10th.3794.72 I3796.39 just3796.56 don't3796.8 like3796.95 scheduling3798.07 a3798.64 meeting3798.72 where3799.04 we3799.2 know3799.36 that3799.59 definitely3801.77 two3802.17 people3802.41 will3802.65 not3802.89 be3803.05 available.3803.29 So3804.73 let3807.37 me3807.53 just3807.69 do3811.05 this3811.21 right3811.45 now3811.61 because3811.77 I3812.01 will3812.09 forget3812.33 because3812.73 it's3812.89 been3813.45 that3813.61 kind3813.85 of3814.17 week.3814.17 Alright.3817.78 I3818.11 have3818.18 that3818.43 up.3818.59 I3818.74 will3818.91 email3819.14 Tim3819.46 when3819.86 this3820.03 meeting3820.26 is3820.51 over.3820.74 And3822.26 then,3822.51 Maureen,3822.74 I3823.22 will3823.39 let3823.55 you3823.78 know,3823.94 when3826.26 I3826.51 hear3826.59 back3826.74 from3826.91 Tim,3827.14 one3829.58 way3829.74 or3829.9 the3829.98 other,3830.14 and3830.46 then3830.54 we'll3830.7 have3830.94 to3831.1 fig,3831.18 if3831.42 he's3831.58 not3831.82 available,3832.06 then3832.46 we'll3833.1 have3833.26 to3833.34 figure3833.5 out3833.66 what3833.82 we're3833.98 gonna3834.06 do.3834.38 Alright.3840.86 Well,3841.26 I3841.42 think3841.58 that3841.82 brings3841.98 us3842.22 to3842.46 the3842.62 end.3842.78 So3843.8 thank3844.36 you3844.61 everyone,3844.93 for3846.05 your3846.2 time,3846.93 really3847.41 appreciate3847.41 it.3847.72 I3849.41 hope3849.57 everyone3850.05 survives3850.45 the3850.93 first3851.89 week3852.13 of3852.36 September.3852.53 It's3853.09 usually3853.32 a3853.64 crazy3853.8 one.3854.13 Welcome3855.49 back,3855.89 Deb.3856.13 And,3857.24 you'll3859 hear3859.32 from3859.56 us3859.72 shortly,3860.04 I3861.48 assume3861.64 shortly,3861.96 I3862.36 assume3862.44 Tim3862.76 will3863 write3863.16 back3863.4 to3863.56 me3863.72 quickly,3863.88 about3865.08 the3865.64 date3865.8 for3866.04 the3866.2 October3866.44 meeting.3868.52 And3868.52 with3868.76 that,3868.92 at3870.51 8:0:63870.82 PM3871.7 on3872.18 September3872.51 5th,3872.98 the3873.55 Watertown3874.11 Biosafety3874.59 Committee3875.22 meeting3875.7 is3876.03 adjourned.3876.26 Thank3876.74 you,3876.91 everyone.3877.14