Watertown Biosafety Committee
Thursday August 6, 2026
The order of items in transcripts is the chronological order in which they were taken up. Some Agenda items may have been skipped.
BRAD14.89 PARSONS14.89 -14.89 BIOSAFETY14.89 COMMITTEE14.89 CHAIR14.89 -14.89 Thank14.89 you15.13 everyone15.38 for15.86 your16.02 patience.16.26 It's18.02 the18.34 summertime,18.5 and19.05 we're19.3 moving19.54 in19.77 summertime20.02 pace.20.65 Our24.54 consultant,24.78 how25.66 dare25.9 she,26.22 is26.78 in27.02 Spain,27.26 and29.02 she's29.26 the29.58 host.29.82 And30.7 we31.1 have31.26 this31.42 webinar31.66 format32.14 due32.62 to32.78 Zoom32.94 bombing.33.18 And33.66 so,33.9 at35.66 06:58,35.9 I36.62 decided36.78 to37.18 try37.34 to37.5 fix37.66 it.37.9 So38.37 my38.61 apologies.38.84 Thank39.41 you39.57 for39.73 your39.89 patience.40.05 And42.05 welcome42.2 to42.77 the43.48 August44.61 202645.45 version46.29 of46.61 the46.77 Watertown46.93 Biosafety47.33 Committee47.89 meeting.48.2 So,48.52 Maureen,48.69 I'm49.09 gonna49.33 call49.73 this50.77 meeting,51.01 to52.43 order52.75 at53.47 07:05PM.53.71 And61.15 since61.31 we're61.63 not61.87 all62.11 here,62.27 and63.39 we63.55 should63.79 do63.95 a64.11 roll64.27 call64.51 anyway.64.67 Maureen,65.23 can65.55 we65.71 do65.87 a66.03 quick66.19 attendance?66.51 68.48 MAUREEN68.48 FOLEY68.48 -68.48 CITY68.48 OF68.48 WATERTOWN68.48 -68.48 Okay.68.48
SHOW NON-ESSENTIAL DIALOGUE
69.61 Deb69.61 McEwen?69.92 71.28 SPEAKER371.28 -71.28 He's71.28 present.71.53 74.56 SPEAKER274.56 -74.56 Tim74.56 McGuire?75.05 75.77 SPEAKER475.77 -75.77 Present.75.77 77.84 SPEAKER277.84 -77.84 Ralph77.84 Milly?78.25 79.13 SPEAKER379.13 -79.13 Present.79.13 81.16 SPEAKER281.16 -81.16 And,81.16 Brad82.52 Parsons83.8 84.76 SPEAKER584.76 -84.76 present84.76 grandfather84.92 also85.8 testified.86.04 86.68 SPEAKER86.68 -86.68 Thank86.68 you86.92 this87.64 morning.87.88 188.28 month.88.52 PARSONS88.92 -88.92 Okay.88.92 All90.76 right.90.92 So91.16 first,91.32 up91.64 on91.8 the91.88 agenda92.04 is92.44 the92.68 acceptance.92.76 Of94.72 the94.97 minutes95.13 as95.53 submitted95.77 by96.33 Maureen,96.65 for97.69 the98 07/08/202698.25 meeting.100.08 Does101.36 anyone101.69 from102.33 the102.81 committee102.97 have103.44 any103.77 questions104.17 comments104.56 or104.97 edits?105.2 No.109.4 All109.72 right.109.8 Seeing110.12 none.110.36 We'll110.6 just110.76 do110.92 a111.08 quick111.16 vote.111.4 All112.28 those112.52 in112.84 favor113.08 of113.32 accepting113.56 the113.88 minutes114.04 as114.36 submitted114.52 for114.92 July115.08 2026.115.72 Please116.36 raise116.76 your117 hand117.16 or117.4 say117.56 yes.117.8 Alright,119.26 Maureen,119.58 for119.9 the120.06 record,120.14 the120.62 four120.86 attending121.26 members121.66 all122.06 voted122.22 yes.122.53 And124.69 again,124.94 thank125.26 you125.42 so125.58 much125.73 for125.98 all126.14 your126.3 work.126.45 We126.78 really,126.94 really,127.34 truly127.66 appreciate128.14 it.128.53 Alright.130.69 This133.2 is133.32 the133.44 time133.68 for133.92 public134.16 comment.134.48 I134.88 know135.04 everyone135.28 is135.68 here,135.92 not137.52 as137.84 a137.92 member138 of138.32 the138.4 public,138.56 but138.88 as139.12 a139.28 member139.36 of,139.76 either141.44 FTGEN141.84 or142.48 Cellens.142.72 So143.2 but143.6 I143.68 still143.84 have144.08 to144.16 do144.32 it.144.48 Is145.44 there145.52 anyone145.76 here146 from146.24 the146.4 public146.48 wishing146.8 to147.12 make147.2 a147.36 public147.44 comment?147.92 Okay.151.47 Seeing152.36 none.152.68 Next154.92 item,155.24 number155.64 four,155.88 permits156.44 to156.92 be157 reviewed.157.16 So158.12 we160.36 have,160.92 let161.91 me162.07 pull162.23 up162.39 my162.63 notes.162.79 Cellens163.51 Incorporated.164.15 Who167.51 here167.83 is168.07 from168.23 Cellens?168.71 170.31 NICOLE170.31 BILLINGS170.31 -170.31 CELLENS170.31 INC.170.31 -170.31 I170.31 am.170.55 171.35 PARSONS171.35 -171.35 Hi,171.35 Nicole.171.67 Welcome.172.15 172.71 BILLINGS172.71 -172.71 Thank172.71 you.172.95 174.41 PARSONS174.41 -174.41 Do174.41 you,174.49 do176 you176.17 have176.25 a176.49 deck176.56 or176.81 are177.04 you177.13 here,177.28 speaking178.09 only?178.49 179.21 BILLINGS179.21 -179.21 I'm179.21 just179.37 here179.6 speaking179.84 only.180.17 181.13 PARSONS181.13 -181.13 Okay.181.13 Great.181.44 So182.49 welcome.184 And184.72 so185.21 what185.44 we185.6 normally185.76 have186.25 people186.41 do186.81 is,187.28 just187.93 a188.17 very188.25 brief188.56 description,189.36 of190.43 your190.96 science,191.2 and191.76 then192 we192.4 open192.64 up193.12 the,193.68 floor196 to196.24 questions,196.4 for197.36 the197.6 committee.197.68 BILLINGS198.88 -198.88 Absolutely.198.88 Great.199.6 So,200 my200.96 name201.12 is201.28 Nicole201.44 Billings.201.76 I'm202.24 here202.48 on202.72 behalf202.8 of203.54 Cellens.203.63 So204.59 we204.82 are204.99 a205.22 cancer205.31 diagnostic205.71 company.206.43 We're207.63 currently207.87 based208.34 in,208.75 Charlestown,209.39 but209.94 we're210.19 moving210.34 to210.67 Watertown210.82 in211.54 the,211.78 Cambridge212.34 Scientific212.82 Labs213.47 location.213.87 We215.71 are,216.26 so217.74 like217.98 I218.22 mentioned,218.3 we're218.62 a218.78 cancer218.94 diagnostic219.26 company.219.82 We're220.14 actually,220.38 leveraging222.14 a222.62 very222.78 new223.02 modality223.26 to223.98 cancer224.14 diagnostics.224.54 So,225.26 essentially,226.22 we're226.7 using226.94 atomic227.26 force227.74 microscopy,228.22 which229.02 is229.26 this,229.59 relatively230.16 new,230.79 microscopy231.68 technique,232.4 to,234 not235.03 image235.35 cells235.75 optically,236.4 but236.96 actually237.19 feel237.68 the238 surface238.16 of238.56 the238.72 cell.238.88 And239.35 with240.24 that,240.47 we240.72 can240.88 differentiate241.44 characteristics,242.31 from244.43 cells244.67 and245.15 determine245.79 whether246.27 they246.59 have246.75 cancer247.63 like248.11 features,248.43 or249.71 not250.03 just250.43 simply250.83 based251.15 on251.39 their251.55 biophysical251.87 characteristics.252.67 And253.63 so,253.95 our255.23 first255.55 indication255.95 is,256.67 bladder257.47 cancer257.71 reoccurrence.258.27 So259.07 essentially259.39 what259.88 happens260.12 is261.31 individuals261.47 with262.03 bladder262.35 cancer,262.75 they263.71 have264.12 to,264.35 have265.47 the265.79 tumor265.95 resected.266.44 And267.24 then267.39 when267.56 that267.79 happens,267.95 they268.35 undergo,268.59 routine270.51 surveillance271.15 because271.79 the,272.19 the273.6 chance273.76 of274.16 reoccurrence274.32 for274.96 bladder275.12 cancer275.52 is275.92 actually276.24 quite276.72 high.277.04 And277.76 so,277.92 the278.72 process278.88 is279.28 very279.52 invasive.279.84 280.32 They280.32 have280.48 to280.64 go280.72 into280.88 the281.12 clinic,281.28 several283.04 months283.44 out283.84 of284 the284.16 year284.32 to284.64 have284.88 a,285.12 scope,286 inserted287.4 and287.96 looked288.12 at288.44 their288.6 bladder,288.83 in289.71 order289.96 to290.19 determine290.36 if290.83 there's291 a291.24 recurrence291.31 of291.8 a291.88 tumor.292.04 So292.51 we293.56 are293.8 developing294.04 a294.68 diagnostic294.92 platform295.63 where296.12 we296.36 can,296.44 essentially297.71 take298.19 a298.36 urine298.6 sample,299.07 concentrate300.27 the300.92 cells301.15 down,301.48 fix302.85 them,303.17 put303.49 them303.65 on303.89 the303.97 slide,304.05 and304.45 feel304.69 the305.01 surface305.25 of306.05 the306.21 cells,306.37 and307.09 then307.25 we307.49 can307.57 differentiate,307.89 for309.33 clinicians309.73 and310.37 tell310.53 them310.77 there311.49 is311.73 a312.05 likelihood312.29 of312.85 cancer313.01 reoccurrence313.41 or314.29 not.314.53 So,315.01 we316.75 have317.07 established317.56 this318.04 workflow,318.28 where319.31 we319.8 have320.04 multiple320.36 IRB321.07 approved321.56 protocols321.96 from323.07 local323.31 hospitals323.72 in324.44 the324.68 Boston324.84 area325.31 where326.19 we,326.44 source327.07 urine327.48 samples,327.88 have328.7 them328.86 brought329.1 to329.34 our329.58 laboratory,329.82 and330.38 we330.46 process330.7 them331.18 for331.5 imaging.331.9 We333.34 have333.5 the333.82 samples333.98 prescreened334.54 at335.5 the335.58 hospital,335.82 so,336.38 no337.98 UTIs338.3 that339.02 are339.42 accepted339.66 in340.14 our340.3 samples.340.54 We341.66 also341.98 make342.54 sure342.78 that,343.1 if343.81 there's343.9 blood344.06 in344.46 the344.54 sample,344.78 it's345.1 also345.34 rejected345.65 at346.13 the346.22 hospital.346.38 So348.3 we348.54 accept348.86 clean349.42 urine349.74 samples350.06 that350.62 come350.78 into351.01 the351.25 lab.351.42 Then352.62 our352.86 testing353.1 personnel353.5 process354.22 those354.54 samples.354.86 We355.34 utilize355.5 a355.98 biosafety356.06 cabinet,356.78 standard358.71 PPE359.27 lab360.07 coats,360.39 gloves,362.23 safety362.47 glasses,362.95 all363.99 personnel364.31 have364.79 to365.03 be365.11 trained,365.27 with366.39 blood366.63 borne366.87 pathogen,367.27 protocols.369.27 370.31 So,370.31 we372.64 go372.73 through372.96 this373.13 processing373.37 step.373.93 We374.4 do374.64 have374.81 some374.96 liquid375.2 waste375.69 that376.08 is376.25 generated.376.49 We377.13 disinfect377.44 the378 liquid378.17 waste378.56 with378.88 hydrogen379.2 peroxide379.69 or380.25 d125.380.88 These382.4 are382.64 choices382.81 that383.2 we383.44 made383.61 because,383.85 we384.4 don't384.56 wanna384.73 mix385.28 urine385.44 and,385.68 bleach386.64 together387.04 just387.44 to387.6 try387.76 to388 minimize388.08 any388.48 kind388.72 of388.96 off389.04 gases389.28 that389.76 may389.92 occur,390.08 that391.2 would391.44 affect391.84 our392.24 personnel.392.56 So393.92 we394.16 have,394.32 a395.28 15395.36 minute395.84 or396.24 more396.48 contact396.88 time,397.36 with398.24 the398.56 biohazard398.88 waste,399.52 that400.99 is401.22 then,401.46 picked402.66 up402.9 by403.14 Veolia,403.54 this404.35 our,404.58 waste405.54 management405.87 carrier.406.5 Also407.7 the,408.1 contaminated408.99 solid409.7 waste410.02 goes410.43 into410.66 our411.06 waste411.22 processing411.63 stream,412.26 for,412.99 disposal413.78 through414.35 Veolia414.66 as415.22 well.415.38 We416.94 also417.18 do417.5 some417.9 cell418.62 culture,418.94 for420.14 our420.38 control420.7 samples.421.26 So421.9 we423.02 have423.26 a423.74 cell423.98 line424.22 that424.54 is,424.78 bladder425.42 cancer425.82 and426.38 then426.54 also426.78 a427.02 cell427.18 line427.5 that427.82 is,428.06 primary428.86 human429.87 cells.430.19 We've430.9 commercially431.31 purchased431.87 these432.26 through432.5 ATCC,432.82 so433.63 they've433.87 been434.1 screened.434.35 We435.54 do435.7 not435.87 do436.1 any436.35 recombinant436.58 DNA437.22 or437.54 nucleic437.78 acid438.26 work438.58 in438.82 general,438.99 and,440.66 we441.38 do441.63 not441.7 culture441.94 any442.34 pathogens,442.58 within444.02 the444.34 lab.444.5 And444.75 like444.9 I445.06 mentioned,445.22 we445.92 screen446.16 for446.48 UTIs446.72 in447.28 these447.36 samples.447.6 So449.92 I450.08 think450.16 I'll450.4 stop450.64 there450.88 and,451.28 ask452.08 there452.48 are453.04 any453.12 questions.453.36 PARSONS454.72 -454.72 Sure.454.72 And455.12 thank455.28 you455.52 so455.68 much455.84 for456.08 being456.24 here.456.48 So456.88 this457.12 is457.28 obviously457.52 well,458.4 not458.64 obviously.458.8 This459.71 is,459.79 a460.75 first460.9 in461.15 Watertown.461.31 So461.87 you,462.11 like,462.43 right463.23 on463.38 the463.55 line,463.71 do464.11 you464.35 need464.5 to464.9 get465.15 the465.31 permit?465.46 Do465.87 you466.02 need466.11 a466.35 registration?466.43 It's468.19 human468.43 samples,468.9 but469.46 you're469.71 rejecting470.58 blood471.31 contaminated.472.4 So473.04 but473.28 thank473.44 you.473.6 We473.84 do474.16 appreciate474.4 you475.04 spending475.28 time,475.76 coming476.4 here,476.8 because477.84 there478.16 was478.4 a478.48 bit478.56 of478.8 an478.96 internal,479.12 like,479.6 so481.28 let's481.52 just481.76 play481.92 it482.16 safe.482.24 But,482.64 also,482.8 I483.04 am483.2 glad483.28 you're483.52 here483.76 because483.92 this484.24 is484.4 definitely484.64 a485.04 first,485.12 the486.26 atomic486.35 force,486.82 microscopy.487.94 488.9 BILLINGS488.9 -488.9 Yep.488.9 490.19 PARSONS490.19 -490.19 So490.19 people490.5 tend490.82 to491.06 freak491.14 out491.38 when491.63 they491.87 hear492.1 the492.22 word492.35 atomic,492.75 in493.87 anything494.1 in494.82 a494.99 lab.495.14 So495.54 I495.79 do495.87 have496.02 a496.19 couple496.26 of496.58 questions.496.66 I'm497.14 not497.31 freaking497.54 out.497.94 But,498.1 is498.75 it498.99 your499.07 microscope499.39 or499.79 is500.03 Cambridge500.19 Scientific500.51 like,500.75 how500.99 much501.07 does501.31 Cambridge501.47 Scientific501.95 provide502.43 for502.67 you?502.83 504.19 BILLINGS504.19 -504.19 So504.19 they're504.35 not,504.59 providing505.39 any506.03 of506.19 our506.35 major506.51 equipment.506.91 I507.39 think507.55 they507.71 would507.87 have508.03 had508.27 a508.35 freezer508.83 and509.31 some,509.47 a510.19 centrifuge.510.35 Right.510.91 It's511.39 our511.71 microscopes.511.95 513.34 PARSONS513.34 -513.34 Okay.513.34 Do513.98 you514.13 know514.3 do514.62 you514.74 have514.86 it515.1 yet?515.25 516.13 BILLINGS516.13 -516.13 Yes.516.13 We516.38 do.516.62 517.25 PARSONS517.25 -517.25 Okay.517.25 Do517.58 is517.74 it517.89 a518.05 class518.22 two518.46 or518.62 a518.86 class518.93 three519.17 hour519.5 laser519.65 in519.98 it?520.13 Do520.3 you520.46 know?520.54 BILLINGS523.1 -523.1 I523.1 would525.17 assume525.42 it's525.82 class526.05 two,526.38 but526.62 I'm526.86 going527.01 to,527.25 hand528.43 that528.51 over528.83 to529.15 Amir.529.39 AMIR530.59 MONEMIAN530.59 -530.59 CELLENS530.59 INC.530.59 -530.59 Okay.530.59 Yeah.531.63 So532.91 eventually533.31 so533.95 AFM534.19 has534.67 been534.91 used535.07 in535.39 material535.79 science536.43 initially.537.15 Right.537.71 And538.19 recently538.43 in538.99 the539.15 last,539.31 like,539.71 few540.11 years,540.43 that540.91 comes541.07 into541.39 biology.541.71 And,543.38 for544.01 our544.25 purposes,544.5 we545.13 are545.29 using,545.54 like,546.1 the546.58 instrument546.82 itself,547.38 it's548.25 not548.5 like548.82 class549.05 four,549.29 class549.54 three549.86 instrument.550.1 It's550.5 not550.65 biohazard550.89 or551.62 things553.29 like553.54 that.553.77 And554.74 the555.05 sample555.22 that555.62 we555.86 are556.01 using556.17 are556.74 fixed557.05 and557.46 dried557.62 on558.27 a558.43 glass558.59 slide.559.31 So559.47 this559.71 Right.560.11 Sample560.27 that560.59 we560.83 are561.07 using561.23 is561.55 not561.63 also561.87 biohazardous.562.43 564.11 PARSONS564.11 -564.11 Right.564.11 I564.59 was564.75 just564.91 more565.15 concerned565.31 or565.71 just565.87 wanted566.03 to566.35 make566.43 sure566.59 that566.75 the,566.91 beam568.51 is568.83 fully568.99 enclosed,569.23 especially570.59 if570.99 it's571.15 a571.31 3571.47 r.571.71 572.61 BILLINGS572.61 -572.61 Yeah.572.61 It's572.85 not572.92 a573.25 beam.573.4 It's574.04 sorry.574.68 Go575.16 ahead,575.33 Amir.575.57 575.97 PARSONS575.97 -575.97 Yeah.575.97 And576.09 if576.21 and576.37 any576.52 maintenance576.92 that's577.25 gonna577.49 be577.73 on577.8 is578.04 done578.21 by578.45 a578.61 professional.578.76 580.04 MONEMIAN-580.04 Absolutely.580.04 Yeah.581.33 Okay.582.04 The582.76 late582.92 they583.25 designed583.57 it583.97 in584.13 a584.21 way584.29 that584.45 the584.76 laser584.92 is585.88 not586.36 coming586.6 out586.92 of587.16 the587.32 instrument587.56 at588.28 all.588.44 PARSONS588.84 -588.84 Gotcha.588.84 Yes.589.4 Okay.589.56 Alright.590.52 Excellent.590.92 Thank591.96 you.592.2 And593.16 then593.4 the593.88 hydrogen594.12 peroxide594.6 as595.24 a595.4 disinfectant.595.64 What's597.8 the598.12 concentration598.36 of599.16 hydrogen599.48 peroxide599.88 that600.36 you're600.44 using?600.68 601.38 BILLINGS601.38 -601.38 3%.601.38 602.42 PARSONS602.42 -602.42 3.602.42 Okay.602.82 It's603.3 3,603.46 not605.22 3-0.605.93 607.06 BILLINGS607.06 -607.06 Yeah.607.06 Not607.3 30.607.46 No.607.77 3.608.18 Yes.610.25 610.65 PARSONS610.65 -610.65 Alright.610.65 Perfect.611.46 Thank611.93 you.612.18 Those612.5 are612.74 my612.89 only613.06 questions.613.38 Tim,614.58 I'm614.98 just615.13 gonna615.3 go,615.62 counterclockwise.616.48 Tim,617.68 do617.84 you617.92 have618 any618.08 questions618.24 for618.56 Nicole618.72 or619.12 Amir?619.2 619.92 TIMOTHY619.92 MAGUIRE619.92 -619.92 BIOSAFETY619.92 COMMITTEE619.92 MEMBER619.92 -619.92 First619.92 of620.32 all,620.48 really620.96 cool621.2 idea.621.44 My621.76 wife622 worked622.24 on622.48 it.622.64 I622.8 found622.88 on623.2 proteins623.28 about623.84 20624 years624.32 ago,624.48 so624.64 it's624.8 625.04 BILLINGS625.04 -625.04 Oh,625.04 very625.12 nice.625.36 625.6 MAGUIRE625.6 -625.6 Keep625.6 them625.76 on625.92 cells.626.08 And,626.4 now626.8 no627.04 other627.2 questions627.44 for627.84 me.628.08 628.24 MONEMIANE628.24 -628.24 Thank628.24 you.628.4 629.44 PARSONS-629.44 Thank629.44 you.629.76 Deb,631.65 any631.98 questions?632.13 634.29 DEB634.29 MCEWAN634.29 -634.29 BIOSAFETY634.29 COMMITTEE634.29 MEMBER634.29 -634.29 Love634.29 to634.53 ask634.69 science634.93 questions,635.33 but635.74 for635.98 safety636.21 questions636.62 641.41 MAGUIRE641.41 -641.41 We'll641.41 do641.65 a641.81 lunch641.89 and642.21 learn642.38 later.642.69 Yeah.643.98 SHOW NON-ESSENTIAL DIALOGUE
644.32 SPEAKER1644.32 -644.32 No.644.32 That's644.4 do645.12 that.645.2 645.6 SPEAKER7645.6 -645.6 Yes.645.6 Yes.645.92 Absolutely.646.4 Yes.647.44 648 SPEAKER6648 -648 Yeah.648 650.24 PARSONS650.24 -650.24 No.650.24 It650.56 is650.64 exciting.650.88 It651.28 is651.36 different,651.6 or652.48 new.652.72 Novel.653.12 It's653.44 novel.653.68 So,654.56 Ralph,656.4 any656.72 questions657.04 for657.44 Nicole657.6 or658 Amir?658.08 658.64 RALPH658.64 MELE658.64 -658.64 BIOSAFETY658.64 COMMITTEE658.64 MEMBER658.64 -658.64 No658.64 questions.658.88 660.16 PARSONS660.16 -660.16 Okay.660.16 Great.660.4 Thank660.73 you.660.88 Okay.662.16 Maureen,662.96 is663.76 the664.16 board664.4 of664.73 health664.8 meeting664.96 in665.45 August?665.68 674.13 FOLEY674.13 -674.13 Maureen's674.13 having674.61 some675.57 issues,676.37 but,676.69 yes,676.93 the677.17 board677.33 of677.57 health677.81 meeting678.13 should679.09 be679.33 next679.57 Wednesday679.89 at681.09 7681.41 or681.73 07:30.681.89 We682.61 will682.77 confirm683.09 on683.73 Monday.683.89 PARSONS685.16 -685.16 Excellent.685.16 Thank685.49 you,685.8 Abbey.685.88 I686.21 really686.37 appreciate686.52 it.686.85 Okay.687.49 So,687.8 Nicole689.57 and690.04 Amir,690.85 so691.57 we691.8 do691.97 not,692.13 issue694.29 permits.694.61 We695.64 recommend695.8 to696.29 the696.37 board696.52 of696.76 health696.85 or697.34 not697.74 recommend.697.98 So699.1 you699.42 will,699.66 so700.3 next700.46 Wednesday,700.7 as701.1 Abbey701.34 said,701.58 is701.82 when701.98 they702.54 meet.702.7 So702.94 exactly703.34 what703.74 you703.9 did,704.06 this704.54 evening.704.78 But705.42 first,705.66 and707.5 then707.66 I707.82 can't707.9 do708.14 this,708.38 my708.86 fellow709.1 members.709.42 We710.06 need710.3 to710.46 have710.54 a710.7 motion,710.78 to712.67 accept712.9 the713.47 permit713.63 as714.11 submitted.714.26 716.9 FOLEY716.9 -716.9 This716.9 I717.47 can717.63 speak718.42 now.718.67 719.63 PARSONS719.63 -719.63 Thank719.63 you.719.87 MELE722.42 -722.42 I'll722.42 make722.59 a722.83 motion.722.9 Accept723.95 the724.42 permit724.59 as724.9 submitted.725.07 727.44 MCEWAN727.44 -727.44 Second.727.44 729.52 PARSONS729.52 -729.52 Great.729.52 So,730.16 Maureen,731.68 can732 we732.16 take732.32 a732.48 quick732.56 vote?732.8 736 FOLEY736 -736 Brad,736 do736.32 you736.48 want736.56 me736.72 to736.88 do737.04 a737.12 vote737.2 count?737.44 738.32 PARSONS738.32 -738.32 Yes,738.32 please.738.56 If738.88 we738.96 could739.12 do739.2 a739.36 quick739.44 vote.739.76 Yes.740.08 SHOW NON-ESSENTIAL DIALOGUE
742.49 SPEAKER2742.49 -742.49 Deb742.49 McEwen?742.88 743.68 SPEAKER6743.68 -743.68 Yes.743.68 745.28 SPEAKER2745.28 -745.28 Ralph745.28 Meeley?745.68 746.57 SPEAKER3746.57 -746.57 Yes.746.57 747.52 SPEAKER2747.52 -747.52 Jim747.52 McGuire?747.85 748.57 SPEAKER4748.57 -748.57 Yes.748.57 749.37 SPEAKER2749.37 -749.37 And749.37 Brad749.92 Parsons.750.25 751.37 PARSONS751.37 -751.37 Yes.751.37 Alright.752 So,752.49 thank753.76 you754 for754.16 being754.33 here.754.57 You754.88 do755.04 not755.28 have755.45 to755.68 stay.755.76 We756.63 are756.79 not756.87 offended757.11 when757.51 people757.67 who757.91 have758.07 finished758.23 the758.55 presentation758.63 leave.759.51 We760.15 get760.31 it.760.39 But,761.35 yes,761.59 as762.07 Abbey762.47 said,762.71 you'll762.95 get763.19 more763.43 information763.59 by764.47 next764.71 Monday,764.95 to766.71 confirm766.95 the767.75 time.767.91 It's768.31 also768.55 by768.87 Zoom,769.03 for770.58 the770.82 board770.98 of771.29 health771.38 meeting.771.54 And771.86 best772.1 of772.34 luck772.41 with772.65 your772.82 research.772.98 773.62 BILLINGS773.62 -773.62 Great.773.62 Thank773.93 you774.17 so774.34 much.774.5 We774.82 appreciate774.98 it.775.38 MONEMIANE775.86 -775.86 Thank775.86 you776.1 very776.25 much.776.58 SHOW NON-ESSENTIAL DIALOGUE
776.98 SPEAKER4776.98 -776.98 Thank776.98 you777.13 so777.22 much.777.38 777.62 SPEAKER1777.62 -777.62 You're777.62 welcome.777.77 Thank778.1 you.778.34 779.22 SPEAKER2779.22 -779.22 Bye779.22 bye.779.38 779.77 SPEAKER1779.77 -779.77 Alrighty.779.77 Question.781.22 782.64 FOLEY782.64 -782.64 What782.64 did783.92 she784.24 say?784.4 She784.8 said784.96 atomic785.44 force?786.48 788.32 PARSONS788.32 -788.32 It's788.32 called788.8 AFM,789.2 atomic789.92 force790.48 microscopy.791.04 It's794.63 not794.88 as795.19 scary795.36 as795.67 it795.83 sounds796 because796.15 when796.48 I796.55 first796.71 read796.95 that,797.19 I797.6 was797.75 like,798 oh,798.71 woah.800.63 I802 mean,802.15 I've802.32 never802.48 seen802.79 has803.12 anyone803.27 here803.6 seen804 in804.63 you805.6 okay.805.83 Tim,806.48 you've806.71 seen806.95 one?807.79 MAGUIRE807.79 -807.79 Yeah.807.79 My807.95 wife808.11 did808.35 it808.59 back808.75 in808.99 Rutgers809.23 back,809.55 like,809.87 20810.03 years810.35 ago.810.59 Yeah.810.99 811.71 PARSONS811.71 -811.71 Oh,811.71 so811.87 it812.03 has812.11 been812.43 around812.51 for812.75 oh,812.99 813.55 MAGUIRE813.55 -813.55 I813.55 have813.55 pros813.79 on814.27 it.814.35 There814.43 isn't814.67 pros814.99 for815.23 cells815.39 now,815.63 and815.79 they815.95 look816.11 at816.27 the816.43 mechanical816.59 forces817.15 on817.63 it.817.79 And817.87 based818.03 on818.27 the818.43 mechanical818.59 forces,819.15 they819.55 can819.71 relate819.87 that820.27 to820.59 kind820.83 of820.99 a821.23 a821.47 metastatic821.55 score.822.43 So822.75 it's822.91 neat823.15 that823.39 you823.55 could823.72 do823.79 it823.96 on824.12 the824.27 full824.36 cell824.75 surface825.08 level825.55 now825.88 and826.12 not826.27 just826.51 single826.75 proteins.827.15 Yeah.827.63 It's827.79 pretty827.96 cool.828.12 PARSONS828.43 -828.43 Oh,828.43 that's828.51 that829.08 is829.32 cool.829.55 So830.91 I831.15 had831.24 never831.39 heard831.63 of831.79 this831.88 microscope.832.12 And832.75 I835.91 did836.07 a836.23 little836.31 research.836.55 837.03 MAGUIRE837.03 -837.03 Grass837.03 too.837.51 The837.83 grass837.99 out838.31 in838.55 the838.71 pretty838.79 839.27 PARSONS839.27 -839.27 Yes.839.27 Yeah.839.75 So840.15 even840.39 a840.63 quick840.79 Google,841.03 like,841.35 I841.51 didn't841.59 even841.75 ask841.99 anyone842.23 in842.63 the842.71 lab.842.87 It844.07 looks844.23 it's844.79 really845.27 compelling845.59 stuff.846.23 And847.67 just,851.09 but851.09 there851.33 is851.49 a851.57 potential851.8 safety852.29 thing852.68 if852.93 someone853.09 mucks853.4 around,853.64 with854.52 that854.85 with855.17 the855.4 laser.855.57 Okay.857.97 So861.4 we861.64 have861.73 an861.88 amendment862.05 for862.61 for863.1 FTGEN,863.58 moving865.82 to866.14 Dexter866.46 Avenue.867.1 870.3 HONGDUAN870.3 -870.3 FT870.3 JAN870.3 -870.3 Hello,870.3 everyone.870.78 This872.06 is,872.78 Hongduan.873.34 Can873.98 you874.22 hear874.38 me?874.54 875.34 PARSONS875.34 -875.34 We875.34 can.875.58 876.44 HONGDUAN876.44 -876.44 Okay.876.44 Great.876.76 So,878.28 again,878.76 thank879.73 you879.96 all880.37 very880.68 much880.92 for881.25 the881.4 opportunity881.64 to,882.44 review883.32 our883.8 amendment.884.13 So885.8 my886.13 name886.28 is886.44 Hongduan,886.76 and,887.57 I'm888.2 the888.44 IBC888.68 chair889.25 of,889.64 FT890.52 JAN.892.11 Just892.11 a892.35 overview892.43 of892.99 our893.15 company.893.47 Our894.35 company894.59 is894.99 an895.39 AV895.63 gene896.03 therapy896.27 company,896.75 and897.63 our897.95 goal898.27 is898.67 to898.91 develop899.15 a899.55 safe,899.71 effective,900.19 and,900.99 affordable901.63 gene902.51 therapies902.83 for903.79 some904.03 serious904.27 diseases904.83 with905.79 unmet906.03 medical906.59 needs.907.32 So909.24 our909.88 amendment910.27 today910.84 is911.32 just911.8 for912.2 our912.51 company,912.84 location913.88 change.914.44 So915.72 for916.51 our916.84 all917.32 the917.56 protocols917.8 will918.44 stay918.84 the919.08 same.919.24 So919.76 currently,920 we920.64 have920.72 3920.96 IVC921.52 protocols922.4 covering923.68 AV924.48 production,924.8 AV926 analytical926.32 analysis,927.04 and927.92 the928.16 AV928.4 potency928.64 ISAs.929.2 So932.17 currently,932.82 we933.53 are933.62 at933.86 155934.25 Arlington935.62 Street,936.17 and,937.05 we937.53 all937.77 know937.93 it's938.17 one938.41 of938.65 Cambridge939.05 Scientific939.77 Labs940.34 facility.940.82 And942.1 we942.34 are942.58 planning942.74 to943.22 relocate943.62 to944.5 200944.89 Dexter945.7 Avenue.946.17 That's947.56 another947.64 facility,948.28 in949.72 Watertown.950.04 As952.44 I952.6 said,952.76 the,953.32 amendment954.36 is954.92 only955.24 for955.56 location956.04 change,956.6 and957.48 the957.8 nature957.96 of958.36 our958.52 work,958.76 including959.5 our960.13 procedure960.46 material961.33 we961.98 use,962.21 our962.93 safety963.17 level,963.74 and964.29 the964.7 waste964.93 handling965.25 procedures966.21 will967.01 all967.41 stay967.65 the967.98 same968.13 as969.1 we969.33 are969.5 in969.82 the969.89 current970.05 location.970.38 So972.36 we972.6 have972.76 updated973.08 all973.72 our974.04 protocols974.28 with975.08 the975.32 address975.96 change976.36 and977.24 the977.56 conducted,977.64 interim978.52 IBC979.24 meeting979.8 on980.92 July981.16 23,981.73 and,982.76 committee983.72 reviewed985.55 and985.96 approved986.36 our987.32 revised987.96 protocols.988.51 That's991.32 all991.55 for991.79 me.992.03 Any992.51 questions?993 995.08 PARSONS995.08 -995.08 Great.995.08 Thank995.48 you.995.71 No.996.03 We996.2 appreciate996.36 you996.75 being996.91 here.997.15 And,997.39 yes,998.87 while999.03 your999.27 science999.43 may999.75 not999.91 be1000.07 changing,1000.23 we1000.55 do1000.79 ask1001.03 that1001.27 people1001.43 come1001.67 in1001.83 when1001.99 it's1002.15 a1002.39 significant1002.55 what1002.95 we1003.11 consider1003.19 a1003.59 significant1003.67 move.1004.23 SHOW NON-ESSENTIAL DIALOGUE
1004.79 SPEAKER91004.79 -1004.79 Mhmm.1004.79 1005.91 PARSONS1005.91 -1005.91 And1005.91 this1006.15 is1006.39 so1006.63 congratulations.1006.87 I1007.59 mean,1007.67 this1007.99 is1008.15 so1008.47 if1008.79 I1008.91 if1009.11 I'm1009.35 reading1009.59 the1010.55 floor1010.79 plan1011.11 right,1011.43 you're1012.23 getting1012.47 a1012.71 lot1012.79 of1013.03 lab1013.19 space.1013.43 Is1013.83 that1013.91 correct?1014.07 1014.83 HONGDUAN1014.83 -1014.83 That's1014.83 correct.1015.07 So1015.47 that's1015.63 one1015.87 of1016.02 the1016.18 reason1016.26 we1016.67 are1016.9 making1016.99 the1017.23 1017.55 PARSONS1019.55 -1019.55 So1019.55 the1020.5 numbers1020.67 so1022.9 you1023.3 get1023.38 1023.87 HONGDUAN1023.87 -1023.87 2,000.1023.87 1025.46 PARSONS1025.46 -1025.46 Yeah.1025.46 Okay.1025.95 Alright.1026.59 So1027.63 but1029.48 just1029.56 for1029.8 our1030.04 own,1030.2 you1030.52 know,1030.68 peace1030.92 of1031.16 mind.1031.24 So1031.56 while1031.72 you1031.96 are1032.28 increasing1032.6 dramatically1033.24 the1033.96 amount1034.28 of1034.44 square1034.6 footage1034.84 of1035.16 your1035.32 lab,1035.56 you're1036.04 still1036.36 staying1036.68 within,1037 like,1037.48 a1037.64 small1037.8 quantity.1038.12 Like,1040.36 nothing1040.68 you're1041.16 not1041.4 covering1041.8 anything1042.2 over1042.52 101042.68 liters1042.92 or1043.24 anything?1043.4 Okay.1043.8 1044.27 HONGDUAN1044.27 -1044.27 No.1044.27 1047.07 PARSONS1047.07 -1047.07 Alright.1047.07 Do1047.63 you1047.94 think1048.11 so1048.66 do1050.83 you1050.98 anticipate1051.22 maybe1052.03 generating1052.35 more1052.74 hazardous1053.07 waste1053.54 but1053.94 than1054.11 before?1054.35 Because1054.66 I1055.07 believe1055.14 last1055.7 time1056.03 HONGDUAN1056.59 -1056.59 No.1056.59 The1056.9 scope1057.22 of1057.54 the1057.7 SDG1057.79 will1059.36 stay1059.6 the1060 same.1060.16 1061.2 PARSONS1061.2 -1061.2 Okay.1061.2 So1061.6 expect1062.24 the1062.64 hazardous1062.88 waste.1063.28 Okay.1063.52 And1067.36 I1067.52 also1067.6 got1067.84 really1068 confused1068.24 because1068.56 the1068.72 company1068.88 that1069.2 we1069.44 just1069.52 presented1069.76 is1070.32 moving1070.56 to1070.88 155.1071.28 1072.48 HONGDUAN1072.48 -1072.48 Correct.1072.48 With1073.85 the1074.01 lander.1074.16 1074.48 PARSONS1074.48 -1074.48 Right?1074.48 So,1075.92 when1076.64 I1077.13 first1077.2 started,1077.44 I1077.68 was,1077.77 like,1077.92 getting1078.09 a1078.33 little1078.4 getting1078.81 a1079.05 little1079.13 mixed1079.44 up.1079.68 Okay.1079.85 Alright.1080.33 So1080.57 those1080.81 are1080.88 all1081.13 my1081.29 questions.1081.44 I'm1081.77 gonna1081.85 go1082.01 the1082.16 other1082.24 way1082.4 around.1082.57 Ralph,1083.05 any1083.37 questions?1083.61 1085.57 MELE1085.57 -1085.57 Yeah.1085.57 So1085.89 I1086.29 see1086.53 the1086.85 two1087.01 spaces1087.41 that1087.89 you1088.05 have.1088.21 Is1088.77 there1088.93 an1089.25 interconnection1089.41 between1089.89 them,1090.13 or1090.37 do1090.45 you1090.61 have1090.69 to1090.93 go1091.01 all1091.33 the1091.57 way1091.65 around1091.89 the1092.29 building1092.53 to1092.85 get1093.01 from1093.49 Suite1094.21 1401094.61 to1095.33 120?1095.65 1096.77 HONGDUAN1096.77 -1096.77 They1096.77 are1097.01 connected.1097.17 1097.97 MELE1097.97 -1097.97 They1097.97 are1098.21 connected?1098.37 1099.12 HONGDUAN1099.12 -1099.12 Yes.1099.12 But1099.91 they1100.08 are1100.23 doors1100.56 we1101.04 can1101.28 close1101.76 and1102.32 open.1102.56 1103.67 MELE1103.67 -1103.67 Okay.1103.67 I1103.67 don't1103.84 I1103.99 just1104.15 don't1104.32 see1104.47 a1104.63 door1104.8 on1105.12 the1105.2 floor1105.36 plan1105.6 that1105.84 shows1106.08 the1106.39 interconnection1106.56 between1107.12 the1107.36 two.1109.36 HONGDUAN1109.36 -1109.36 I1109.36 can1109.6 double1109.84 check,1110.15 but,1110.39 definitely,1110.8 we1111.36 don't1111.52 need1111.76 to1111.91 go1112.08 around1112.32 the1112.63 building1112.8 to.1113.67 Go1114.15 to1114.23 the1114.73 other.1114.81 1115.85 MELE1115.85 -1115.85 So1115.85 there1116.09 is1116.25 a1116.33 connection1116.41 between,1116.89 Suite1118.49 1201118.89 and1119.37 140.1119.53 Okay.1120.01 That1122.09 was1122.33 the1122.49 only1122.65 question1122.89 I1123.21 had.1123.29 If1123.45 you1123.61 could,1123.77 update1125.13 that1125.53 so1125.93 we1126.09 could1126.17 see1126.41 it1126.57 a1126.73 little1126.81 clearer,1127.05 that'd1127.37 be1127.53 great.1127.77 1128.41 HONGDUAN1128.41 -1128.41 Okay.1128.41 Yes.1129.13 1133.95 PARSONS1133.95 -1133.95 So1133.95 Ralph1134.36 updated1135.71 41137.95 point.1138.28 Great.1140.76 Thank1140.99 you,1141.15 Ralph.1141.32 Deb,1142.04 any1142.36 questions?1142.6 1144.87 MCEWAN1144.87 -1144.87 No.1144.87 But1145.51 I1145.75 just1145.83 wanna1146.07 say,1146.31 like,1146.55 I1146.87 appreciate1147.03 how1147.51 clear1147.83 the1149.19 documents1149.83 were1150.31 in1150.55 the1150.63 presentation1150.71 that,1151.19 like,1151.35 you1151.59 know,1151.67 the1151.91 scope1152.07 isn't1152.39 changing.1152.71 It's1153.11 just1153.27 the1153.59 location.1153.67 So1154.23 thank1155.03 you.1155.27 1155.67 HONGDUAN1155.67 -1155.67 Okay.1155.67 Thank1156.31 you.1156.55 1160.23 PARSONS1160.23 -1160.23 Tim,1160.23 any1160.55 questions?1160.79 1161.75 MAGUIRE1161.75 -1161.75 Oh,1161.75 no.1161.9 None1162.23 for1162.47 me.1162.55 Thank1162.79 you.1162.87 1163.99 PARSONS1163.99 -1163.99 Okay.1163.99 Great.1164.31 Alright.1164.95 So1165.35 good1165.66 news.1165.9 You1166.63 do1166.87 not1167.03 have1167.18 to1167.31 go1167.42 to1167.66 the1167.75 board1167.9 of1168.14 health1168.31 for1168.55 this.1168.71 1169.42 HONGDUAN1169.42 -1169.42 Oh,1169.42 great.1169.59 1169.9 PARSONS1169.9 -1169.9 Especially1169.9 yeah.1170.63 Since1171.03 the1171.35 science1171.51 hasn't1171.83 changed,1172.23 or1173.83 isn't1173.99 changing1174.31 yet,1174.79 and1176.39 the1176.55 volume1176.79 is1177.19 staying1177.35 the1177.67 same,1177.91 you1179.43 know,1179.59 these1179.91 are1180.15 the1180.23 things1180.31 the1180.79 this1181.27 committee1181.51 does1181.99 have,1182.23 some1184.15 authority,1185.11 over.1186.63 So1187.91 yeah.1188.4 But1188.9 as1189.22 Ralph1189.3 said,1189.7 if1190.02 you1190.11 could1190.35 please,1190.51 come1191.38 up1191.63 with1191.78 the1191.87 floor1192.02 plan1192.35 that1192.59 shows1192.83 because1193.38 I1193.63 see1193.7 what1193.87 he1194.02 sees1194.18 now.1194.42 I1194.66 had1194.98 to1195.22 zoom1195.38 out,1195.63 a1196.42 bit,1196.59 but1196.83 it1196.98 does1197.14 look1197.38 like1197.54 the1198.02 only1198.18 thing1198.42 that1198.59 connects1198.74 1401199.14 and1199.7 1201200.11 is1200.42 a1200.59 room,1200.74 like1202.38 a1202.46 storage1202.7 room,1203.1 but1203.34 the1203.58 door1203.66 opens1203.98 in1204.3 01:40.1204.46 So,1205.58 yeah,1206.94 if1207.18 you1207.34 could1207.5 just1207.58 send1208.14 us1208.38 that,1208.54 as1209.42 soon1209.58 as1209.82 you1209.9 can,1210.14 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the1297.18 authenticator1297.63 wants1298.27 to1298.51 go1298.59 to1298.74 a1298.9 specific1299.07 device1299.46 even1300.74 though1300.9 it's1301.07 the1301.22 same1301.3 account.1301.55 1302.51 PARSONS1302.51 -1302.51 Right.1302.51 Yeah.1303.14 Okay.1303.55 Yeah.1303.87 Because1304.18 it1304.35 won't1304.51 even1304.66 recognize1304.9 my1305.3 email.1305.46 Yes,1305.79 Aby1305.94 1306.35 ABBEY1306.35 MYERS1306.35 -1306.35 CITY1306.35 OF1306.35 WATERTOWN1306.35 -1306.35 Yeah.1306.35 I1306.59 would1306.66 just1306.83 tell1307.07 him,1307.22 like1307.46 Ralph1307.79 said,1308.03 just1308.27 tell1308.42 him1308.59 that1308.83 you1308.98 got1309.14 a1309.3 new1309.46 phone.1309.63 That1310.9 might1311.22 1312.42 PARSONS1312.42 -1312.42 Yeah.1312.42 I1312.58 just1312.66 made1312.9 the1313.14 note1313.3 to1313.54 do1313.62 that.1313.78 Yeah.1314.02 That1315.46 should1315.7 expedite1316.18 the1316.74 resolution.1318.18 I1320.74 know1320.9 I1321.06 shouldn't1321.14 have1321.46 gotten1321.54 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